ISTRAIL LABORATORY :: BROWN UNIVERSITY
  115 Waterman Street • 5th floor • Box 1910 • Brown University • Providence, RI 02912
 








Brown University
Department of
Computer Science
ISTRAIL LABORATORY PROJECTS

GENOMIC REGULATORY NETWORKS AND THE REGULATORY GENOME
-Cyrene - cis-Lexicon and cis-Browser
-sea urchin developmental gene regulatory networks
-building a high-resolution transcriptome map of the embryo
-inferring logic functions of genomic cis-regulatory code and the principles of information processing of genomic regulation
CELLARIUM: AN INTEGRATED FRAMEWORK FOR GENOME BROWSERS AND BIOINFORMATICS WORKFLOWS
-ROADRUNNER: Bioinformatics Workflow System
-BEAR BROWSERS: Specialized Bioinformatics Browsers and Tools
-VIRTUAL SEA URCHIN: 4-D Map of the Sea Urchin Embryo
-TRANQUILITY: Suite of Computational Biology Tools
COMPUTATIONAL MODELS OF SNPS AND DISEASE ASSOCIATIONS
-HapMap analysis tools design for SNP selection
-Haplotype Phasing
-Genome-wide Disease Associations
MEDICAL BIOINFORMATICS AND BEYOND
-Viral Immunology and Comparative Immunopeptidomics of Humans and their Pathogens
-Rabbit genome project (Genetic determinants of sudden cardiac death)
-Computational Support for Pathology Diagnosis of Cancer
ALGORITHMIC THEORY OF PROTEIN FOLDING AND MISFOLDING
-Lattice Protein Folding Algorithms with mathematically guaranteed Error Bound
-Graph Theory of Self avoiding Walks
-Contact Maps and Protein Structure
-Energy Function Inference pb
-PDB Structure Alignment
STATISTICAL MECHANICS & COMPUTATIONAL COMPLEXITY
-The Rise and Fall of the Search for the Three-Dimensional Exactly Solvable Statistical Mechanics Models
-ISING Models
-Combinatorial Roots of Phase Transition
-Complex Systems & Laws of Complexity & Simplicity
VON NEUMANN RESEARCH PROGRAM IN BIOLOGICAL COMPLEX SYSTEMS
-John von Neumann Page
-continuing John von Neumann's unfinished research program towards a new information
and computation theory for biological complex systems
-information theory and genomics