NIOSH Pocket Guide to Chemical Hazards

Nicotine CAS 54-11-5
C5H4NC4H7NCH3 RTECS QS5250000
Synonyms & Trade Names
3-(1-Methyl-2-pyrrolidyl)pyridine
DOT ID & Guide
1654 151
Exposure
Limits
NIOSH REL: TWA 0.5 mg/m3 [skin]
OSHA PEL: TWA 0.5 mg/m3 [skin]
IDLH 5 mg/m3 Conversion
Physical Description
Pale-yellow to dark-brown liquid with a fish-like odor when warm. [insecticide]
MW: 162.2
BP: 482°F (Decomposes)
FRZ: -110°F
Sol: Miscible
VP: 0.08 mmHg
IP: 8.01 eV

Sp.Gr: 1.01
Fl.P: 203°F
UEL: 4.0%
LEL: 0.7%

Class IIIB Combustible Liquid: Fl.P. at or above 200F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids
Measurement Methods
NIOSH 2544, 2551
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA
Up to 5 mg/m3: (APF = 10) Any supplied-air respirator/(APF = 50) Any self-contained breathing apparatus with a full facepiece
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Nausea, salivation, abdominal pain, vomiting, diarrhea; headache, dizziness, hearing, visual disturbance; confusion, lassitude (weakness, exhaustion), incoordination; cardiac arrhythmias; convulsions, dyspnea (breathing difficulty); in animals: teratogenic effects
Target Organs central nervous system, cardiovascular system, lungs, gastrointestinal tract, reproductive system
See also: INTRODUCTION