Hepatitis B

Transmission:

 

         Bloodborne

         Sexual

         Perinatal

 

Hepatitis B Virus (HBV) is transmitted by having direct contact with the blood or body fluids of an infected person; for example, one can become infected by having sex or sharing needles with an infected person. A baby can get hepatitis B from an infected mother during childbirth.

 

Clinical Features:

 

         Symptomatic - Jaundice, fatigue, abdominal pain, loss of appetite, intermittent nausea, vomiting.

         Asymptomatic - An estimated 50% of individuals in the U.S. infected with HBV show none of the above symptoms of disease.

( Centers for Disease Control Hepatitis B Page)

 

HBV can cause infection at any age. It may lead to chronic infection of the liver and serious disease, especially if it is acquired during infancy or childhood. However, a child may not show signs of infection until years later when he or she develops liver failure and/or liver cancer. (http://www.health.state.ri.us/disprev/communicable/hepa_b.htm)

 

High Risk Groups:

 

         Injection drug users

         Sexually active heterosexuals

         Men who have sex with men

         Infants/children of immigrants from disease-endemic areas

         Low socioeconomic level

         Sexual/household contacts of infected persons

         Infants born to infected mothers

         Health care workers

         Hemodialysis patients (Centers for Disease Control Hepatitis B Page)

 

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This web site was developed by undergraduate students at Brown University as a project for a course in vaccine development (Bio 160). An effort has been made to present information on the prevalent opinions available at this time.  References to published articles and acknowledgements of other sources are cited in the text.  The authors of this web site are not certified medical professionals.  Biomedical research and clinical medicine are constantly evolving fields, thus it is possible that significant advances in research and treatments will come into existence following posting of this web site.