Rocky Mountain Spotted Fever

 

Infection with rickettsial organisms such as Rickettsia rickettsii produce a hemorrhagic rash and hemorrhages in many internal organs including the lung (left photo).  The changes are secondary to vasculitis (center photo). The endothelial cells are swollen and there is a mononuclear perivascular innflammation. Mononuclear interstitial pneumonia is seen in the photo on the right.

From the slide collection of the late Dr. Charles Kuhn

 

1 minute clinical correlation

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