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photo taken from Fields Virology (4) |
Home Introduction Epidemiology Mode of Infection Virology Pathogenesis Vaccine
Introduction
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Rubella, also
known as German measles, is characterized by temperate constitutional symptoms,
a low-grade fever, and a widespread rash of pink-red spots . The rash initially
appears on the face and upper trunk but extends over the entire body within
a day. Additionally, the occipital, postauricular, and cervical nodes become
swollen and tender, especially in adolescents and young adults. An infected
individual may also experience tender, bleeding gums and transient polyarthralgia
or arthritis as part of his/her illness. Postnatal rubella is rather mild
and complete recovery can be expected in 3 to 4 days. Treatment is usually
unnecessary; however, most children are first vaccinated at 12 to 15 months
of age with the MMR vaccine.(7)
Congenital
rubella is more serious. Infants can suffer from ophthalmologic, cardiac,
auditory, and neurological difficulties. Other clinical manifestations
include growth-retardness, radiolucent bone disease, and purple skin lesions.
Additionally, infected pregnant mothers can suffer from stillbirths and
abortions, and the infant frequently suffers from many of these congenital
anomalies. Due to the licensing of live attenuated rubella vaccines, congenital
rubella can be prevented.(5)
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