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Curriculum
Vitae
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|
Anne
Searls De Groot M.D.
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|
 |
|
Date
of Birth: November 20, 1956
Place of Birth: Winchester, MA
Citizenship: United States
Children: Aminata (8) and Zeno (12)
Home: 292 Morris Ave., Providence RI 02906
Office/Lab: TB/HIV Research Laboratory International Health Institute/
BMC 4
Phone: 401.277.3655
Fax: 401.277.3652
Email: Anne_DeGroot@Brown.edu
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Education
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|
| B.A.,
Smith College, Northampton, Massachusetts |
1978
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| M.D.,
Pritzker School of Medicine, University of Chicago |
1983
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| Post-Graduate
Training |
|
|
Internal
Medicine Resident
|
1983-1986
|
Department
of Internal Medicine
Tufts New England Medical Center, Boston MA
|
|
| Fellowship
in Parasitology and Vaccine Research |
1986-1989
|
National
Research Service Award Fellow, National Institutes of Health 1986-1989
Malaria Section, Laboratory of Parasitic Diseases, NIAID (Dr. M. Good)
Metabolism Branch, NCI, National Institutes of Health (Dr. J. Berzofsky)
|
|
| Fellowship
in Infectious Disease |
1989-1992
|
Division
of Geographic Medicine and Infectious Disease, Tufts New England Medical
Center, Boston MA
|
|
| Honors/Awards |
|
| Kraft
Nutrition Fellow: Research on newborn nutrition in Zaire and South Africa
|
1983 |
| National
Research Service Award for malaria and HIV immunology research |
1986-1989 |
| NFID
Eli Lilly Award for TB immunology research |
1991-1992 |
| Visiting
Scholar Award, TMRC, RITM, Manila, The Philippines |
January 1995 |
| Specialty
Boards |
|
| Internal
Medicine |
1987 |
| Infectious
Disease |
1992 |
| Academic
Appointments |
|
|
Clinical Instructor, Department of Medicine |
1989-1991 |
Division
of Geographic Medicine and Infectious Diseases
|
|
|
Special Scientific Staff, Department of Medicine |
1/92-6/92 |
Division
of Geographic Medicine and Infectious Diseases,Tufts New England Medical
Center
|
|
| Assistant
Professor of Medicine and Community Health |
7/92-
12/2000 |
Division
of Biology and Medicine Joint appointment in the Department of Medicine
and the Department of Community Health Brown University School of Medicine
|
|
| Assistant
Professor of Community Health and Medicine |
1/01-
present |
Division
of Biology and Medicine Joint appointment in the Department of Community
Health and the Department of Medicine Brown University School of Medicine
|
|
| Hospital
Appointments |
|
|
Assistant Director, HIV/AIDS Unit, Lemuel Shattuck Hospital |
7/92-6/93
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| Director,
Dual Infection (HIV/TB) Clinic, Lemuel Shattuck Hospital |
5/93-1/94 |
| Medical
Staff, Geographic Medicine, Miriam Hospital, RI |
7/92-present |
| Medical
Staff, (TB clinic) Roger Williams Hospital, Providence RI |
10/93-6/2001 |
| Medical
Staff, Infectious Diseases, (HIV clinic) Memorial Hospital of RI |
7/97-6/2001 |
| TB
Clinic Staff/ Miriam Hospital Rise Clinic (TB Clinic) |
7/2001-present |
| Other
Appointments |
|
|
Director, I.D. (HIV) Clinic for Female Inmates, |
5/92-
1/1/96 |
Massachusetts
Correctional Institution at Framingham (under the Massachusetts Department
of Public Health, and the Shattuck Hospital)
|
|
| Staff,
Rhode Island State TB Clinic (Roger Williams Hospital) |
10/93-present |
| Staff,
HIV in Prisons Program, Yale University (York Institution for Women) |
8/96-present |
| Director,
TB/HIV Research Laboratory, International Health Institute |
7/92-present |
| Chair,
HIV Education Prison Project (Brown AIDS Program) |
1/99-present |
| Founder
and Chief Editor, HIV Education Prison Project News (HEPP News) |
6/99-present |
| Founder
and Scientific Director / GAIA Vaccine Foundation |
5/18/01- |
| Hospital
Committees |
|
| Quality
Assurance, Lemuel Shattuck Hospital |
1991-1992 |
| Academic
Committees |
|
| People's
Health Colloquium, Working group on the |
1992-1993 |
Social
and Community Contexts of Health Care; Brown University School of Medicine
|
|
| Foreign
Research Fellowship Committee, Brown U. Medical School |
1996-1997 |
| Fogarty
ARTP, International Health Institute, Senior Executive Committee |
1996-1998 |
| Other
Committees |
|
| Expert
Panel, Health Status of Soon-to-be-released Inmates Project |
1999 |
National
Commission on Correctional Health Care
|
|
| Advisory
Panel, WHO TB Programme |
1998-2000 |
| Prison
Advisory Panel, National AIDS Minority Council (NMAC) |
2000-present |
| Membership
in Societies |
|
| Massachusetts
Medical Society |
current |
| Massachusetts
Infectious Diseases Society |
current |
| Wayland
Collegium (Brown University) |
current |
| Editor |
|
|
Founder and Chief Editor, HIV Education/Prison Project News |
7/98-present
|
Facsimile-delivered
monthly update on HIV treatment for correctional HIV providers Monthly
circulation: 14,000 subscribers (HIV/ Corrections professionals), by
facsimilie and email. Website http://www.HIVcorrections.org
|
|
| Editor,
AIDS Reader (Prison series) |
2000
- present |
| Guest
Editor, Rhode Island Journal of Medicine (Clinical Trials series) |
Dec
2000 |
| Editor,
Emerging Infectious Diseases |
2001-present |
| Invited
Editor for issue of Methods (Academic Press) |
2002 |
on Bioinformatics
in Vaccine Design
|
|
Publications
(Peer Reviewed) |
|
|
1.
Quakyi IA, Otoo LN, Pombo D, Sugars LY, Menon A, Anne S. De Groot,
Johnson AH, Alling D, Miller LH, and
Good MF,
Differential
nonresponsiveness in humans of candidate Plasmodium
falciparum vaccine antigens,
Am. J. Trop. Med. Hyg., 1989,
Vol. 41, Issue 2, pp. 125-134.
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2.
Anne S. De Groot, Johnson AH, Maloy.WL, Quakyi IA, Riley EM,
Menon A, Banks S M, Berzofsky JA, and Good MF, Human T cell
recognition of polymorphic epitopes from malaria
circumsporozoite protein, J. Immunol., 1989, Vol.142, No.11,
pp. 4000-4005.
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|
| 3.
Good MF, Kumar S, Anne S. DeGroot, Weiss WR, Quakyi IA, Dontfraid F, Smith
FE, Cochran M, Berzofsky JA, Miller LH, Evidence implicating MHC genes
in the immunological nonresponsiveness to the plasmodium falciparum CS protein,
Bulletin of the World Health Organization, 68 Supplement: pp. 80-84,
1990. |
|
| 4.
Anne S. De Groot, Hosmalin CM, Hughes A, Barnd SH, Hendrix D, Houghten CW,
Shearer GM, Berzofsky JA, Human Immunodeficiency Virus Reverse Transcriptase
T Helper Epitopes Identified in Mice and Humans: Correlation with a Cytotoxic
T Cell Epitope, J. Infectious Disease 1991, Vol.164, pp.1058-1065. |
|
| 5.
Meister GE, Roberts CGP, Berzofsky JA, Anne S. De Groot, Two novel T
cell epitope prediction algorithms based on MHC-binding motifs; comparison
of predicted and published epitopes from Mycobacterium tuberculosis and
HIV protein sequences, Vaccine 1995, Vol. 13, No. 6, pp.
581-591. |
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6. Stevens J, Zierler S, Dean D, Goodman AK, Chalfen EM, Anne S. De Groot,
Prevalence of priorsexual abuse and HIV risk-taking behaviors in incarcerated
women in Massachusetts, J. Correctional Health Care, 1995, Vol.
2, Issue 2, pp. 137-149. |
|
| 7.
Stevens J ,Zierler S, Cram V, Dean D, Mayer KH , Anne S. De Groot, Risks
for HIV infection in incarcerated women, J. Women's Health, 1995,
Vol. 4, No. 5, pp. 569-577 |
.
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| 8.
Roberts CGP, Meister GE, Jesdale BM, Lieberman J, Berzofsky JA, Anne S.
De Groot, Prediction of HIV peptide epitopes by a novel algorithm,
AIDS Research and Human Retroviruses, 1996, Vol. 12, No. 7, pp. 593-610. |
|
| 9.
Anne S. De Groot, Hammett TM, Scheib RG, Barriers to Care of HIV-Infected
inmates: a public health concern, AIDS Reader, 1996, May / June,
pp. 78-87. |
|
| 10.
De Groot AS, Jesdale BM, Szu E, Schafer JR, Chicz RM, Deocampo G. An
interactive Web site providing major histocompatibility ligand predictions:
application to HIV research. AIDS Res Hum Retroviruses. 1997
May 1;13(7):529-31. |
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|
| 11.
Gampper, SNR, George JA, Carter EJ, Jesdale BM, Flanigan TP, Mayer KH, Anne
S. De Groot, Co-infection with M. tuberculosis (Mtb) and HIV in high
risk clinical care settings in Rhode Island, AIDS Care , 1998,
Vol. 10 , No. 2, pp. 221-229. |
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12. Santiago ML, Santiago EG, Hafalla JCR, Manalo, MA, Orantia, L, Cajima,
MNB, Martin C, Cuaresma, C, Dominguez CE, Borromeo ME, Anne S. De Groot
, Flanigan TP, Carpenter CJ, Mayer KH, Ramirez B, Molecular Epidemiology
of HIV-1 Infection in the Phillippines, 1985-1997: Transmission of Subtypes
B and E and Potential Emergence of Subtypes C and F, J. AIDS and
Hu Retrovirology, 1998, Vol. 18, No. 3, pp. 260-269. |
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| 13.
Schafer JA, Jesdale BM, George JA, Kouttab NM, Anne S. De Groot, Prediction
of well-conserved HIV-1 ligands using a Matrix-based Algorithm, EpiMatrix,
Vaccine, 1998, Vol. 16, No. 19, pp. 1880-1884. |
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| 14.
Fink MJ, Goodman, AK, Hight E, Miller- Mack E, Anne S. De Groot, Critical
prevention, critical care: gynecological and obstetrical aspects of comprehensive
HIV prevention and treatment among incarcerated women. J. Correctional
Health Care, 1998, Vol. 5, Issue 2, pp.201-223. |
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| 15.
Anne S. De Groot, Leibel SR, Zierler S, A Standard of HIV care for incarcerated
women: Northeastern United States' Experiences. J. Correctional Health
Care, 1998, Vol. 5, Issue 2, pp. 139-177. |
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| 16.
Anne S. De Groot, Leibel SR, Reports from the New England Regional Symposium
on HIV Infection among incarcerated women. J. Correctional Health
Care, 1998, Vol. 5, Issue 2, pp. 125-127. |
|
| 17.
Xia Jin, DF Nixon, CGP Roberts, Nixon DF, J Safrit, LQ Zhang, YX Huang,
N Bhardwaj, B Jesdale, AS De Groot, RA Koup, Identification of subdominant
cytotoxic T lymphocyte epitopes encoded by autologous HIV type 1 sequences,
using dendritic cell stimulation and computer-driven algorithm. AIDS
Res Hu Retroviruses Vol 16, No.1, pp. 67-76, January 2000. |
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| 18.
Anne S. De Groot, HIV infection among incarcerated women: Epidemic behind
bars. AIDS Reader 2000;10:287-295. |
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19. Anne S. De Groot, Bick, J, Thomas, D, Stubblefield, E, HIV Clinical
Trials in Correctional Settings: Right or Retrogression? AIDS
Reader. 2001;11(1):34-40. |
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| 20.
Bond KB, Sriwanthana B, Hodge TW, De Groot AS, Mastro TD, Young NL, Promadej
N, Altman JD, Limpakarnjanarat K, McNicholl JM. An HLA-directed molecular
and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic
T lymphocyte epitopes in HIV-1 infected Thais. AIDS Research and
Human Retroviruses 2001; 17(8):703-18. |
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| 21.
Anne S. De Groot, H. Sbai, C. Saint-Aubin, W. Martin, A. Bosma, G. Skowron,
K. H. Mayer Designing HIV-1 vaccines to reflect viral diversity and the
global context of HIV/AIDS. AIDScience 1(2) June 22,2001. |
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| 22.
Anne S. De Groot , Andrew Bosma, Natasha Chinai, Julie Frost, Bill M. Jesdale,
Michael A. Gonzalez, William Martin, Caitlin Saint-Aubin.From genome
to vaccine: In silico predictions, ex vivo verification Vaccine
2001 Aug 14;19(31):4385-95. |
|
| 23.
Anne S. De Groot, Saint Aubin, CS, Rayner, J, Martin, W. Rapid Determination
of HLA B*07- ligands from the West Nile Virus genome. Emerging Infectious
Diseases, Vol. 7, No. 4, July-August 2001: 706-713. |
| 24.
H. Sbai, A. Mehta, Anne S. De Groot. Use of T cell epitopes for vaccine
development. Current Drug Targets - Infectious Disorders, 2001, 1, 283-293.
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| |
| Submitted
or in Press |
| Chapter.
Anne S. De Groot, Hakima Sbai, Bill Martin, and Jay A. Berzofsky. Use
of bioinformatics to predict MHC ligands and T-cell epitopes: Application
to vaccine design. Methods in Microbiology: Immunology of Infection,
2nd Edition. (Volume 32 in the Methods in Microbiology series). Edited by
Stefan Kaufmann and Dieter Kabelitz. [In press]. |
|
|
Chapter.
H. Sbai, A. S. De Groot, J. Sidney, A. Sette and Jay A. Berzofsky . High
throughput informatics and in vitro assays for T cell epitope determination:
Application to the design of epitope-driven vaccines. New Generation
Vaccines, 3rd edition, Myron M. Levine, B. Kaper, Rino Rappuoli, Margaret
Liu, Michael Good, ed.s, Marcel Dekker Inc. NYC, NY. [Submitted 030602
to editors].
|
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| Anne
S. De Groot, Hakima Sbai, Caitlin Saint Aubin, Julie McMurry, William Martin.
Immuno-informatics: Mining the genome for Vaccine Components. Immunology
and Cell Biology [Submitted 030103 for June 2002 publication] |
|
| Anne
S. De Groot, Natasha Chinai , Hakima Sbai, Assan Jaye, Andrew Bosma, Hilton
Whittle. Successful identification of novel HIV-2 epitopes and a single
"cross-reactive" HIV-1/HIV-2 CTL epitope using a bioinformatics approach.
In preparation. |
|
| Anne
S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai,
Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, Ken Mayer.
Mapping Cross-clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach.
J. Virology. Revision in preparation. |
|
| Anne
S. De Groot, James Rayner, William Martin. Modeling the immunogenicity
of therapeutic proteins using T cell epitope mapping. Proceedings of
a symposium (IAB). Developments in Biologicals. (submitted March 5, 2002). |
|
|
A. S. De Groot, A. Bosma, C. Saint-Aubin, H. Sbai, W. Martin. Evaluation
of the Nakayama-NIH Japanese encephalitis virus vaccine and the NY99 West
Nile virus genome for cross-reactive T cell epitopes. Emerging Infectious
Diseases (Submitted). |
|
| Dong,
Y, Dimaria, S, Sun, X, Jesdale, BM, Anne S. De Groot, Rom, WN, Bushkin,
Y, HLA-A2-restricted CD8+ cytotoxic T-cell responses to novel Mycobacterium
tuberculosis targets superoxide dismutase and alanine dehydrogenase.
(Submitted). |
|
Other
Publications
(Not Peer Reviewed) |
|
| 1.
Raybourne, RB. Hermann, E, Kellner, H, De Groot, A.S., Huang, F, Willliams,
K.M., Roth, G., Yu, D.T.Y. The role of peptides in the recognition of
HLA-B27 by cytotoxic T cells and by antibodies, with special emphasis on
arthritis patients, Chapter 11 in HLA-B27 in the Development
of Spondyloarthropathies. Carlos Lopez Larrea. R. G. Landes Bioscience,
Austin Texas USA.1997. |
|
| 2.
Flanigan TP, Vigilante K, Burzinsky J, Bubly G, Kim J, Cu-Uvin S, DeCiantis
ML, Normandy L, Snead M, Anne S. De Groot, DeBuono BA, Medical Care of
HIV-Infected Prisoners: The Rhode Island Experience, in AIDS Clinical
Research and Care: Meeting the Challenges of an Epidemic in Flux, PRIM&R
Conference Proceedings Oct 29-30, 1992. |
|
| 3.
Anne S. De Groot, Scheib RG, McGowan K, Schmid CP, Lieberman J, Wyler DJ,
T-cell responses to Mycobacterium tuberculosis antigens in the HIV-infected
host. Vaccines 93, Cold Spring Harbor Press, Cold Spring Harbor,
NY, pp. 251-257. |
|
| 4.
Anne S. De Groot, Jesdale BM, Meister GE, Muni N, Roberts CGP, Prediction
of T Cell Epitopes for HIV vaccine development by computer-driven algorithm,
in HIV Molecular Immunology Database 1995, Bette Korber, Gerald Meyers
eds., Los Alamos National Laboratories, New Mexico, pp. iv17 - iv28. |
|
| 5.
Flanigan TP, Bury-Maynard D, Vigilante K, Burzinsky J, Bubly G, Kim J, Rich
JD, Zierler S, DeCiantis DL, Normandy L, Snead M, Anne S. De Groot, Loberti
P, DeBuono BA, The Rhode Island Prison Release Program, in Progress
and Challenges in Linking Incarcerated Individuals with HIV/AIDS to Community
Services, Health Resources and Services Administration Bureau of Health
Resources Development Office of Science and Epidemiology, June 1995. |
| |
| 6.
Anne S. De Groot, Meister GE, Roberts CGP, Edelson BT, Ramirez B, Berzofsky
JA, Algorithms for Mycobacterial Vaccine Development, Proceedings
of the International symposium on Bovine TB in Animals and Human Beings,
USDA/NIAID, NIH, 1995. |
|
| 7.
Anne S. De Groot, Carter EJ, Roberts CGP, Edelson BT, Jesdale BM, Meister
GE, Houghten RA, Montoya J, Romulo RC, Berzofsky JA, and Ramirez BDLL, A
novel algorithm for the efficient identification of T cell epitopes: prediction
and testing of candidate TB vaccine peptides in genetically diverse populations
, Vaccines 96, Cold Spring Harbor Laboratory, Cold Spring Harbor,
NY, pp. 127-134. |
| |
| 8.
Anne S. De Groot, Meister GE, Cornette JL, Margalit H, DeLisi C, and Berzofsky
JA; Computer Prediction of T Cell Epitopes, in New Generation
Vaccines, 2nd edition, Myron M. Levine, Graeme C. Woodrow, James B.
Kaper, Gary S. Cobon, eds., Marcel Dekker Inc. NYC, NY, 1996. |
| |
| 9.
Jesdale BM, Deocampo G, Meisell J, Mullen L, Beall J, Marinello M, Anne
S. De Groot, Matrix-based prediction of MHC-binding peptides: the Epimatrix
algorithm, reagent for HIV research,Vaccines 97, pp. 57-64, Cold
Spring Harbor Laboratory Press 1997. |
|
|
10. Anne S. De Groot and Debi Cuccinelli, Put her in a cage: Childhood
sexual abuse, incarceration, and HIV infection, chapter in The Gender
Politics of HIV in Women: Perspectives on the Pandemic in the United States
J. Manlowe and N. Goldstein, ed., New York University Press, 1997. |
|
| 11.
Nguyen, KB, Suri, PK, Shah, AM, Goldberg, M, De Groot, AS, and Knopf, PM.
Differential immune responses against a Schistosoma mansoni candidate
vaccine antigen in three murine strains. Vaccines 97, 213-217. |
| |
| 12.
Anne S. De Groot, Jesdale BM, Berzofsky JA, Prediction and determination
of MHC ligands and T Cell Epitopes, Chapter 3, Immunology Methods,
SHE Kaufmann, ed, Methods in Microbiology, Vol 25, p 79-106, Academic Press,
NY 1998. |
| |
| 13.
Anne S. De Groot, Leibel SR, The need for Compassionate Care: HIV Infection
Among Incarcerated Women, Medicine and Health, RI, Vol 81. No.
6, p 209-211, 1998. |
| |
| 14.
Anne S. De Groot, Stevens J, Pratt L, Leibel SR, Zierler S, Setting the
Standard for Care: HIV Risk Exposures and Clinical Manifestations of HIV
in Incarcerated Massachusetts Women, New England Journal of Criminal
and Civil Confinement, Vol 24, pp 353-378, July 1998. |
| |
| 15.
Anne S. De Groot and Rothman FG, In Silico Predictions; in Vivo Veritas
(News and Views), Nature Biotechnology Vol 17, No. 6, pp. 533-34,
June 1999. |
|
| 16.
De Groot AS. Shedding light on correctional HIV care (editorial).
AIDS Reader 2000;10:285-286. |
|
| 17.
Anne S. De Groot , Jackson, EH, Stubblefield, S. Clinical Trials in Correctional
Settings: Proceedings of a conference held in Providence, RI, Oct 14-15
1999. Rhode Island Journal of Medicine, 83; (12) December, 2000,
pp 376-379. |
|
| 18.
Anne S. De Groot, Women Prisoners with HIV: An Open Letter from a Prison
Doctor (1996). In Correctional Perspectives: Views from Academics, Practitioners,
and Prisoners edited by Paul Cromwell and Leanne Fiftal Alarid, Roxbury
Publishing Company. 2001. |
|
| Other
Publications (Newsletter and magazine articles) |
| 1.
A.S. De Groot, Update from the 6th Conference on Retroviruses and Opportunistic
Infections Chicago, Illinois, Jan 31-Feb 3 1999. HEPP News, April
1999 , 1 (4) pp. 1-4. |
|
|
2. A.S. De Groot, Update from the 6th Conference on Retroviruses and
Opportunistic Infections Chicago, Illinois, Jan 31-Feb 3 1999 (Part
Two). HEPP News, May 1999, 1 (5) pp.1-5. |
|
| 3.
A.S. De Groot, K. Anastos, S.R. Leibel, E. Stubblefield, Women in Prison:
The Impact of HIV. HEPP News, June 1999 1 (6) pp.1-7. |
| |
| 4.
A.S. De Groot, J. Bick, F. L. Altice, HIV Management Guidelines: News
and Trends. HEPP News, February 2000, 2 (2) pp.1-3. |
| |
|
5. A.S. De Groot, HIV Infection among Incarcerated Women: an Epidemic
behind the Walls. HEPP News, April 2000; 3(4) pp.1-4. |
| |
|
6. A.S. De Groot, Joseph Bick. The Correctional Doctor's Dilemma: Hepatitis
C Treatment. HEPP News, June 2000, 3 (6) pp. 1-5. |
| |
| 7.
A. S. De Groot, Corrections on the National Conference Agenda: Update
from the 24th NCCHC, HEPP News, October 2000, 3 (9) pp. 1-5. |
| |
|
8. A. S. De Groot, Treatment Update for Correctional HIV providers: News
from Chicago HEPP News, February 2001, 1 (2) pp. 1-5. |
| |
9.
A. S. De Groot, E. Stubblefield, The new HAART: What it means for Prisoners.
Medscape Infectious Diseases (Prison Series).
http://www.medscape.com/medscape/ID/journal/2001/v03.n02/mid0306.degr/mid0306.degr.html.
(Posted March 2001). |
| |
|
10. A.S. De Groot, HCV: The Correctional Conundrum. HEPP News,
April 2001, 4 (4) pp. 1-5. |
| |
11.
Anne S. De Groot, MD, Elizabeth Stubblefield, Joe Bick, Infections Behind
Bars: Hepatitis C: A Correctional-Public Health Opportunity. Medscape Infectious
Diseases (Prison Series). http://www.medscape.com/medscape/ID/journal/2001/v03.n03/mid0614.groo/mid0614.groo-01.html
(Posted June 2001) |
|
12.
Marthali Nicodemus, Hakima Sbai, and Anne S. De Groot. Urgency and optimism
at the AIDS Vaccine 2001 conference. AIDScience Vol. 1, No. 11,
October 2001. http://www.aidscience.com/Articles/aidscience009.asp
(Posted October 2001). |
| |
|
13. Anne S. De Groot, MD, Immunotherapy of HIV: On the Horizon? HEPP
News October 2001, 4 (11) pp. 1-5. |
|
| 14.
De Groot AS. Women incest survivors in prison. An open letter from a
prison doctor to those who care for women living with HIV. Positively
Aware. 2001 Jul-Aug;12(4):27-9. |
|
| 15.
De Groot AS. Alarming statistics about incarcerated women. Positively
Aware. 2001 Jul-Aug;12(4):19-21. |
|
| 16.
De Groot, AS and Thomas, D. Thomas. Preparing for Bioterrorist Threats
in Corrections. HEPP News February 2002 Vol. 5, Issue 2. |
|
| Abstracts/poster
presentations |
| 1.
Anne S. De Groot, Clerici M, Hosmalin A., Barnd D, Hughes S, Hendrix JA,
Houghten R, Shearer GM, Berzofsky JA, Identification of a T-Helper cell
epitope in HIV reverse transcriptase which is also recognized by CTL,
poster and abstract, New Approaches to Vaccines, Cold Spring Harbor Laboratory
September, 1991. |
|
| 2.
Gozansky W, Anne S. De Groot, Noble J, Scheib RJ, Griffiths JK, Wong JB,
Prophylactic therapy for Toxoplasma Infection in HIV-1 Seropositive Subjects:
Decision Analysis, poster and abstract, IX International conference on AIDS,
Berlin, 1993. |
|
| 3.
Gozansky W, Schmid CP, Moody S, Cheeseman S, McGowan K, Anne S. De Groot,
A Prospective Study of the Incidence of Reactivation of Latent Toxoplasma
Infection in HIV-1-Seropositive Subjects in Massachusetts, poster and
abstract, IX International Conference on AIDS, Berlin, June 1993. |
|
|
4. Anne S. De Groot, Woo D, Meister GE, Berzofsky JA, Identification
of antigenic regions of Mycobacterium tuberculosis proteins using Natural
Peptide and Amphi algorithms, poster and abstract, Conference on MultiDrug
Resistant TB, Bethesda, MD September, 1993. |
|
| 5.
Anne S. De Groot, Shinde SR, Roberts CGP, Haskal R, Meister GE ,Lieberman
J, A comparison of Cell-mediated responses to Mycobacterium tuberculosis
(Mtb) antigens in Mtb-immune subjects and HIV-seronegative and HIV-seropositive
Mtb-susceptible subjects, poster and abstract, New Approaches to Vaccines
including AIDS, Cold Spring Harbor Laboratory September, 1993. |
|
| 6.
Anne S. De Groot, Meister GE, Roberts CGP, Edelson BT, De Groot LJ, Berzofsky
JA, Two novel algorithms for the identification of T cell epitopes that
are based on MHC binding motifs poster and abstract, Molecular Approaches
to the Control of Infectious Diseases, Cold Spring Harbor Laboratory, October
1994. |
|
| 7.
Meister GE, Roberts CPG, Berzofsky JA, Anne S. De Groot. Mycobacterium
tuberculosis peptide epitopes predicted by two novel epitope
identification algorithms presentation and abstract, Molecular Approaches
to the Control of Infectious Diseases, Cold Spring Harbor Laboratory, Long
Island, New York, October 1994. |
|
| 8.
Roberts CGP, Meister GE, Berzofsky JA, Anne S. De Groot, Peptide epitopes
for five HIV-1 proteins predicted by a novel T cell epitope prediction algorithm,
poster and abstract, NCDVG conference, Washington DC, October 1994. |
|
|
9. Anne S. De Groot, Meister GE, Roberts CGP, Edelson BT, De Groot LJ, Berzofsky
JA, Two novel algorithms for the identification of T cell epitopes that
are based on MHC binding motifs, poster and abstract, Molecular Approaches
to the Control of Infectious Diseases Cold Spring Harbor Laboratory, October
1994. |
|
|
10. Meister GE, Roberts CGP, Berzofsky JA, Anne S. De Groot. Mycobacterium
tuberculosis peptide epitopes predicted by two novel epitope
identification algorithms, poster and abstract, Molecular Approaches
to the Control of Infectious Diseases, Cold Spring Harbor Laboratory, Long
Island, New York, October 1994. |
|
| 11.
Stevens J, Zierler S, Cram V, Dean D, Mayer KH, Anne S. De Groot, The
Prevalence of HIV, Risks for HIV Infection, and Gynecological Comorbidity
in Women Incarcerated in Massachusetts, poster and abstract, Conference
on Women's Health, Washington DC, June 1994. |
|
| 12.
Anne S. De Groot, Kimberly Fisher, Caroline G.P. Roberts, Gabriel E. Meister,
Brian T. Edelson, Katherine McGowan, John Phair, Ken Mayer, T cell response
to Tuberculosis in HIV seropositive subjects; longitudinal and cross-sectional
analysis, poster and abstract, Keystone Symposium on the Molecular Mechanisms
of Tuberculosis, February 1995. J. Biol. Chem., suppl 19B: abstract B3 402,
1995. |
|
| 13.
Anne S. De Groot, Fisher K, Roberts CGP, Meister GE, Edelson BT, McGowan
K, Phair J, Mayer K, T cell response to Tuberculosis in HIV seropositive
subjects; longitudinal and cross-sectional analysis, Poster and abstract,
Keystone Symposium on the Molecular Mechanisms of Tuberculosis, February
1995. J. Biol. Chem., 1995, suppl 19B: abstract B3 402. |
|
| 14.
Anne S. De Groot, Stevens J, Cram V, Chalfen B, Mayer K, Zierler K, Childhood
sexual abuse increases vulnerability to HIV exposure among incarcerated
women,1st National Congress on HIV in Women, poster and abstract, Washington
DC February 1995. |
|
|
15. Anne S. De Groot, Stevens J, Chalfen B, Cram V, Dean D, Mayer K, Zierler
S, HIV and gynecological comorbidity among women incarcerated in Massachusetts,
poster and abstract,1st National Congress on HIV in Women, Washington DC,
February 1995 |
|
| 16.
Pratt L, Stevens J, Andujar E, Manlowe J, Flanigan T, Zierler S, Anne S.
De Groot; Discharge planning needs of incarcerated women living with
HIV, poster and abstract ,1st National Congress on HIV in Women, Washington
DC February 1995. |
|
|
17. Gampper, SNR, Nacar E, O'Connell J, Stein M, Fisher AE , Jesdale W,
Carter J, Mayer K, Anne S. De Groot, Co-infection with M. tuberculosis
and HIV-1 in Providence, poster and abstract, American Thoracic Society
Meeting, Seattle WA, May 1995. |
|
| 18.
Renaud T, Carter J, Jesdale BM, Anne S. De Groot, Reducing the risk of
tuberculosis transmission in the prison setting through the use of environmental
controls including UVG Irradiation and HEPA filtration, poster and abstract,
Lancet Tuberculosis Conference, Sept 14-15, 1995, Washington DC. |
|
| 19.
Anne S. De Groot, Wong S, O'Connell J, Nacar L, Meister GE, Jesdale BM,
Carter J , Use of pediatric tuberculosis infection as a marker of tuberculosis
transmission in communities in Providence, Rhode Island, poster and
abstract, Lancet Tuberculosis Conference, Sept 14-15, 1995, Washington DC.. |
|
| 20.
Anne S. DeGroot, Stevens J, Dean D, Cram V, Andujar E, George JA , Goodman
AK, Poutsiaka DD, Scheib RG, Cohen JL, Health services for HIV seropositive
incarcerated women: The Framingham model, poster and oral presentation
at the National Commission on Correctional Health Care 19th conference,
November 12-13, 1995. |
|
| 21.
Renaud R, Carter J, Jesdale BM, Anne S. De Groot, Reducing the risk of
tuberculosis transmission in the prison setting through the use of environmental
controls: A cost benefit analysis, poster and oral presentation at the
National Commission on Correctional Health Care 19th conference, November
12-13, 1995. |
| |
| 22.
Nguyen KB, George JA, Dong KL, Corah T, Whittle H, Jesdale BM, Anne S. De
Groot, Designing a subunit vaccine for M. tuberculosis using a novel
epitope prediction algorithm: Gambian responses to population weighted vs
unweighted peptides, poster and abstract, Molecular Approaches to the
Control of Infectious Diseases Cold Spring Harbor Laboratory, September
1996 |
|
| 23.
Anne S. DeGroot, Zierler, S,Stevens, J,Dean, D, Ferdinand MM,Jesdale, BM,
George, JA, Scheib RG,.HIV risk behaviors and HIV related morbitidy in
a cohort of incarcerated women in Massachusetts, poster and abstract,
International AIDS Conference, Vancouver, 1996. |
|
| 24.
Schafer JR, Gotch F, Mayer K, Ho D, Koup R, Anne S. De Groot. The predicted
utility of several phase III HIV-1 vaccines for selected world populations,
poster and abstract, Molecular Approaches to the Control of Infectious Diseases
Cold Spring Harbor Laboratory, September 1996. |
|
| 25.Santiago
MLO, Hafalla JCR, Jesdale BM, Ramirez BDLL, Anne S. De Groot, Identification
of Phylogenetically conserved clusters of published and predicted HIV 1
CD8+ CTL epitopes in geographically diverse populations, poster and
abstract, presentation #98.009. International Infectious Disease society
meeting, Hong Kong, June 1996. |
|
| 26.
Natividad M, Cajimat B, Santiago MLO, Hafalla JCR, Libranda-Ramirez BDL,
Jesdale BM, Anne S. De Groot, Clusters of published HIV-1 CD8+ CTL epitopes:
peptide diversity and HLA-dependent population coverage, poster and
abstract, Annual Convention of the Philippine Society for Biochemistry and
Molecular Biology, December 1996. |
|
| 27.
Jesdale BM, Schafer JR, Santiago MLO, Granek JA, Roberts CGP, Koup RA, Anne
S. DeGroot Population-dependent prediction of CTL epitopes for HIV clades
using a computer-driven algorithm, poster and abstract, International
AIDS conference, Vancouver, July 1996. |
|
| 28.
Jin X, Nixon DF, Roberts CGP, Safrit J, Zhang LQ, Huang YX, Jesdale BM,
Anne S. DeGroot, Koup RA, Prediction and validation of HLA-B7 restricted
CTL epitopes based on upon autologous HIV-1 sequences, poster and abstract,
Keystone HIV/AIDS Pathogenesis meeting, Keystone, Colorado,1997. |
|
| 29.
Bond K, Pau CP, Malegam JY, Anne S. DeGroot, Szu E, Hodge TW, Mastro TD,
Stephens H, McNicholl JM, HLA-A11 Cytotoxic T Lymphocyte Epitopes in
HIV-1 env Subtype E, poster and abstract, Keystone HIV/AIDS Pathogenesis
meeting, 1997. |
|
| 30.
Anne S. De Groot, Jesdale BM, Szu E, Mullen L, Deocampo D,.Matrix-based
definition of MHC ligands from primary HIV-1 and HIV-2 protein sequences:
the EpiMatrix/HIV Web Site, poster and abstract, Keystone HIV/AIDS Pathogenesis
meeting, 1997. |
|
| 31.
Barnea JD, Bollinger RC, George JA, Jesdale BM, Anne S. De Groot, Towards
Developing an HIV-1 Vaccine for India: Computer-Driven Prediction and Analysis
of Cytotoxic T-Lymphocyte (CTL) Epitopes, poster and abstract, First
Annual Vaccine meeting (ASM, NIAID), Washington DC 1998. |
|
|
32. Brichkov I, George JA, Whalen RJ, Anne S. DeGroot, Construction of
a DNA vaccine for TB containing promiscuous T cell epitopes, poster
and abstract, First Annual Vaccine meeting (ASM, NIAID, NFID), Washington
DC 1998. |
|
|
33. Bond KB, Pau CP, Malegam JY, Anne S. DeGroot, Jesdale, BM, Hodge TW,
Mastro TD, McNicholl SH, HLA-A11 Cytotoxic T Lymphocyte Epitopes in HIV-1
env Subtype E, poster and oral presentation at the International AIDS
Conference, Geneva, June1998. |
|
| 34.
Anne S. De Groot, Jesdale BM, Fleischmann RD, Matrix based prediction
of MHC binding peptides: the TIGR/EpiMatrix website, reagent for TB research,
poster and abstract, Conference on TB: Molecular mechanisms and Immunopathogenesis,
Keystone, Colorado, April 1998. |
|
|
35. Anne S. De Groot, Schafer JR, Barnea JD, George JA, Jesdale BM, Evaluation
of HIV sequences for MHC binding patterns by computer driven algorithm,
poster and abstract, HIV Evolution Meeting, Santa Fe, NM, April 1998. |
|
| 36.
Anne S. DeGroot , George JA, Gonzalez M, Chinai N, Genome to T Cell:
Epitope-Driven Vaccine Design, Abstract and oral presentation, Microbial
Genomes Conference, Chantilly, VA, January 1999. |
|
| 37.
Anne S. DeGroot, George J, Gonalez M, Jin X, Bond K, Koup R, McNicholl J,
Prospective Identification of MHC Ligands and CTL Epitopes from HIV Proteins
using Bioinformatics, Abstract number 43, Poster and oral presentation
at the 6th conference on Retroviruses and Opportunistic Infections, Chicago,
IL, January 1999. |
|
| 38.
Anne S. De Groot, Gonzalez M, Chinai N, Barnea JD, From Genome to T Cell:
Searching for Agretopes, poster and abstract, Second Annual Vaccine
meeting (ASM, NIAID, NFID), Washington DC 1999. |
|
| 39.
Anthony Breu, Michael Gonzalez , Igor Brichkov, Robert Whalen, Hakima Sbai,
Anne S. De Groot. Use of the plasmid pRc/CMV-HBs(S) as a vector for an
epitope-based DNA vaccine against Mycobacterium tuberculosis. Molecular
Approaches to Vaccines Meeting, Cold Spring Harbor Laboratory, Dec 6-8,
1999. Poster presentation. |
|
| 40.
Natasha Chinai , Assan Jaye, Andrew Bosma, Hilton Whittle, Anne S. De Groot.
Successful identification of novel HIV-2 epitopes and a single "cross-reactive"
HIV-1/HIV-2 CTL epitope using a bioinformatics approach. Molecular Approaches
to Vaccines Meeting, Cold Spring Harbor Laboratory, Dec 6-8, 1999. Poster
presentation. |
|
| 41.
Michael Gonzalez, Julie Frost, Andrew Bosma, James Robert Schafer, Robert
Whalen, Hakima Sbai Gail Skowron, Anne S. De Groot. Developing a "World
Clade" HIV Vaccine using a Bioinformatics Approach. Molecular Approaches
to Vaccines Meeting, Cold Spring Harbor Laboratory, Dec 6-8, 1999. Oral
and Poster presentation. |
|
| 42.
A. S. De Groot, M. Gonzalez, J. Frost, A. Bosma, J. R. Schafer, G. Skowron,
W. Martin. Designing and Assessing HIV Vaccines for Cross-Clade Immunogenicity
using Bio-informatics Abstract number 589, Poster at the 6th conference
on Retroviruses and Opportunistic Infections, Chicago, IL, January 1999. |
|
|
43. Natasha M. Chinai, Michael B. Gonzalez, Andrew Bosma, Judith A. George,
Robert C. Bollinger, Anne S. DeGroot. Towards developing an HIV 1 vaccine
for India: Computer driven prediction and analysis of CTL epitopes.
Molecular approaches to Vaccine Design. Cold Spring Harbor Laboratory, Cold
Spring Harbor New York. Dec 1999. |
|
44.
Anthony Breu, Michael Gonzalez , Igor Brichkov, Judy George, Robert Whalen,
Hakima Sbai , Anne S. De Groot. Use of the plasmid prc/CMV-HBS(S) as
a vector for an epitope-based vaccine against Mycobacterium
tuberculosis. Molecular approaches to Vaccine Design. Cold Spring Harbor
Laboratory, Cold Spring Harbor New York. Dec 1999. |
|
45.
A. De GROOT, J.GEORGE, M.GONZALEZ, X.JIN, K.BOND, R.KOUP, J.McNICHOLL
Prospective Identification of MHC Ligands and CTL Epitopes from HIV Proteins
using Bioinformatics 7h Conference on Retroviruses and Opportunistic
infections, San Francisco, Jan 2000, Poster. |
|
| 46.
S. Demaria, X Sun, BM Jesdale, AS De Groot, C Steinzig, WN Rom, and Y Bushkin,
HLA A2 Restricted, CD8 Dependent Ctyotoxic T cell resposne to mycobacterial
superoxide dismutase. Microbial Pathogenesis and Host Response, Cold
Spring Harbor, NY, 2000. |
|
| 47.
A. De Groot, J. McMurry, H. Sbai, and W.Martin. From Genome to T Cell:
Epitope-Driven TB Vaccine Design. Molecular and Cellular Aspects of
Tuberculosis Research in the Post-Genome Era. (Keystone Symposia) January
25-30, 2001 (Abstract 262) |
|
| 48.
A. De Groot, J. Frost1, M. Gonzalez, C. Saint-Aubin, H. Sbai, G. Skowron,and
W. Martin. "World Clade" Vaccine Design: Selection and Confirmation of
Conserved HIV-1 CTL Epitopes Using a Bioinformatics Approach. 8th Conference
on Retroviruses and Opportunistic infections, Chicago, Feb 2-5 2001, Poster
195 |
|
| 49.
P. Hansasuta, S. Buranapraditkul, J. Sanruk, T. Rostron, P. Phanuphak, K.
Ruxrungtham, J. McNicholl, Kyle Bond, Anne De Groot, and S. Rowland-Jones.
Cross-Clade CTL in Thai HIV-Infected Subjects. 8th Conference on
Retroviruses and Opportunistic infections, Chicago, Feb 2-5 2001, Poster
164 |
|
|
50. Neel K. Shah, Michael J.B. Gonzalez, Andrew Bosma, Kenneth H. Mayer,
Anne S. De Groot. Cross-Clade Conservation of HIV-1 CTL Epitopes in the
Aidsvax® and Aventis CP205™ Vaccines. NFID Fourth Annual Conference
on Vaccines, Arlington VA 2001. Oral presentation S17. |
|
| 51.
Anne S. De Groot, Caitlin Saint-Aubin, James Rayner, William Martin Rapid
Determination of candidate HLA B*07- restricted CTL epitopes from the West
Nile Virus NY99 genome. NFID Fourth Annual Conference on Vaccines, Arlington
VA 2001. Oral presentation Poster presentation P17. |
|
| 52.
Natasha Chinai, Assan Jaye, Andrew Bosma, Hilton Whittle, Anne S. De Groot.
Defining novel immunogenic HIV-2 peptides using a bioinformatics approach.
Keystone meeting HIV Vaccines. April 2001. |
|
| 53.
Hakima Sbai, Julie McMurry, Bill Martin, James Rayner, Julie Frost, Anne
DeGroot. Computational methods for mapping T cell epitopes: A streamlined
approach to vaccine design. FOCIS Annual Meeting, Boston, May 4-7. |
|
| 54.
Hakima Sbai, Natasha Chinai, Julie Frost, Andrew Bosma, Gail Skowron, William
Martin, Anne De Groot. Designing an HIV world clade vaccine using bioinformatics-based
approach, Second International Conference on Vaccine Development and
Immunotherapy in HIV, San Juan, May 22-25 2001. |
|
| 55.
Hakima Sbai, Julie Frost, Caitlin-Saint-Aubin, Julie McMurry, Andrew Girvin,
Bill Martin, Andrew Bosma, James Rayner, Anne DeGroot. Computational
methods for mapping T cell epitopes in the TB proteome: A streamlined approach
to vaccine design. U.S.-Japan Joint Tuberculosis/Leprosy Conference,
New Orleans, July 15-17 2001. |
|
|
Invited Presentations |
- Infectious
Diseases, Immunopathogenesis, Vaccines
|
Tuberculosis:
Epidemiology and Treatment in the 1990's, Pulmonary Rounds, St.
John's Hospital, Lowell MA, December 13, 1991.
|
T Cell Responses to Mycobacterium tuberculosis in the HIV-infected
Host , Modern Approaches to New Vaccines, Cold Spring Harbor Laboratory,
Sept 20, 1992.
|
Tuberculosis:
Multi Drug Resistant Tuberculosis and Drug Therapy, Pulmonary Rounds,
St. John's Hospital, Lowell MA, December 10, 1992.
|
Multi Drug Resistant Tuberculosis, Massachusetts Association
of Physician's Assistants Annual Meeting, Falmouth, MA , October 1992.
|
Immunopathogenesis of an Epidemic: TB and HIV infection,
Invited Speaker. Grand Rounds, Lemuel Shattuck Hospital, Boston MA, January
19, 1993
|
Two Novel Computer Driven T Cell Epitope Prediction Algorithms for
Vaccine Development Invited Speaker. Brown University Immunology
Seminar, Brown University, Providence, RI, September 22, 1994.
|
Algorithms
for mycobacterial vaccine development, Invited Speaker. International
symposium on Bovine TB in Animals and Human Beings, USDA/NIAID, NIH,
May 1995.
|
A novel
algorithm for the efficient identification of T cell epitopes: prediction
and testing of candidate TB vaccine peptides in genetically diverse
populations, Invited Speaker. Cold Spring Harbor meeting on Vaccines
for Infectious Diseases, September 1995.
|
Computer
Algorithms for Vaccine Development, Invited Speaker. Biology and
Technology Seminar: Boston University (Dr. Charles Delisi, host), Boston
MA, September 1995.
|
Computer
Algorithms for TB Vaccine Development, Invited Speaker. Public Health
Research Institute (Dr. Marilla Gennaro, host), New York, October 2,
1995.
|
Evolution
of HIV Quasi Species: Response to Immune Pressure? Invited Speaker.
Aaron Diamond AIDS Research Center (Dr. Rick Koup, host), New York City,
NY November 20,1995.
|
EpiMatrix
algorithm, reagent for HIV vaccine research, Invited Speaker. Molecular
Approaches to Vaccines for Infectious Diseases, Cold Spring Harbor Laboratory,
New York September 1996.
|
Comstock
Conference on Epidemiology and Control of TB: Vaccines & TB Control,
Invited Participant, Baltimore Maryland; organized by Phil Hopewell,
UCSF: June 12, 1996.
|
Matrix
based prediction of MHC binding peptides, Division of AIDS Spring
workshop on HIV Variability and Cellular Immune Recognition, Bethesda,
Maryland, April 29, 1996.
|
Epitope prediction for HIV vaccine development, Harvard AIDS Institute,
HIV Vaccines for Developing Countries: Antigen Design, Boston, Massachusetts,
April 11-18,1996.
|
CTL
workshop: Computer driven epitope prediction for HIV vaccine development,
NCDVG conference on HIV Vaccine development, Invited Speaker. CTL workshop.
(Jim Bradac, DAIDS Program Officer). Bethesda, Maryland, February 29,1996.
|
Computer
Algorithms for CancerVaccine Development, Invited Speaker. Wistar
Institute (Dorothee Herlyn, host), Philadelphia, Pennsylvania, January
1996.
|
Computer
Algorithms for TB and HIVVaccine Development, Invited Speaker. Department
of Immunology (Dr. David McMurray, host), Texas A & M University, College
Station Texas, January 22, 1996.
|
Computer
Algorithms for HIV Vaccine Development, Invited Speaker. HIV Research
Unit, (Dr.s Brigitte Autran, Anne Hosmalin, hosts) Hopital Pitié Salpetrier,
Paris, France, June 12, 1996.
|
Computer
algorithms for TB vaccine design, Invited Speaker. Pasteur Institute
(Dr. Brigitte Gicquel, host) , Paris, France Sept 29, 1997.
|
Computer-driven
Design of new HLA-based vaccines for HIV, Invited Speaker. Partners
AIDS Research Center (Dr. Bruce Walker, host), Massachusetts General Hospital,
February 27, 1997.
|
Symposium
on Immunogenicity of Recombinant Human Proteins. EpiMatrix: Prediction
of MHC ligands, Invited Speaker. Genentech (Dr. Gene Koren, host),
South San Francisco, March 1997.
|
Epitope Predictions for TB vaccine development, Invited
Speaker. Global Tuberculosis Programme for Vaccines and Immunization/Vaccine
Research and Development conference," Definition of Strategies for an
optimal use of Information resulting from Mycobacterial genome sequencing"
at the World Health Organization Headquarters (Dr. John Foulds, organizer),
Geneva September 5-6 1997.
|
TB and
HIV vaccine development, Invited Speaker. Infectious Disease Conference
(Dr. Jennifer Daly, Host) TB/HIV vaccine development, Worcester MA,
March 4, 1998.
|
From Genome to T Cell: Searching for Agretopes, Invited
Speaker. Microbial Genomes conference, sponsored by the Institute for
Genomic Research (TIGR) (Dr. Clare Fraser, host), Chantilly VA, January
30, 1999.
|
HIV Vaccine Development (speaker on panel, presenting
poster, Dr. Doug Nixon, panel chair) 6th conference on Retroviruses and
Opportunistic Infections, Chicago, Illinois, Monday February 2, 1999.
|
Epitope Predictions and Vaccine Testing, Invited Speaker.
EEC committee on the Ethical and Legal Applications of Vaccines (ELAV,
(Robert Whalen, host), Paris, France. January 16-17, 1999.
|
Bio informatics approaches to Vaccine Development for TB
and HIV. Invited Speaker. DASTLR , Center for Disease Control and
Prevention, Immunology, (Dr. Janet McNicholl, host), Atlanta Georgia,
February 11, 1999.
|
Bio informatics approaches to Vaccine Development for HIV,
Invited Speaker. Emory Center for Vaccine Research, (for the CFAR program,
Dr. Mark Feinberg, host), Atlanta, Georgia, February 12, 1999.
|
Scientific Working Group on TB, Participant. World Health
Organization. (Dr. Paul Nunn, organizer), 9-11 February 2000 Geneva, Switzerland
|
From Genome to T cell: In silico predictions, in vivo
veritas. Invited speaker. Symposium on Genomics and Vaccinology.
National Foundation for Infectious Diseases annual Vaccine conference.
April 30-May 2, 2000. (Regina Rabinovich, M.D.)
|
Informatics
Approaches to Vaccine Design. Invited Speaker. Vaccines and Immunotherapeutics
in the Third Millenium CSIRO, Lorne Australia, March 19-21 2000
|
From
Genome to Vaccine: Bioinformatics and Vaccine Design. Invited speaker,
Emerging Technologies Seminar, Center for Biomedical Inventions and Department
of Internal Medicine & Cardiology University of Texas-Southwestern Medical
Center at Dallas, Oct 17, 2000. (Dr. Irene Rombel and Stephen Johnston).
|
Genomic
Approaches for Identifying Vaccine Candidates - Bioinformatics and Predictive
Algorithms. Invited Speaker. Special meeting on Otitis Media: New
Approaches for Analysis, Treatment and Prevention, November 29 and 30,
2000 (Dr. Thomas M. Johnson, NIDCD and Dr. Lauren Bakeletz)
|
Scanning
the TB Genome for DNA Vaccine Epitopes. Invited Speaker. Sequella
TB Vaccine Conference, Nov 3-5, 2000, at Brown University (Carol Nacy,
Director, SGTBF)
|
TB
pathogenesis, Vaccination, and Treatment update. Invited Speaker.
Anesthesiology Rounds, Kent Hospital November 15, 2000 (Steve St. Aubin,
Nurse Anesthetist).
|
Genomics
and Vaccinomics. Invited Speaker. (Dr. Brad Goodner). University of
Richmond, VA, December 11th 2000.
|
Cross-Clade
Conservation of HIV-1 CTL Epitopes in the Aidsvax® and Aventis CP205™
Vaccines National Foundation for Infectious Diseases annual Vaccine
conference. April 30-May 2, 2001.
|
Epitope-Driven
Vaccines for TB and HIV infection, Invited Speaker. (Dr. Kay McGowan)
Grand Rounds, Lemuel Shattuck Hospital, Boston MA, July, 2001
|
Epitope-Driven
HIV Vaccine Development. Invited Speaker (Jim Bradac, Senior Program
Officer). Division of AIDS. June 13, 2001.
|
From
Genome to T cell: Bioinformatics and Vaccine Design. Invited Speaker
(Dr. Marcelo Sztein). June 18,2001. Lecture at Center for Vaccine Development.
( Myron M. Levine, M.D., D.T.P.H. Director). University of Maryland School
of Medicine
|
Computational
Algorithms to Predict T cell Immunogenicity , Conference on Immunogeniciy
of Therapeutic Biological Products, Lister Hill Auditorium, NIH, Bethesda
MD October 31-Nov 2, 2001
|
From
TB Genome to TB Vaccine. Sequella TB 2001 Vaccine Conference, Montreal,
Canada. Renaissance Conference Center, Nov 8th, 2001
|
Developing
an Epitope-Driven Cross-Clade HIV Vaccine using Bioinformatics (Dr.
Ray Dolan) Harvard HIV Vaccine Trial Unit, Harvard Medical School, Nov
16, 2001
|
Plenary
Speaker: From Genome to T Cell: Epitope-Driven Vaccine Design Australian
Society for Immunology Canberra Australia, Dec 1, 2001.
|
| |
Invited
Presentations (Epidemiology/HIV/Women/Prison)
|
- Epidemiology/HIV/Women/Prison
|
Condoms
and HIV Transmission, Member of Panel, Falmouth, Massachusetts Public
School Board Panel July, 1992.
|
Battering and the Cycle of Violence; speaker on the panel "Locked
up and Locked out; Women in Prison," Criminal Justice Institute conference,
Harvard Law School. December 4, 1993.
|
Sexual
Abuse and HIV Risk Taking among Incarcerated Women HIV infection in Women,
1st National Meeting in Washington DC, February 1995; Women's Health Conference,
Women & Infants Hospital, September 30, 1994, Providence RI.
|
HIV
in Incarcerated Women: HIV Update, and Rhode Island Hospital Nursing
Update, March 31, 1994, and New England HIV in Prisons Conference, Wesleyan
College, May 21, 1994.
|
Sexual
Abuse and HIV Risk Taking among Incarcerated Women, Invited Speaker.
Women's Health Conference, Women & Infants Hospital, Providence RI, September
30, 1994.
|
HIV
in Prisons: Breakout group leader at the conference HIV Update: Current
State of the Art, Brown University AIDS program conference, Butler Hospital,
Providence, Rhode Island , January 8, 1994.
|
Risks
for HIV infection among Incarcerated Women, Invited Speaker. Yale
AIDS Colloquium Series (YACS, Dr. Rick Altice, host) New Haven CT , October
12,1995.
|
TB
in Prisons workshop leader, Invited Speaker. New England HIV in Prisons
Conference (and conference co-organizer)Springfield MA, October 20,1995.
|
HIV
infection in Incarcerated Women: Priorities for Research, Invited
Speaker. Clinical AIDS Research; PRIM&R, Boston MA, November 9,10, 1995.
|
The Framingham model and Health Services for HIV seropositive women,
Invited Speaker. National Correctional Health Care conference, Washington
DC, November 13-15 1995.
|
Reducing
the risk of tuberculosis transmission in the prison setting through
the use of environmental controls (HEPA filters and UV lights),
Invited Speaker. National Correctional Health Care conference, Washington
DC, November 13-15 1995.
|
HIV
infection in Women, Invited Speaker. Harvard AIDS Institute, Changing
Times, Changing Strategies, AIDS in New England, April 4, 1995.
|
Sexual
Abuse and HIV Risk Taking among Incarcerated Women, Invited Speaker.
HIV infection in Women, 1st National Meeting in Washington DC, February
1995.
|
Sexual
Abuse and HIV Risk Taking among Incarcerated Women, National Drug
Abuse Treatment Association conference, Newport RI, November 11, 1995.
|
Prisons:
Inside/Out Departments of Legal Studies, Political Science, and Women's
Studies, UMass Amherst. Invited speaker, panel on Economics of Prison
and Sentencing Issues, March 1996.
|
Second
Generation HIV/AIDS behind Bars, Invited speaker on panel with members
of NORA, CDC, Federal Bureau of Prisons. NCCHC conference, Nashville
Tennessee, Oct 27, 1996.
|
Sexual abuse and HIV Risk taking, Invited Speaker. Suffolk
County Jail, Massachusetts DPH HIV Case Managers meeting January 1996
and Planned Parenthood open seminar, Boston, MA, April 25, 1996.
|
1996
Prevention Summit, HIV Prevention Planning Co-Chairs Meeting, CDC,
Bethesda, Maryland, Panel, invited speaker: Effective Interventions
to prevent HIV in Correctional Facilities, Atlanta, GA, May 1996.
|
HIV
and incarcerated women: Risks, Models of Care, Invited Speaker. APHA
panel on Prisons and Jails (Socialist Caucus) APHA meeting, New York City,
November 1996.
|
Closed
Roundtable on HIV/Prison, Invited Speaker. Corrections Responds to HIV
disease among Incarcerated Women, Correctional HIV Consortium Winter Update,
San Pedro, California, January 11, 1997.
|
Intensive workshop on HIV Behind Bars: Providing Education, Advocacy,
Care and Services (Intensive workshop #1) Invited Speaker. 9th Annual
AIDS Update Conference, San Francisco, California, March,1997.
|
Care and Treatment in Prisons and Jails (Panel #406), Invited Speaker.
9th Annual AIDS Update Conference, San Francisco, California, March1997.
|
State
of the Art Workshop, Living with HIV behind prison walls: perspectives
from a patient and her physician, Invited Speaker. Women and HIV infection
Conference, Los Angeles, California, October,1997.
|
HIV
infection among incarcerated women: Clinical Care, Invited Speaker.
New England School of Law, Symposium on the Treatment of Women Prisoners
Boston, MA , January 23, 1998.
|
HIV
infection among incarcerated women, Invited Speaker. New England Medical
Center series for HIV infected Women (sponsored by AIDS Action and the
New England Medical Center) Gender Politics of HIV/AIDS in Women
Boston, MA June 19, 1998.
|
What's
different about Women living with HIV in Corrections, Invited Speaker.
(AIDS track talk on HIV infection among incarcerated women), National
Commission on Correctional Health Care (National Meeting, November1998.
|
HIV
Management in the Prison Setting: An Update, Invited Speaker. NJ AIDS
Education and Training Center and Correctional Medical Service, Newark,
New Jersey, December 12, 1998.
|
Management
of the HIV infected inmate, Invited Speaker. Delaware AIDS Council
Annual Meeting, Wilmington Delaware, November 1998.
|
|
Additional
talks on the Management of HIV in Correctional Facilities to
HIV providers on site
|
-
South Carolina Women's Facility, Columbia, South Carolina
- Central
Florida Receiving Facility, Orlando Florida, August and November 1998,
June 1999, February 2001.
- Delaware
Department of Corrections, at the Delaware AIDS Council, November 1998.
|
Policy
Action Network Briefing at the US Senate, Russell Office Building for
Senate Staffers: Breaking the Wall of Silence: Women, HIV/AIDS, and
the Prison System, Invited Speaker. Tuesday February 9, 1999.
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Prisoner
Research, Invited Speaker. CCG Scientific Agenda Subcommittee conference
call. Jeff Taylor, Chair CCG Scientific Agenda Subcommittee ACTG April
19, 2000.
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HIV
Behind Bars Director, CME acredited course for Correctional HIV providers,
June 2001, organized by Montefiore Medical Center.
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Bridging
the Gap: HIV and Hepatitis in Corrections, Organizer and speaker,
Pre-conference Symposium, National Commission on Correctional Healthcare
conference, November 2001. (Speaker: TB and Correctional Health, HIV
infection in Women, and Overview)
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Grants:
Principal Investigator
NIH and Foundation grants for research
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| 2002
To be Activated |
05/01/02
- 04/30/05 Epitope Driven HIV Vaccine Development
NIH/NIAID 1 R01 AI50528-01A1
Total Direct Costs $1,974,889; Indirect Costs Total $784,257 ( total grant
$2,759,146 )
PI: De Groot |
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| 2001-2002
Active |
07/01/01
- 12/30/01 Diagnostic Reagents for Emerging Infectious Diseases
NIH/NIAID: SBIR Phase I to EpiVax
TBHRL Total Direct Costs $40,000; Indirect Costs $22,000 (total grant $100,000)
PI: De Groot |
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12/30/01
- 08/30/02 Epitope-driven HPV Vaccine Targeting Dendritic Cells
NIH/NCI: SBIR Phase I to EpiVax
TBHRL Total Direct Costs $67,382; Indirect Costs $32,708 (total grant to
TBHRL $100,090)
PI: De Groot |
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3/1/00 -
03/1/03 Sequella Global TB Foundation
Bringing Epitope Driven Vaccines into Phase I Trials
SGTBF Core Scientist Award
Total Direct Costs $900,000 to EpiVax
TBHRL Subcontract: Total Direct Costs: $300,000 (expected/3 years); Indirect
$150,000.
PI: De Groot
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7/0/97
- 06/30/02 HIV Evolution and Cellular Immune Response
NIH: R01 AI 40888
Total Direct Costs $899,249; Indirect Costs $283,029.
PI: De Groot |
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03/01/99
- 04/30/03. Immunoregulatory Defects in Hemophelia
NIH: R01 HL 042257
Year Two Total Direct Costs $13,416; Indirect Costs $8,049
PI: John Sullivan, Umass Worcester, De Groot, subcontractor |
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