The Graduate Seminar meets Tuesdays 4 - 5 PM in Room 605 of the Biomed Center.
Remember to e-mail a question to this week's presenter by Monday the day before their seminar.

Seminar Schedule

November 21 — Transcription

Presenters: Matthew Riolo

Paper: A. Verdel, S. Jia, S. Gerber, T. Sugiyama, S. Gygi, S.I.S. Grewal and D. Moazed (2004) RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303: 672-676.

November 28 — RNA Processing

Presenters: Haley Menard

Paper: Bleichert et al (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. PNAS 103: 9464-9469.

December 5 — No Seminar

There will be no seminar this week.

 

Previous Seminars:

September 12 — Introduction

Presenter: Ken Miller

Paper: Gaietta, Deerinck, Adams, Bouwer, Tour, Laird, Sosinsky, Tsien, & Ellisman (2002) Multicolor and Electron Microscopic Imaging of Connexin Trafficking. Science 296: 503-507.

September 19 — Membranes

Presenter: Mario Jiz

Paper: Douglass, & Vale (2005) Single-Molecule Microscopy Reveals Plasma Membrane Microdomains Created by Protein-Protein Networks that Exclude or Trap Signaling Molecules in T Cells. Cell 121: 937-950..

September 26 — The Golgi

Presenters: Adrian Reich (Adrian_Reich@brown.edu)

Paper: Axelsson & Warren (2004) Rapid, Endoplasmic Reticulum-independent Diffusion of the Mitotic Golgi Haze. Mol. Biol. Cell 15: 1843-1852.

October 3 — Junctions or Organelles

Presenters: Sam McNeal (Sam_McNeal@brown.edu)

Paper: Spees et al (2006) Mitochondrial transfer between cells can rescue aerobic respiration. PNAS 103: 1283-1288.

October 10 — Cell Cycle

Presenter: Chang Yao

Paper: Holway et al (2006) Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos. JCB 172: 999-1008.

October 17 — Extracellular Matrix

Presenters: Jing Lu & Sabrina Puckett

Paper: Reverte et al (2006) Perturbing integrin function inhibits microtubule growth from centrosomes, spindle assembly, and cytokinesis. JCB 174: 491-497.

October 24— The Genome

Presenters: Kate Heflin & Meredith Crane

Paper: Lin, Dion and Wilson (2006) Transcription promotes contraction of CAG repeat tracts in human cells. Nature Structural and Molecular Biology 13: 179-180. (please review the supplemental material).

October 31 — Johannes Walter

Presenters: Kevin Alby

Paper: Arias & Walter (2005) PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication. Nature Cell Biology 8: 84-90.

November 7 — Contromeres / Telomeres

Presenters: Maureen McCamley

Paper: A. Taggart, S.-C. Teng and V.A. Zakian (2002) Est1p as a cell cycle-regulated activation of telomere-bound telomerase. Science 297: 1023-1026.

November 14 — Ted Salmon

Presenters: Viet Le

Paper: AP Joglekar et al (2006) Molecular architecture of a kinetochore-microtubule attachment site. Nature Cell Biology 8: 581-585