Lecture
Slides available via WebCT
(Note: Slides
will be available with 24 hours of lecture)
Required
Reading:
Textbook:
Alberts et al (2002) Molecular Biology of the Cell. pp. 1065-1080.
Furuse
et al (2001) Conversion of Zonulae Occludentes from Tight to
Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney
I Cells JCB 153: 263-272.
Furuse
et al (2002) Claudin-based tight junctions are crucial for the
mammalian epidermal barrier: a lesson from claudin-1deficient
mice J. Cell Biol. 156: 1099-1111.
Bukauskas
et al (2000) Clustering of connexin 43-enhanced green fluorescent
protein gap junction channels and functional coupling in living cells.
PNAS 97: 2556-2561.
Richards
et al (2004) Protein kinase C spatially and temporally regulates
gap junctional communication during human wound repair via phosphorylation
of connexin43 on serine368. JCB 167:, 555-562.
Takeichi
(2006) Shoichiro Tsukita: a life exploring the molecular architecture
of the tight junction. JCB 172: 321-323.