NIOSH Pocket Guide to Chemical Hazards

Pyridine CAS 110-86-1
C5H5N RTECS UR8400000
Synonyms & Trade Names
Azabenzene, Azine
DOT ID & Guide
1282 129
Exposure
Limits
NIOSH REL: TWA 5 ppm (15 mg/m3)
OSHA PEL: TWA 5 ppm (15 mg/m3)
IDLH 1000 ppm Conversion 1 ppm = 3.24 mg/m3
Physical Description
Colorless to yellow liquid with a nauseating, fish-like odor.
MW: 79.1
BP: 240°F
FRZ: -44°F
Sol: Miscible
VP: 16 mmHg
IP: 9.27 eV

Sp.Gr: 0.98
Fl.P: 68°F
UEL: 12.4%
LEL: 1.8%

Class IB Flammable Liquid: Fl.P. below 73F and BP at or above 100F.
Incompatibilities & Reactivities
Strong oxidizers, strong acids
Measurement Methods
NIOSH 1613; OSHA 7
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet (flammable)
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Water flush immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA
Up to 125 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode/(APF = 25) Any powered, air-purifying respirator with organic vapor cartridge(s)
Up to 50 ppm: (APF = 50) Any chemical cartridge respirator with a full facepiece and organic vapor cartridge(s)/(APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/(APF = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and organic vapor cartridge(s)/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Up to 1000 ppm: (APF = 2000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes; headache, anxiety, dizziness, insomnia; nausea, anorexia; dermatitis; liver, kidney damage
Target Organs Eyes, skin, central nervous system, liver, kidneys, gastrointestinal tract,
See also: INTRODUCTION