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Outline |
| A | Website project | Project: A website, developed according to guidelines developed by course leaders and webmaster, that proceeds as follows: (1) identify subject. (2) background reading. (3) write text according to website structure. (4) collect or create illustrations. (5) write HTML. (6) request evaluation by webmaster and faculty. (7) post site. (8) report to class. Evaluation by class and faculty. | =1/3 Grade (alternate for B) |
| B | Community-based vaccine project | Project: A community-based, vaccine related project that proceeds as follows: (1) identify question. (2) background investigations. (3) identify community site. (4) request permissions. (5) perform data collection. (6) analyze results. (7) write report. (8) report to class. Evaluation by class and faculty. | =1/3 Grade (alternate for A) |
| C | Term Paper | A grant proposal: 15 pages maximum, excluding bibliography & figures/tables. Proposal must contain the following components: (1) Abstract and Specific Aims. (2) Background: review of the literature (Epidemiology, Pathogenesis, Correlates of immunity, Current vaccines). (3) Proposal and justification. (3) Research Plan: steps to develop vaccine: experimental design. (4) Timeline | =1/3 Grade |
| Class Participation | Attendance / participation in discussions of course topics and student presentations. | =1/3 Grade |
Lecture Schedule
Handouts & Lecture notes are in PDF format. You will need
Adobe Acrobat to be able to view them. Acrobat is available off the
Applications server or by clicking here.
| Date | Abs | Topic | Speaker | Conf | Alternate | Handouts | ||
| Weds | 26-Jan-00 | Introduction | Introduction, Requirements for Grade | P. Knopf, A. De Groot | Y | Outline / Reserves | ||
| Fri | 28-Jan-00 | ADG | Website tour | P. Knopf, Kevin Dallas | Y | Web Choices | ||
| Monday | 31-Jan-00 | ADG | Introduction | Over View of Immune Responses | Paul Knopf | Y | ||
| Weds | 02-Feb-00 | Vaccine Strategies | Pathogens from A to Z | Steve Opal | Y | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy |
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| Fri | 04-Feb-00 | Screening | Screening: "Outbreak" | office hours | ||||
| Monday | 07-Feb-00 | Framework | Smallpox, Polio, Ebola, West Nile Virus, and Beyond | Anne De Groot | Y | Project Groups | ||
| Weds | 09-Feb-00 | ADG | Vaccine Strategies | Antibodies and Host Defense (Part 1) | P. Knopf | Y | ||
| Th | optional seminar | ADG | Immunology/Pathology | 4PM Eddy | ||||
| Fri | 11-Feb-00 | ADG | Vaccine Strategies | Antibodies and Host Defense (Part 2) | P. Knopf | Aksoy Petzke Reserves | ||
| Monday | 14-Feb-00 | Vaccine Strategies | Cell mediated immunity and Host Defense | * Judy Lieberman | Y | A. De Groot | ||
| Weds | 16-Feb-00 | Vaccine Strategies | Vectors (flies, mosquitoes, ticks) | Serap Aksoy/Yale U. | Y | |||
| Th | optional seminar | Immunology/Pathology | Macrophage Apoptosis and Innate Immunity to Tuberculosis | Hardy Kornfeld /Boston U. | ||||
| Fri | 18-Feb-00 | Website | Intro to HTML / Tips for web project formats | Kevin Dallas | Y | |||
| Monday | 21-Feb-00 | all | long weekend | long weekend-no class | ||||
| Weds | 23-Feb-00 | all | Vaccine Strategies | Mucosal Immunity | Mary Petske/Harvard | Y | reserves | |
| Th | optional seminar | ADG | Immunology/Pathology | 4PM Eddy TBA | ||||
| Fri | 25-Feb-00 | Screening/Office/Website | TBA | office hours | ||||
| Monday | 28-Feb-00 | ADG | Illustrated Vaccines | Rotavirus/Where do we go from here? | Penny Dennehey | Y | ||
| Weds | 01-Mar-00 | Illustrated Vaccines | TB: Global Emergency | A. De Groot | Y | Attachment1
Attachment2 Attachment3 |
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| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 03-Mar-00 | Screening/Office/Website | TBA | office hours | ||||
| Monday | 06-Mar-00 | Illustrated Vaccines | HIV: Virus, Host, and Vaccine | * Janet McNicholl, CDC | Y | |||
| Weds | 08-Mar-00 | Illustrated Vaccines | Clinical Vaccinology: Gen'l Principles & Case Studies | Georges Peter | Y | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 10-Mar-00 | Screening/Office/Website | TBA | office hours | ||||
| Monday | 13-Mar-00 | Vaccine Strategies | Cancer: HPV | Michael Steller | Y | |||
| Weds | 15-Mar-00 | Illustrated Vaccines | Cancer: Hematologic (leukemia) | Loren Fast | Y | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 17-Mar-00 | Begin Student web/project | TBA | office hours | ||||
| Monday | 20-Mar-00 | ADG | Student web/project | Student Presentations 1-2-3 | ||||
| Weds | 22-Mar-00 | ADG | Student web/project | Student Presentations 4-5-6 | TV Rajan ??? | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 24-Mar-00 | Student web/project | Student Presentations 7-8-9 AND HAND IN TWO PAGE OUTLINE OF PAPER | |||||
| Monday | 27-Mar-00 | all | break | |||||
| Weds | 29-Mar-00 | all | break | - | ||||
| Th | optional seminar | all | break | - | ||||
| Fri | 31-Mar-00 | all | break | - | ||||
| Monday | 03-Apr-00 | Illustrated Vaccines | Hepatitis B: Cost vs Conquest | * Fred Prince | Y | |||
| Weds | 05-Apr-00 | Illustrated Vaccines | Hepatitis C: Prevention or Therapy? | Jack Wands | Y | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 07-Apr-00 | Student web/project | Student Presentations 10-11-12 | |||||
| Monday | 10-Apr-00 | Illustrated Vaccines | TBA: Bench to Market | Debra Peattie | I | |||
| Weds | 12-Apr-00 | Illustrated Vaccines | Hookworm & Schistosome Vaccine Development | Rick Bungiro | Y | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 14-Apr-00 | Student web/project | Student Presentations 13-14-15 | |||||
| Monday | 17-Apr-00 | Illustrated Vaccines | TBA (diarrheal disease/Bangladesh or Malaria) | |||||
| Weds | 19-Apr-00 | Future Therapy | Sepsis: Vaccines to prevent Sudden Death | S. Opal | Y | |||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 21-Apr-00 | Student web/project | TBA | office hours | ||||
| Monday | 24-Apr-00 | Future Therapy | Evolution in a Test tube | *R.Whalen/MaxygenInc. | I | |||
| Weds | 26-Apr-00 | Future Therapy | Designer Vaccines | A. De Groot | ||||
| Th | optional seminar | Immunology/Pathology | 4PM Eddy TBA | |||||
| Fri | 28-Apr-00 | ??? | office hours | |||||
| Monday | 01-May-00 | ADG | Term Papers Due / Seniors | FIELD TRIP TO WASHINGTON DC/ VACCINE MEETING | ||||
| Weds | 03-May-00 | ADG | Term Papers Due / Nonseniors |