|
|
Postdoctoral Fellow Fabio Vandin and PhD candidate Derek Aguiar win Travel Awards for the RECOMB 2010
August 2010
|
August 2010
Lisbon, Portugal
Postdoctoral Fellow Fabio Vandin and PhD candidate Derek Aguiar win Travel Awards for the RECOMB 2010 where they presented their papers. The Annual International Conference on Research in Computational Biology -- RECOMB -- is one of the top conferences in computational biology.
Bjarni V. Halldo´rsson, Derek Aguiar, Ryan Tarpine, and Sorin Istrail.
The Clark Phaseable Sample Size Problem: Long-Range Phasing and Loss
of Heterozygosity in GWAS. Journal of Computational Biology,
18(3):323–333, March 2011.
Fabio Vandin, Eli Upfal, and Benjamin J. Raphael. Algorithms for
detecting significantly mutated pathways in cancer. Journal of
Computational Biology, 18(3):507–522, March 2011.
|
RECOMB Satellite Conference
on SNPs and Haplotypes - January 27-28, 2007
|
January 27-28, 2007
University of Southern California
Organized by the
Department of Molecular and Computational Biology,
University of Southern California
http://www.usc.edu/dept/LAS/biosci/mcb/
in collaborations with
the Center for Computational Molecular Biology,
Brown University
http://www.brown.edu/Research/CCMB
University of Southern California, Los Angeles
|
Genome Magazine highlights Ben Raphael's Work
|
January 3, 2007
Genome Technology Magazine Recognizes Ben Raphael as Rising Star
The January 2007 issue of Genome Technology magazine named Center for Computational
Molecular Biology Assistant Professor Ben Raphael to their annual "Tomorrow's PIs"
list.
Raphael received his Ph.D. from the University of California, San Diego in
2002 and joined the Brown faculty in September. In the past year Raphael and his
colleagues published a paper in Genome Research titled, "Decoding the fine-scale
structure of a breast cancer genome and transcriptome." The study demonstrated advantages
of end sequence profiling to map the rearrangements of tumor genomes using the MCF-7
breast cancer cell line; those include the ability to generate tumor-specific reagents
for in vitro and in vivo studies as well as detection of rearrangement and copy
number changes...
Article at Brown CS
|
Center Research featured in Proceedings of
The National Academy
of Sciences (Ben Raphael)
|
December 20, 2006
Evolution, Software, and Microinversions
Biologists will be able to reconstruct
the process of evolution, determine relationships between species and build phylogenetic
trees with greater accuracy thanks to a new method for identifying “microinversions,”
which are extremely short strings of inverted nucleotides. This new work from researchers
at UC San Diego and Brown University appeared in the online edition of the Proceedings
of the National Academy of Sciences (PNAS)...
Article at Brown CS
|
Ben Raphael joins CCMB
|
September 1, 2006
Raphael joins the CCMB after completing a postdoctoral fellowship at the University
of California, San Diego. Prof. Raphael research interests include computational
cancer biology and the design and application of algorithms for problems in
comparative genomics, regulatory genomics, and genetic variation.
He holds a Career Award at the Scientific Interface from the Burroughs
Wellcome Fund, and was the recipient of Alfred P. Sloan Postdoctoral
Fellowship in Computational Molecular Biology.
|
|
Paradigm Shift in RNA Inference
|
June 2006
The "power of sampling" RNA secondary structure pioneered by Professor Lawrence
and colleagues is highlighted in a recent review article in the Journal of Molecular
Biology (J. Mol. Biol. (2006) 359, 526-532). "Recent results show the power of sampling in predicting
regions in an
RNA that are most likely to be accessible to hybridization,
in predicting secondary structures with fewer false positive base-pairs,
and to understanding the folding landscape. The impact of this is
enormous because, for the first time, the set of predicted
secondary structures is a statistical sample of the complete ensemble of structures.
The probability of sampling any given structure is exactly its probability of occurring
in the thermodynamic ensemble".
|
Brown Students present Computational Biology Research
|
May, 2006
Student Poster Day
on Computational Biology
hosted by
Professor Will Fairbrother
The First Annual Computational Biology Poster Session was held in Room 105 of the
Center for Genomics and Proteomics on Friday, May 5th, 2006, from 3:00-5:00pm. Posters
ranged from image processing, to simulation of protein nucleic acid recognition
events, to the development of special alignment tools for non-coding regulatory
elements. It was a great opportunity to meet students and faculty interested in
Computational Biology here at Brown...
|
|
Brown Computational Biology Initiative
|
September, 2003
Endowed by a $20 million gift from a Brown trustee
The Center for Computational Molecular Biology (CCMB) at Brown was founded in September
2003 with the aim of establishing a world-class center for research and scholarship
in this new discipline.
|
|
