NIOSH Pocket Guide to Chemical Hazards

Isopropyl ether CAS 108-20-3
(CH3)2CHOCH(CH3)2 RTECS TZ5425000
Synonyms & Trade Names
Diisopropyl ether, Diisopropyl oxide, 2-Isopropoxy propane
DOT ID & Guide
1159 127
Exposure
Limits
NIOSH REL: TWA 500 ppm (2100 mg/m3)
OSHA PEL: TWA 500 ppm (2100 mg/m3)
IDLH 1400 ppm [10%LEL] Conversion 1 ppm = 4.18 mg/m3
Physical Description
Colorless liquid with a sharp, sweet, ether-like odor.
MW: 102.2
BP: 154°F
FRZ: -76°F
Sol: 0.2%
VP: 119 mmHg
IP: 9.20 eV

Sp.Gr: 0.73
Fl.P: -18°F
UEL: 7.9%
LEL: 1.4%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities
Strong oxidizers, acids [Note: Unstable peroxides may form on long contact with air.]
Measurement Methods
NIOSH 1618; OSHA 7
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation

First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash promptly
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA
Up to 1400 ppm: (APF = 10) Any chemical cartridge respirator with organic vapor cartridge(s)*/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)*/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/(APF = 10) Any supplied-air respirator*/(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, ingestion, skin and/or eye contact
Symptoms Irritation eyes, skin, nose; respiratory discomfort; dermatitis; in animals: drowsiness, dizziness, unconsciousness, narcosis
Target Organs Eyes, skin, respiratory system, central nervous system
See also: INTRODUCTION