NIOSH Pocket Guide to Chemical Hazards

o-Toluidine CAS 95-53-4
CH3C6H4NH2 RTECS XU2975000
Synonyms & Trade Names
o-Aminotoluene, 2-Aminotoluene, 1-Methyl-2-aminobenzene, o-Methylaniline, 2-Methylaniline, ortho-Toluidine
DOT ID & Guide
1708 153
Exposure
Limits
NIOSH REL: Ca [skin] See Appendix A
OSHA PEL: TWA 5 ppm (22 mg/m3) [skin]
IDLH Ca [50 ppm] Conversion 1 ppm = 4.38 mg/m3
Physical Description
Colorless to pale-yellow liquid with an aromatic, aniline-like odor.
MW: 107.2
BP: 392°F
FRZ: 6°F
Sol: 2%
VP: 0.3 mmHg
IP: 7.44 eV

Sp.Gr: 1.01
Fl.P: 185°F
UEL: ?
LEL: ?

Class IIIA Combustible Liquid: Fl.P. at or above 140F and below 200F.
Incompatibilities & Reactivities
Strong oxidizers, nitric acid, bases
Measurement Methods
NIOSH 2002, 2017; OSHA 73
Personal Protection & Sanitation
Skin: Prevent skin contact
Eyes: Prevent eye contact
Wash skin: When contaminated
Remove: When wet or contaminated
Change: No recommendation
Provide: Eyewash, Quick drench
First Aid (See procedures)
Eye: Irrigate immediately
Skin: Soap wash immediately
Breathing: Respiratory support
Swallow: Medical attention immediately
Respirator Recommendations NIOSH
At concentrations above the NIOSH REL, or where there is no REL, at any detectable concentration: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode/(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus
Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canister/Any appropriate escape-type, self-contained breathing apparatus
Exposure Routes inhalation, skin absorption, ingestion, skin and/or eye contact
Symptoms Irritation eyes; anoxia, headache, cyanosis; lassitude (weakness, exhaustion), dizziness, drowsiness; micro hematuria (blood in the urine); eye burns; dermatitis; [potential occupational carcinogen]
Target Organs Eyes, skin, blood, kidneys, liver, cardiovascular system

Cancer Site [bladder cancer]
See also: INTRODUCTION