Lecture
Slides available via WebCT
(Note: Slides
will be available with 24 hours of lecture)

Required
Reading:
Textbook:
Alberts et al (2002) Molecular Biology of the Cell. pp. 207-216,
222-226
T.
Jenuwein and C.D. Allis (2001) Translating the histone code.
Science 293: 1074-1080.
B.A.
Leibovitch, Q. Lu, L.R. Benjamin, Y. Liu, D.S. Gilmour and S.C.R. Elgin
(2002) GAGA ffactor and the TFIID complex collaborate in generating
an open chromatin structure at the Drosophila melanogaster hsp26 promoter.
Molec. Cell. Biol. 22: 6148-6157.
R.
Allshire (2002) RNAi and heterochromatin - a hushed-up affair.
Science 297: 1818-1819.
S.C.R.
Elgin and S.I.S. Grewal (2003) Heterochromatin: silence is golden.
Curr. Biol. 13: R895-R898.
A.
Verdel, S. Jia, S. Gerber, T. Sugiyama, S. Gygi, S.I.S. Grewal and D.
Moazed (2004) RNAi-mediated targeting of heterochromatin by
the RITS complex. Science 303: 672-676.