ISTRAIL LABORATORY :: BROWN UNIVERSITY
  115 Waterman Street • 5th floor • Box 1910 • Brown University • Providence, RI 02912













Brown University
Department of
Computer Science



Imperfect Ancestral Recombination Graph (iARG) Reconstruction


People: Fumei Lam, Ryan Tarpine, Sorin Istrail

iARG is a collection of tools to reconstruct evolutionary histories which include recombination and back/recurrent mutation events. The algorithms in iARG are based on the Directed Steiner Arborescence Problem and are described in
Imperfect Ancestral Recombination Graph Reconstruction: A Unifying Model Incorporating Back/Recurrent Mutation and Recombination Events by Fumei Lam, Ryan Tarpine, and Sorin Istrail (submitted, 2007)

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Related Links


An imperfect ancestral recombination graph constructed by iARG for the benchmark
Kreitman Drosophila melanogaster data (1983)