NIOSH Pocket Guide to Chemical Hazards

Hexone CAS 108-10-1
CH3COCH2CH(CH3)2 RTECS SA9275000
Synonyms & Trade Names
Isobutyl methyl ketone, Methyl isobutyl ketone, 4-Methyl 2-pentanone, MIBK
DOT ID & Guide
1245 127
Exposure
Limits
NIOSH REL: TWA 50 ppm (205 mg/m3) ST 75 ppm (300 mg/m3)
OSHA PEL: TWA 100 ppm (410 mg/m3)
IDLH 500 ppm Conversion 1 ppm = 4.10 mg/m3
Physical Description
Colorless liquid with a pleasant odor.
MW: 100.2
BP: 242°F
FRZ: -120°F
Sol: 2%
VP: 16 mmHg
IP: 9.30 eV

Sp.Gr: 0.80
Fl.P: 64°F
UEL(200°F): 8.0%
LEL(200°F): 1.2%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities
Strong oxidizers, potassium tert-butoxide
Measurement Methods
NIOSH 1300; OSHA 7
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water flush promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
Up to 500 ppm: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)*/(APF = 10) Any supplied-air respirator*/(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, mucous membrane; headache, narcosis, coma; dermatitis; in animals: liver, kidney damage
Target Organs Eyes, skin, respiratory system, central nervous system, liver, kidneys
See also: INTRODUCTION