NIOSH Pocket Guide to Chemical Hazards

Hexafluoroacetone CAS 684-16-2
(CF3)2CO RTECS UC2450000
Synonyms & Trade Names
Hexafluoro-2-propanone; 1,1,1,3,3,3-Hexafluoro-2-propanone; HFA; Perfluoroacetone
DOT ID & Guide
2420 125
NIOSH REL: TWA 0.1 ppm (0.7 mg/m3) [skin]
OSHA PEL†: none
IDLH N.D. Conversion 1 ppm = 6.79 mg/m3
Physical Description
Colorless gas with a musty odor. [Note: Shipped as a liquefied compressed gas.]
MW: 166.0
BP: -18°F
FRZ: -188°F
Sol: Reacts
VP: 5.8 atm
IP: 11.81 eV
RGasD: 5.76

Fl.P: NA

Nonflammable Gas, but highly reactive with water & other substances, releasing heat.
Incompatibilities & Reactivities
Water, acids [Note: Hygroscopic (i.e., absorbs moisture from the air); reacts with moisture to form a highly acidic sesquihydrate.]
Measurement Methods
None available
Personal Protection & Sanitation
Skin: Prevent skin contact/Frostbite
Eyes: Prevent eye contact/Frostbite
Wash skin: No recommendation
Remove: No recommendation
Change: No recommendation
Provide: Frostbite
First Aid (See procedures)
Eye: Frostbite
Skin: Frostbite
Breathing: Respiratory support

Respirator Recommendations To be added later
Exposure Routes inhalation, skin absorption, skin and/or eye contact
Symptoms Irritation eyes, skin, mucous membrane, respiratory system; pulmonary edema; liquid: frostbite; in animals: teratogenic, reproductive effects; kidney injury
Target Organs Eyes, skin, respiratory system, kidneys, reproductive system