NIOSH Pocket Guide to Chemical Hazards

Tetramethyl lead (as Pb) CAS 75-74-1
Pb(CH3)4 RTECS TP4725000
Synonyms & Trade Names
Lead tetramethyl, Tetramethylplumbane, TML
DOT ID & Guide
Exposure
Limits
NIOSH REL: TWA 0.075 mg/m3 [skin]
OSHA PEL: TWA 0.075 mg/m3 [skin]
IDLH 40 mg/m3 (as Pb) Conversion
Physical Description
Colorless liquid (unless dyed red, orange, or blue) with a fruity odor. [Note: Main usage is in anti-knock additives for gasoline.]
MW: 267.3
BP: 212°F (Decomposes)
FRZ: -15°F
Sol: 0.002%
VP: 23 mmHg
IP: 8.50 eV

Sp.Gr: 2.00
Fl.P: 100°F
UEL: ?
LEL: ?

Class II Combustible Liquid: Fl.P. at or above 100F and below 140F.
Incompatibilities & Reactivities
Strong oxidizers such as sulfuryl chloride or potassium permanganate
Measurement Methods
NIOSH 2534
Personal Protection & Sanitation
Skin: Prevent skin contact (>0.1%)
Eyes: Prevent eye contact
Wash skin: When contaminated (>0.1%)
Remove: When wet or contaminated (>0.1%)
Change: Daily
Provide: Quick drench (>0.1%)
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH/OSHA
Up to 0.75 mg/m3: (APF = 10) Any supplied-air respirator
Up to 1.875 mg/m3: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode
Up to 3.75 mg/m3: (APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode/(APF = 50) Any self-contained breathing apparatus with a full facepiece/(APF = 50) Any supplied-air respirator with a full facepiece
Up to 40 mg/m3: (APF = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode
Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure- demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Insomnia, bad dreams, restlessness, anxious; hypotension; nausea, anorexia; delirium, mania, convulsions; coma
Target Organs central nervous system, cardiovascular system, kidneys
See also: INTRODUCTION