Table I - HPV Vaccines in Development
Vaccine Name (type) |
Company |
HPV Subunits or Mechanisms |
Adjuvant |
Stage of Research |
| TA-HPV (live recombinant vaccinia virus) | Cantab | E6 and E7 genes from HPV types 16 and 18 | Alum | Phase I/II |
| TA-GW (recombinant protein) | Cantab | L2 and E7 proteins from HPV type 6 | Alhydrogel (type of alum) | Phase IIa |
| MEDI-501 (recombinant VLP vaccine) | MedImmune | L1 protein from HPV type 11 | Alum | Phase I |
| (Quadrivalent recombinant VLP vaccine) | Merck | Undisclosed (?L1) protein from HPV types 6, 11, 16, and 18 | Alum | Phase I trials planned |
| (Naked plasmid DNA) | Merck | Under development | Under development | Preclinical |
| GENEVAX HPV (plasmid DNA) | Apollon | Under development | Under development | Preclinical |