NIOSH Pocket Guide to Chemical Hazards

Diisobutyl ketone CAS 108-83-8
[(CH3)2CHCH2]2CO RTECS MJ5775000
Synonyms & Trade Names
DIBK; sym-Diisopropyl acetone; 2,6-Dimethyl-4-heptanone; Isovalerone; Valerone
DOT ID & Guide
1157 127
Exposure
Limits
NIOSH REL: TWA 25 ppm (150 mg/m3)
OSHA PEL: TWA 50 ppm (290 mg/m3)
IDLH 500 ppm Conversion 1 ppm = 5.82 mg/m3
Physical Description
Colorless liquid with a mild, sweet odor.
MW: 142.3
BP: 334°F
FRZ: -43°F
Sol: 0.05%
VP: 2 mmHg
IP: 9.04 eV

Sp.Gr: 0.81
Fl.P: 120°F
UEL(200°F): 7.1%
LEL(200°F): 0.8%

Class II Combustible Liquid: Fl.P. at or above 100F and below 140F.
Incompatibilities & Reactivities
Strong oxidizers
Measurement Methods
NIOSH 1300; OSHA 7
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: No recommendation
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
Up to 500 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)/(APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, nose, throat; headache, dizziness; dermatitis; liver, kidney damage
Target Organs Eyes, skin, respiratory system, central nervous system, liver, kidneys
See also: INTRODUCTION