Transient abnormal myelopoesis: Down Syndrome



The white blood count of this trisomy 21 newborn was markedly elevated. The blood smear shows (from left to right) abundance

of white blood cells; two blasts and two large platelets; two blasts, a myelocyte, and a metamyelocyte; an abnormal binucleate

red blood cell. This clinical picture raises the question of leukemia but these abnormalities resolve within a few weeks.



1 minute clinical correlation

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