NIOSH Pocket Guide to Chemical Hazards

Kepone CAS 143-50-0
C10Cl10O RTECS PC8575000
Synonyms & Trade Names
Chlordecone; Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)-pentalen-2-one; Decachlorooctahydro-kepone-2-one; Decachlorotetrahydro-4,7-methanoindeneone
DOT ID & Guide
NIOSH REL: Ca TWA 0.001 mg/m3 See Appendix A
OSHA PEL: none
IDLH Ca [N.D.] Conversion
Physical Description
Tan to white, crystalline, odorless solid. [insecticide]
MW: 490.6
BP: Sublimes
MLT: 662°F (Sublimes)
Sol(212°F): 0.5%
VP(77°F): 3 x 10-7 mmHg
IP: ?

Sp.Gr: ?
Fl.P: NA

Noncombustible Solid
Incompatibilities & Reactivities
Acids, acid fumes
Measurement Methods
NIOSH 5508
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated/Daily
Remove: When wet or contaminated
Change: Daily
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister having a high-efficiency particulate filter/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Headache, anxiety, tremor; liver, kidney damage; visual disturbance; ataxia, chest pain, skin erythema (skin redness); testicular atrophy, low sperm count; [potential occupational carcinogen]
Target Organs Eyes, skin, respiratory system, central nervous system, liver, kidneys, reproductive system

Cancer Site [in animal: liver cancer]