[1] Halioua B and Malkkin J E. Epidemiology of Gential Herpes -Recent Advances. Eur. J. Dermatol. 1999
         (Apr-May);9[3] 177-184.
    [2] Corey L and Handsfield H H. Gential Herpes and Public Health: Affressing a Global Problem. JAMA 2000 (Feb);
          283[6] 791-794.
    [3] Scopp,Irwin Walter.  Oral Medicine: A Clinical Approach with Basic Science Correlation 1969; 87-89
    [4] Mikloska Z, Danis V A, Adams S, Lloyd A R, Adrian D L, and Cunningham A L. In Vivo Production of Cytokines
          and Beta (C-C) Chemokines In Human Recurrent Herpes Simplex Lesions- Do Herpes Simplex Virus - Infested
          Keratinocytes Contribute To Their Production? JID 1998;177(April) 827-838.
    [5] Darby M L and Bushee E J. Mosby's: Comprehensive Review Of Dental Hygiene.Second Edition 1991; 207-208,
          258, 268-269.
    [6] Rafttery M J, Behrens C K, Muller A, Krammer P H, Walczak H, and Schonrich G. Herpes Simplex Virus Type I
          Infection of Activated Cytotoxic T Cells: Induction of Fratricide as a Mechanism of Viral Immune Evasion. J. Exp.
          Med. 1999;190[8] 1103-1113.
    [7] Hsiung G D, Diagnostic Virology: An Illustrated Handbook. Revised and Enlarged Edition. 1973;127-137.
    [8] Ackermann H W and Berthiaume L. Atlas of Virus Diagrams. CRC Press. 36-41.
    [9] Ackermann H W, Berthiaume L, and Tremblay M. Virus Life in Diagrams. CRC Press 1998; 50-59.
  [10] MazzoneH M. CRC Handbook of Viruses: Mass Molecular Weight Values and Related  Properties. CRC Press. 149.
  [11] Fields B N, Knipe D M, et al. Fundamental Virology-2nd Edition 1991; 7-93, 219-272, 841-899.
  [12] Nicola A V, Willis S H, Naidoo N N, Eisenberg R J, and Cohen G H. Structure-Function Analysis of Soluable
          Forms of Herpes Simplex Virus Glycoprotien D. J. Virol.1996(March);3815-3822.
  [13] Avitable E, Ward P L, Lazzaro C D, Torrisl M R, Roizman B, and Campadelli-Fiume G. The Herpes Simplex UL20
          Protein Compensates for the Differential Disruption of Exocytosis of Virions and Viral Membrane Glycoproteins
          Associated with Fragmantation of the Golgi Apparatus. J. Virol. 1994 (July);7397-7405.
  [14] Roller R J and Herold B C. Characterization of a BHK (TK-) Cell Clone Resistant to Postattachment Entry by
         Herpes Simplex Virus Types 1 and 2. J. Virol. 1997 (May);5805-5813.
  [15] Tal-Singer R, Peng C, Ponce De Leon M, Abrams W R, Banfield B W, Tufaro F, Cohen G H, and Eisenberg R J.
          Interaction of Herpes Simplex Virus Glycoprotein gC with Mammalian Cell Surface Molecules. J. Virol. 1995 (July);
          4471-4483.
  [16] Mikloska Z and Cunningham A L. Herpes Simplex Virus Type 1 Glycoproteins gB, gC and gD are Major Targets for
         CD4 T-Lymphocyte Cytotoxicity in HLR-DR expressing Human Epidermal Keratinocytes. J. Gen.Virol. 1998;79,
         353-361.
  [17] Koelle D M, Corey L, Burke R L, Eisenberg R J, Cohen G H, Pichyangkura R, and Triezenberg S J. Antigenic
          Specificities from Recurrent Gential Herpes Simplex Virus Type 2 Lesions. J. Virol. 1994 (May); 2803-2810.
  [18] Kuby J. Immunology - 3rd Edition 1997; 374-375, 328, 336-352, 318-320.
  [19] Walker J and Leib D A. Protection from Primary Infection and Establishment of Latency by Vaccination with Herpes
          Simplex Virus Type I Recombinant Deficient in the Viron Host Shutoff (vhs) Function. Vaccine 1998; 16[1], 1-5.
  [20] Neumann L, Krass W, Uebel S, Jung G, and Tampe R. The Active Domain of The Herpes Simplex Virus Protien
          ICP47: A Potent Inhibitor of The Transporter Associated with Antigen Processing (TAP). J. Mol. Biol. 1997; 272,
          484-492.
  [21] Galocha B, Hill A, Barnett B C, Dolan A, Raimondi A, Cook R F, Brunner J, McGeoch, and Ploegh L. The
          Active Site Of  ICP47, a Herpes Simplex Virus - Encoded Inhibitor of the Major Histocompatibility Complex
          (MHC)-encoded Peptide Transporter Associated with Antigen Processing (TAP), Maps of the NH(2)-terminal 35
          Residues. J. Exp. Med. 1997(May);185[9], 1565-1572.
  [22] Freidman H M, Wang L, Fishman N O, Lambris J D, Eisenberg R J, Cohen G, and Lubinski J. Immune Evasion
          Properties of Herpes Simplex Virus Type I Glycoprotein gC. J. Virol. 1996 (July); 4253-4260.
  [23] Nagashunmugam T, Lubinski J, Wang L, Goldstein L T, Weeks B S, Sundaresan P, Kang E H, Dubin G, and Friedman
          H M. In Vivo Immune Evasion Mediated by the Herpes Simplex Virus Type I Immunoglobulin G Fc Receptor. J. Virol.
          1998 (July); 5351-5359.
  [24] Stanberry L R. Control of STDs--the Role of Prophylactic Vaccines against Herpes Simplex Virus. Sex Transm. Inf.
         1998;74, 391-394
  [25]  http://ashastd.org/herpes/hrc/educate.html
  [26]  http://www.henderson-morley.com/research/skinner.html
  [27]  http://www.henderson-morley.com/research/skinner.html
  [28]  http://www.homestead.com/HerpesNews/skinnervaccine.html
  [29]  http://www.newsfile.com/homepage/092898pr.htm#A5
  [30]  http://www.homestead.com/HerpesNews/LupidonVaccine.htmlSame as 29 both shoppers
  [31]  http://dyred.sureste.com/herpes/
  [32]  http://www.niaid.nih.gov/factsheets/herpesvac.htm
  [33]  http://www.reach4life.com/lysine.html
  [34]  http://herpes.com/Treatment.shtml
  [35]  Vaccine table & PREPS --http://www.henderson-morley.com/research/vaccine.html
  [36]  Cervix photo--http://www.herpes.org.nz/prgen.html
  [37]  Whitlow --http://www.herpes.org.nz/prbody.html
  [38]   Ear, labial, neck--http://www.herpes.org.nz/presentations.html New Zealand herpes foundation
  [39]   Ocular-foot , superior labialis thumb http://ades.tmc.edu.tw/English/pcare/course/herpes_simplex/
  [40]   Facial--http://tray.dermatology.uiowa.edu/HSV-001.htm
  [41]   Electron images +  Spot-scan Electron Cryomicroscopy  -- 3-D representation of HSV-1 capsid. Reproduced with
            permission from "Structural Biology of DNA-Containing Viruses," on the World Wide Web:
            (http://www.bcm.tmc.edu/molvir/chiu.htm got image and subunits), Copyright
           © Wah Chiu, PhD, University of California, Berkeley.
            http://www.medscape.com/SCP/IIM/1997/v14.n03/m2290.hanissian/m2290.hanissian.html
  [42]  Perng G-C,Slanina S M, Yukht A, Drolet B S, Keleher Jr. W,Ghiasi H, Nesburn A B, and Wechsler S L. A
           Herpes Simplex Virus Type 1 Latency Associated Transcript Mutant with Increased Virulence and Reduced
           Spontanous Reactivation. J. Virol. 1999(Feb); 73[2], 920-929
  [43]  White D O and Fenner F J. Medical Virology: Fourth Edition 1994; 19,
  [44]  http://www.opt.pacificu.edu/opt/viral/hsvgen.htm
  [45]  Bearer E L, Breakefield X O, Schuback D, Reese T S, and LaVail. Retrograde Axonal Transport of Herpes Simplex
           Virus:  Evidence for a Single Mechanism and a Role for Tegument; Unpublished. Dept. of Pathology and Laboratory
           Medicine, Brown University.
  [46]  Manns. Viruses and Autoimmune Liver Disease. MPIntervirology 1993;35(1-4):108-15.
  [47]  Fields B N, Knipe D M, Howley P M. Reviewed in Riozman and Sears, Fields Virology [Third Edition]. Eds.,
           Lippencott-Raven, Philiadelphia, 1996; 2231-2295.

  {48]  Drawings of HSV Genital locations --http://www.herpes.org.nz/doihavegh.html\
   [49]  Herpes Whitlow Blue back Photo --http://tray.dermatology.uiowa.edu/DIB/HSV-002.htm
   [50]  Palm Hand Photo --http://tray.dermatology.uiowa.edu/DIB/HSV-004.htm
   [51]  Congenital baby Photo --http://tray.dermatology.uiowa.edu/HSVCon01.htm
   [52]  Congenital  Photo-- http://tray.dermatology.uiowa.edu/HSVCon02.htm
   [53]  Congenital Photo-- http://tray.dermatology.uiowa.edu/HSVCon05.htm
   [54]  Hsv movie on Desk top.  Herpesvirus (entire particle) solved by cryo-electron microscopy and image
            reconstruction    http://www.bocklabs.wisc.edu/herpescapsid.html
   [55]  Vaginal HSV2 Photo -- http://www.homestead.com/HerpesNews/HerpesPictures.html
   [56]  Duke University  Photo --http://www.duke.edu/~clark026/main.html
   [57]  Electron micro 2  Photo--
            http://www.ozemail.com.au/~iusti/images/cd-rom/herpes02-electron%20microsocopic%20picture%20of%20hsv.jpg
   [58]  March of Dimes   Photo  http://noah.cuny.edu/pregnancy/march_of_dimes/stds/herpesis.html
   [59]  Genital Herpes Photos-- www.
   [60]  Feyzi E, Trybala E, BergstrÖm T, Lindahl U, and Spillman D. Structural Requirement of Heperin Sulfate for
            Interaction with Herpes Simplex Virus Type 1 Virions and Isolated Glycoprotein C-*. JBC Online
            1997;272(40):24850.
   [61]  Perng G-C, Slainina S M, Yukht A, Drolet B S, Keleher Jr. W, Ghiasi H, Nesburn A B, and Wechsler S L. A Herpes
            Simplex Virus Type 1 Latency-Associated Transcript Mutant with Increased Virulence and Reduced Spontaneous
            Reactivation. J. Virol Online 1999 (Feb); 73 (2): 920-929.
   [62]  Koelle D M, Frank J M, Johnson M L and Kwok W W. Recogniton of Herpes Simplex Virus Type 2 Tegument
            Proteins by CD4 T Cells Infiltrating Human Genital Lesions. J. Virol. 1998 (Sept.); 72[9]: 7476-7483.
   [63]  Jerome K R, Tait J F, Koelle D M and Corey L. Herpes Simplex Virus Type 1 Renders Infected Cells Resistant to
            Cytotoxic T-Lymphocyte-Induced Apoptosis. J. Virol.1998 (Jan). 72[1]: 436-441.
   [64]  Aurelian L, Kokuba H and Smith C C. Vaccine Potential of a Herpes Simplex Virus Type 2 Mutant Deleted in the PK
            Domain of the Large Subunit of Ribonucleotide Reductase (ICP10). Vaccine1999;17: 1951-1963.
   [65]  Lubinski J M, Wang L, Soulika A M, Burger R, Wetsel R A, Colten G H, Eisenberg R J, Lambris J D and Freidman
            H M. Herpes Simplex Virus Type 1 Glycoprotein gC Mediates Immune Evasion In Vivo. J Virol. 1998 (Oct);72[10]:
            8257-8263.
   [66]  Bernstein D I and Stanbery L R. Herpes Simplex Virus Vaccines. Vaccine 1999; 17: 1681-1689.
   [67]  Ghiasi H, Nesburn A B and Wechsler S L. Vaccination with a Cocktail of Seven Recombinatly exjpressed HSV-1
            Glycoproteins protects against Ocular HSV-1 Challenge More Efficiently than Vaccination with any Individual
            Glycoprotein. Vaccine 1996; 14[2]: 107-112.
   [68]  Rosenthal K S, Mao H, Horne W I, Wright C and Zimmerman D. Immunization with a LEAPS(TM)
            Heteroconjugate Containing a CTL Epitope and a Peptide from Beta-2-microglobulin Elicits a Protective and DTH
            Response to Herpes Simplex Virus Type 1. Vaccine 1999; 17: 535-542.
   [69]  Bernstein D. Effect of Route of Vaccination with Vaccinia Virus Expressing HSV-2 Glycoprotein D on Protection from
            Genital HSV-2 Infection. Vaccine 2000; 18: 1351-1358
   [70]   O'Hagen D, Goldbeck C, Ugozzoli M, Ott G and Burke. Intranasal Immunization with Recombinant gD2 Reduces
            disease Severity and Mortality Following Genital Challenge with Herpes Simplex Virus Type 2 in Guinea Pig Models.
            Vaccine 1999; 17: 2229-2236.
    [71]  Corey L and Handsfield H H. Genital Herpes and Public Health: Addressing a Global Problem. JAMA 2000 (Feb
            9);283[6]:791-4.
    [72]  Langenberg A G, Corey L, Ashley R L, Leong W P and Straus S E. A Prospective Study of New Infections with
            Herpes Simplexvirus Type 1 and 2. Chiron HSV Vaccine Study Group. N Engl J Med 1999(Nov); 341[19]:
            1432-1438.
    [73]  Benencia F and Courreges M C. Antiviral Activity of Sandalwood Oil Against Herpes Simplex Viruses-1 and-2.
            Phytomedicine 1999 (May);6[2]:119-123.
    [74]  Hashido M and Kawana T. Herpes Simplex Virus-Specific IgM, IgA and IgG Subclass Antibody Responses in
            Primary and Nonprimary Genital Herpes Patients. Microbiol Immunol 1997; 41[5]:415-420.
    [75]  Ghiasi H, Hofman F M, Cai S, Perng G-C, Nesburn A B and Wechsler S L. Vaccination with Different HSV-1
            Glycoproteins Induces Different Patterns of Ocular Cytokine Responses Following HSV-1 Challenge of Vaccinated
            Mice. Vaccine 1999;17: 2576-2582.
    [76]  Hedner E, Vahlne A, Kahnberg K E and Hirsch J M. Reactivated Herpes Simplex Virus Infestion as a Possible
            Cause of Dry Socket After Tooth Extraction. J Oral Maxillofac Surg. 1993 (Apr); 51[4]: 370-378.
    [77]  Belshe R B. Textbook of Human Virology.PSG Publishing Company,Inc. 1994: 811-821.
    [78]  Domingo E, Webster R and Holland J. Origin and Evolution of Viruses. ACADEMIC PRESS 1999.
    [79]  White D O and Fenner F J. Medical Virology: Fourth Edition. ACADEMIC PRESS 1994.19-38,91-272, 317-347.
    [80]  Booy F P, Newcomb W W, Trus B L, Brown J C, Baker T S and Steven A C. Liquid-Crystalline,Phage-like
            Packing of Encapsidated DNA in Herpes Simplex Virus. CELL  1991 (March 8); 64:1007-1015.
    [81]  Glorioso J C, DeLuca N A and Fink D J. Development and Application of Herpes Simplex Virus Vectors for
            Human Gene Therapy. Annu. Rev. of Microbiol. 1995; 49: 675-710.
    [82]  Tortora G J. Principles of Human Anatomy: Sixth Edition.  HarperCollins Publishers 1992.96,463.

      Epidemiology / Pathogenesis / Mode_of_Infection / Immune_Response / Immune_Evasion /
       Pathologies / Treatment / Genetics / Vaccines / Photos / References / Links / HSV Home