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- BIOL 2490A: Nuclear Hormone Receptors
in Growth, Differentiation and Disease
Instructor: Alexander Brodsky
Alexander_Brodsky@brown.edu
Time and Place: Course Schedule
Key developmental and homeostatic hormones such
as steroid hormones (e.g. estrogen, testosterone,
glucocorticoids), and lipophilic non-steroids (e.g.
retinoic acid, thyroid hormone) act through receptors
that directly bind DNA and control gene expression.
This course examines the activities, structures,
functions, and mechanisms of action of these Nuclear
Hormone Receptors and the consequences of alterations
in protein or hormone function. Approaches span
genetics, biochemistry, genomics, proteomics, and
developmental biology. For more information view the Course Catalog.
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