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Publications

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Azadi et al, 2012 Azadi, G., Gustafson, E., Wessel, G.M., and Tripathi, A. (2012). Rapid detection and quantification of specific proteins by immunodepletion and microfluidic separation. Biotechnology Journal, 7, 1008–1013.
Oulhen et al, 2012 Oulhen, N., Reich, A., Wong, J., and Wessel GM. (2012). Diversity in the fertilization envelope of echinoderms. Evolution and Development in press.
Song and Wessel, 2012 Song, J. and Wessel, GM. (2012). The forkhead transcription factor FoxY regulates Nanos. Molecular Reproduction and Development, 79, 680–688.
Reich et al, 2012 Reich, A., Neretti, N., Freiman, R.N., and Wessel, G.M. (2012). Transcriptome variance in single oocytes within, and between, genotypes. Molecular Reproduction and Development, 79, 502–503.
Yajima and Wessel, 2012 Yajima, M. and Wessel, G.M. (2012). Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin. Development, 139, 3786-3794.
Yajima, Fairbrother, and Wessel, 2012 Yajima, M., Fairbrother, W.G., and Wessel, G.M. (2012). ISWI contributes to ArsI insulator function in development of the sea urchin. Developmental, 139, 3613-3622.
Sutherby et al, 2012 Sutherby, J., Giardini, J-L., Nguyen, J., Wessel, G., Leguia, M. and Heyland, A. (2012). Histamine is a modulator of metamorphic competence in Strongylocentrotus purpuratus (Echinodermata: Echinoidea). BMC Developmental Biology, 12, 14-29.
Juliano, C.E., Swartz, S.Z., and Wessel, G.M. (2012). Isolating specific embryonic cells of the sea urchin by FACS. Methods in Molecular Biology: Developmental Biology of the Sea Urchin and other Marine Invertebrate Model Systems. Humana Press, in press.
Song et al, 2011 Song, J., Stoeckius, M., Maaskola, J., Friedländer, M., Stepicheva, N., Juliano, C., Lebedeva, S., Thompson, W., Rajewsky, N., Wessel, G.M. (2011). Select microRNAs are essential for early development in the sea urchin. Developmental Biology, 362, 104–111.
Yajima and Wessel, 2011c Yajima, M. and Wessel, G.M. (2011). The multiple hats of Vasa: its functions in the germline and in cell cycle progression. Mol. Reprod. Dev., 78, 861-867.
Reich et al, 2011 Reich, A., Klatsky, P., Carson, S., and Wessel, G.M. (2011). The transcriptome of a human polar body accurately reflects its sibling oocyte. JBC, 286, 40743-40749.
Yajima and Wessel, 2011b Yajima, M. and Wessel, G.M. (2011). The DEAD-box RNA helicase Vasa functions in embryonic mitotic progression in the sea urchin. Development, 138, 2217-2222.
Schmerler and Wessel, 2011 Schmerler, S. and Wessel, G.M. (2011). Polar bodies—More a lack of understanding than a lack of respect. Mol. Reprod. Dev., 78, 3–8.
Gustafson and Wessel, 2010b Gustafson, E.A. et al. (2011). Post-translational regulation by gustavus contributes to selective Vasa protein accumaulation in multipotent cells during embryogenesis. Developmental Biology, 349, 440–450.
Yajima and Wessel, 2011a Yajima, M. and Wessel, G.M. (2011). Small micromeres contribute to the germline in the sea urchin. Development, 138, 237-243.
Juliano, Swartz and Wessel, 2010 Juliano, C.E., Swartz, S.Z., and Wessel, G.M. (2010). A conserved germline multipotency program. Development, 137, 4113-4126.
Klatsky, Wessel, and Carson, 2010 Klatsky, P.C., Wessel, G.M., and Carson, S.A. (2010). Detection and quantification of mRNA in single human polar bodies: a minimally invasive test of gene expression during oogenesis. Molecular Human Reproduction, 16(12), 938-943.
Gustafson and Wessel, 2010c Gustafson, E.A. and Wessel, G.M. (2010). Exogenous RNA is selectively retained in the small micromeres during sea urchin embryogenesis. Mol. Reprod. Dev., 77, 836.
Juliano and Wessel, 2010 Juliano, C.E. and Wessel, G.M. (2010). Versatile Germline Genes. Science, 329, 640-641.
Gustafson and Wessel, 2010b Gustafson, E.A. and Wessel, G.M. (2010). Vasa genes: Emerging roles in the germ line and in multipotent cells. BioEssays, 32, 626-637.
Wessel, Reich, and Klatsky, 2010 Wessel, G.M., Reich A.M., and Klatsky P.C. (2010). Use of sea stars to study basic reproductive processes. Syst Biol Reprod Med., 56(3), 236-45.
Ruas et al, 2010 Ruas, M., et al. (2010). Purified TPC Isoforms Form NAADP Receptors with Distinct Roles for Ca2+ Signaling and Endolysosomal Trafficking Current Biology, 20, 703–709.
Wong and Wessel, 2010 Wong, J.L. and Wessel, G.M. (2010). VISIONS: the art of science. Mol Reprod Dev., 77(6), 473.
Gustafson and Wessel, 2010a Gustafson, E.A. and Wessel, G.M. (2010). DEAD-box helicases: Posttranslational regulation and function. BBRC, 395, 1-6.
Juliano and Wessel, 2009 Wessel, G.M., Juliano, C.E., Wong, J.L., Gustafson, E.A., and Song, J.L. (2010). Molecular markers of oocyte and primordial germ cell development in the sea urchin. Echinoderms, 517-528.
Juliano, Yajima, and Wessel, 2010 Juliano, C.E., Yajima, M., and Wessel, G.M. (2010) Nanos functions to maintain the fate of the small micromere lineage in the sea urchin embryo. Developmental Biology 337(2), 220-232.
Klatsky, Carson, and Wessel, 2010 Klatsky, P.C., Carson, S.A., and Wessel, G.M. (2010). Detection of oocyte mRNA in starfish polar bodies. Mol. Reprod. Dev., 77, 386.
Juliano and Wessel, 2009 Juliano, C.E., and Wessel, G.M. (2009). An evolutionary transition of vasa regulation in echinoderms. Evolution & Development 11, 560-573.
Wong and Wessel, 2009 Wong, J.L., and Wessel, G.M. (2009). Extracellular matrix modifications at fertilization: regulation of dityrosine crosslinking by transamidation. Development 136, 1835-1847.
Wessel and Wong, 2009 Wessel, G.M., and Wong, J.L. (2009). Cell surface changes in the egg at fertilization. Mol Reprod Dev 76, 942-953.
Wong and Wessel, 2008c Wong, J., Wessel, G.M. (2008). Renovation of the egg extracellular matirx at fertilization. International Journal of Developmental Biology 52, 545-550.
Davis et al., 2008 Davis LC, Morgan AJ, Ruas M, Wong JL, Graeff RM, Poustka AJ, Lee HC, Wessel GM, Parrington J, Galione A. (2008). Calcium signaling occurs via second messenger release from intraorgnaelle synthesis sites. Current Biology 18, 1612-1618.
Gustafson and Wessel, 2008 Gustafson EA, Wessel GM (2008). Polycomb group gene expression in the sea urchin. Developmental Dynamics 237, 1851-1861.
Voronina et al., 2008 Voronina E, Lopez M, Juliano CE, Gustafson E, Song JL, Extavour C, George S, Oliveri P, McClay DR, Wessel GM. (2008). Vasa protein epxression is restricted to the small micromeres of the sea urchin, but is inducible in other lineages in early development. Developmental Biology 314, 276-286.
Wong and Wessel, 2008b Wong, J., Wessel, G.M. (2008). FRAP analysis of secretory granule lipids and proteins in the sea urchin egg. Methods in Molecular Biology 440, 61-76.
Wong and Wessel, 2008a Wong, J.L., and Wessel, G.M. (2008). Free-radical crosslinking of specific proteins alters the function of the egg extracellular matrix at fertilization. Development 135, 431-440.
Wong et al., 2007 Wong, J., Koppel, D., Cowan, A, Wessel, G.M. (2007). Membrane Hemifusion Is a Stable Intermediate of Exocytosis. Developmental Cell 12, 653-659.
Song and Wessel, 2007 Song, J.L., and Wessel, G.M. (2007). Genes involved in the RNA interference pathway are differentially expressed during sea urchin development. Dev Dyn 236, 3180-3190.
Parrington et al., 2007 Parrington, J., Davis, L.C., Galione, A., and Wessel, G. (2007). Flipping the switch: how a sperm activates the egg at fertilization. Dev Dyn 236, 2027-2038.
Sodergren et al., 2006 Sodergren et.al. (2006). The Genome of the Sea Urchin Strongylocentrotus purpuratus. Science 314, 941-952.
Wong and Wessel, 2006b Wong, J. and Wessel, G.M. (2006). Rendezvin: an essential gene encoding independent, differentially secreted egg proteins that organize the fertilization envelope proteome after self-association. Mol. Biol. Cell 17, 5241-5252.
Briggs and Wessel, 2006 Briggs , E. and G.M. Wessel (2006). In the beginning …. Animal fertilization and sea urchin development. Dev. Biol.300, 15-26.
Song, Wong, and Wessel, 2006 Song , J., Wong, J., and Wessel, G.M. (2006). Oogenesis: single cell development and differentiation. Dev. Biol.300, 385-405.
Voronina and Wessel, 2006 Voronina, E., and Wessel, G.M. (2006). Activator of G-protein signaling in asymmetric cell divisions of the sea urchin embryo. Dev Growth Differ 48, 549-557.
Juliano et al., 2006 Juliano, C., Voronina, E., Stack, C., Aldrich, M., Cameron, A., and Wessel, G.M. (2006). Germ line determinants are not localized early in sea urchin development, but do accumulate in the small micromere lineage. Dev. Biol. 300, 406-415.
Roux et al., 2006 Roux, M.M. Townley, I.K., Raisch, M., Reade, A., Bradham, C., Humphreys, G., Gunaratne, H.J., Killian, C.E., Moy, G., Su, Y-H., Ettensohn, C.E., Wilt, F., Vacquier, V.D., Wessel, G.M., and Foltz, K.R. (2006). A functional genomic and proteomic perspective of sea urchin calcium signaling and egg activation. Dev. Biol. 300, 416-433.
Beane et al., 2006 Beane , W.S., Voronina, E., Wessel, G.M. and McClay, D.R. (2006). Lineage-specific expansions provide genomic complexity among sea urchin GTPases. Dev. Biol. 300, 165-179.
Leguia and Wessel, 2006 Leguia, M. and Wessel, G.M. (2006). The Histamine H1 Receptor Activates the Nitric Oxide Pathway at Fertilization. Mol. Reprod. Dev.73, 1550-1563.
Leguia et al., 2006 Leguia, M., Conner, S., Berg, L., and Wessel, G.M. (2006). Synaptotagmin I is involved in the regulation of cortical granule exocytosis in the sea urchin. Mol. Reprod. Dev. 73, 895-905.
Wong and Wessel, 2006a Wong, J. and Wessel, G.M. (2006) Defending the Zygote: Search for the Ancestral Animal Block to Polyspermy Current Topics in Developmental Biology 72, 1-151.
Wong and Wessel, 2005 Wong, J. and Wessel, G. M. (2005). Reactive Oxygen Species and Udx1 During Early Sea Urchin Development. Dev. Bio. 288, 317-333.
Song and Wessel, 2005 Song, J.L., and Wessel, G.M. (2005). How to make an egg: transcriptional regulation in oocytes. Differentiation 73, 1-17.
Voronina and Wessel, 2004 Voronina, E. and Wessel, G.M. (2004) bg subunits of heterotrimeric G-proteins contribute to Ca2+ release at fertilization in the sea urchin. Journal of Cell Science 117, 5995-6005.
Wong, Créton, and Wessel, 2004 Wong, J. L., Créton,R. and Wessel, G.M. (2004) The Oxidative Burst at Fertilization is Dependent upon Activaion of the Dual Oxidase Udx1. Dev. Cell. 7, 801-814.
Brooks and Wessel, 2004 Brooks, J. and Wessel, G.M. (2004) The major yolk protein of sea urchins is endocytosed by a dynamin-dependent mechanism. Biology of Reproduction 71, 705-713.
Voronina and Wessel, 2004 Voronina, E. and Wessel, G.M. (2004) Regulatory contribution of heterotrimeric G-proteins to oocyte maturation in the sea urchin. Mechanisms of Development 121, 247-259.
Covián-Nares et al., 2004 Covián-Nares et al (2004) A Rho-signaling pathway mediates cortical granule translocation in the sea urchin oocyte. Mechanisms of Development 121, 225-235.
Haley and Wessel, 2004b Haley, S., and Wessel, G.M. (2004) Regulated proteolysis by cortical granule serine protease1 at fertilization.Mol. Bio. of the Cell 15, 2084-2092.
Haley and Wessel, 2004a Haley, S., and Wessel, G.M. (2004) Proteolytic cleavage of the cell surface protein p160 is required for detachment of the fertilization envelope in the sea urchin. Develpmental Biology 272, 191-202.
Wong and Wessel, 2004 Wong, J., and Wessel, G.M. (2004) Major components of a sea urchin block to polyspermy are structurally and functionally conserved. Evolution and Development 6(3), 134-153.
Leguia and Wessel, 2004 Leguia, M., and Wessel, G. (2004) Selective expression of sec1/munc18 member in sea urchin eggs and embryos.Gene Expression Patterns 4, 645-657.
  Ettensohn, C.A., Wessel, G.M., and Wray, G.A. (2004). The invertebrate deuterostomes: an introduction to their phylogeny, reproduction, development, and genomics. Methods Cell Biol 74, 1-13.
  Wessel, G.M., Voronina, E., and Brooks, J.M. (2004). Obtaining and handling echinoderm oocytes. Methods Cell Biol 74, 87-114.
  Wessel, G.M., and Vacquier, V.D. (2004). Isolation of organelles and components from sea urchin eggs and embryos. Methods Cell Biol 74, 491-522.
Szule et al., 2003 Szule, J.A., Jarvis, S.E., Hibbert, J.E., Spafford, J.D., Braun, J.E.A., Zamponi,G.W., Wessel, G.M., and Coorssen, J.R. (2003) Calcium-triggered membrane fusion proceeds independently of specific presynaptic proteins. J. of Biological Chemistry 278(27), 24251-24254.
Voronina and Wessel, 2003 Voronina, E. and Wessel, G.M. (2003) The regulation of oocyte maturation. Current Topics in Developmental Biology 58, 53-110.
Voronina, Marzluff and Wessel, 2003 Voronina, E., Marzluff, W.F., and Wessel, G.M. (2003) Cyclin B synthesis is required for sea urchin oocyte maturation. Developmental Biology 256, 258-275.
Brooks and Wessel, 2003b Brooks, J.M. and Wessel, G.M. (2003) A diversity of yolk protein dynamics and function. Recent Devel. Cell Res. 1, 1-30.
Brooks and Wessel, 2003 Brooks, J. and Wessel, G.M. (2003) Selective transport and packaging of the major yolk protein in the sea urchin. Developmental Biology 261, 353-370.
Brooks and Wessel, 2002 Brooks, J.M., and Wessel, G.M. (2002) The major yolk protein in sea urchins is a transferrin-like, iron binding protein. Dev. Bio. 245, 1-12.
Wessel, Conner and Berg, 2002 Wessel, G.M., Conner, S.D., and Berg, L. (2002) Cortical granule translocation is microfilament mediated and linked to meiotic maturation in the sea urchin. Development 129, 4315-4325.
Moore et al., 2002 Moore et al (2002) Cyclin D and cdk4 are required for normal developmetn beyond the blastula stage in sea urchin embryos. Mol. and cell Bio. 22(13), 4863-4875.
Voronina and Wessel, 2001 Voronina, E. and Wessel, G.M. (2001) Apoptosis in sea urchin oocytes, eggs and early embryos. Mol. Repro. and Dev. 60, 553-561.
Wessel et al., 2001 Wessel, G.M., Brooks, J.M., Green, E., Haley, S., Voronina, E., Wong, J., Zayfudim, V., & Conner, S. (2001) The Biology of Cortical Granules. International Review of Cytology
Conner and Wessel, 2001 Conner, S., and Wessel, G. (2001) Syntaxin, VAMP, and Rab3 are selectively expressed during sea urchin embryogenisis.Mol. Repro. Dev. 58, 22-29.
Wessel et al., 2000 Wessel, G.M., Zaydfudim, V., Hsu, Y.J., Laidlaw, M., and Brooks, J.M.(2000) Direct molecular interaction of a conserved yolk granule protein in sea urchins Develop. Growth Differ. 42, 507-517.
Gross et al., 2000 Gross, V.S., Wessel, G., Florman, H.M., and Ducibella, T. (2000). A monoclonal antibody that recognizes mammalian cortical granules and a 32-kilodalton protein in mouse eggs. Biol Reprod 63, 575-581.
Moreno et al., 2000 Moreno, R.D., Ramalho-Santos, J., Chan, E.K., Wessel, G.M., and Schatten, G. (2000) The Golgi Apparatus Segregates from the Lysomal/Acrosomal Vesicle during Rhesus Spermiogenesis: Structural Alterations. Dev Bio 219, 334-349.
Ramalho-Santos et al., 2000 Ramalho-Santos, J., Moreno, R.D., Sutovsky, P., Chan, A.W., Hewitson, L., Wessel, G.M., Simerly, C.R., and Schatten, G. (2000) SNAREs in Mammalian Sperm: Possible Implications for Fertilization. Dev Bio 223, 54-69.
Wessel et al., 2000 Gary M. Wessel, Sean Conner, Michael Laidlaw, Jacob Harrison, and Gary J. LaFleur, Jr. (2000) SFE1, a Constituent of the Fertilization Envelope in the Sea Urchin Is Made by Oocytes and Contains Low-Density Lipoprotein-Receptor-Like Repeats. Bio. of Reprod. 63, 1706-1712.
Conner and Wessel, 2000 Conner, S.D., and Wessel, G.M. (2000) A rab3 homolog in sea urchin functions in cell division. FASEB 14, 1559-1566.
Ramalho-Santos et al., 2000 Ramalho-Santos, J., Sutovsky, P.,Simerly, C., Oko, R., Wessel, G.M., Hewitson, L.,& Schatten, G. (2000) ICSI choreography: fate of sperm structures after monospermic rhesus ICSI and first cell cycle implications. Human Reproduction 15, 2610-2620.
Conner and Wessel, 1999 Conner, S.D., and Wessel, G.M. (1999) Syntaxin Is Required for Cell Division. Mol. Biol. Cell 10, 2735-2743.
Wessel and Wikramanayake, 1999 Wessel, GM and Wikramanayake, A (1999) How to grow a gut: ontogeny endoderm in the sea urchin embryo. Bioessays 21, 459-471.
Haley and Wessel, 1999 Haley, S., and Wessel, G. (1999) The Cortical Granule Serine Protease CGSP1 of the Sea Urchin, Stongylocentrotus purpuratus Is Autocatalytic and Contains a Low-Density Lipoprotein Receptor-like Domain. Dev. Bio. 211, 1-10.
Wessel et al., 1998 Wessel, G.M., et al (1998) A molecular analysis of hyalin-a substrate for cell adhesion In the hyaline layer of the sea urchin embryo. Dev. Bio. 193, 115-126.
LaFleur et al., 1998 LaFleur, G.J., Horiuchi, Y., and Wessel, G.M., (1998) Sea Urchin Ovoperoxidase: Oocyte-specific Member of a Heme-dependent Peroxidase Superfamily that Functions In the Block to Polyspermy. Mech. of Dev. 70, 77-89.
Conner and Wessel, 1998 Conner, S., and Wessel, G. (1998) rab3 mediates cortical granule exocytosis in the sea urchin egg. Dev. Bio. 203, 334-344.
Edelmann et al., 1998 Edelmann, L., Zheng, L., Wang, Z.F., Marzluff, W., Wessel, G.M., and Childs, G. (1998). The TATA binding protein in the sea urchin embryo is maternally derived. Dev Biol 204, 293-304.
Conner et al., 1997 Conner, S., Leaf, D., and Wessel, G.M., (1997) Members of the SNARE hypothesis are associated with cortical granule exocytosis in the sea urchin egg. Mol. Repro. Dev. 48, 1-13.
Schulz, Wessel, and Vacquier, 1997 Schulz, J., Wessel, G., Vacquier, V. (1997) The exocytosis regulatory proteins syntaxin and VAMP are shed from sea urchin sperm during the acrosome reaction. Dev. Bio. 191, 80-87.
Berg and Wessel, 1997 Berg, LK and Wessel, GM (1997) Cortical granules of the sea urchin translocate early in oocyte maturation. Development 124, 1845-1850.
Berg, Chen and Wessel, 1996 Berg, L., Chen, S.W. and Wessel, G.M. (1996) An extracellular matrix molecule that is selectively expressed during development is important for gastrulation in the sea urchin embryo. Development 122, 703-713.
Chen and Wessel, 1996 Chen, S.W. and Wessel, G.M. (1996) Endoderm differentiation in vitro identifies a transitional period for endoderm ontogeny in the sea urchin embryo. Dev Biol 175:57-65.
Wessel and Berg, 1995 Wessel, G.M. and Berg, L. (1995) A spatially restricted molecule of the extracellular matrix is contributed both maternally and zygotically in the sea urchin embryo. Devel Growth Diff 37, 517-527.
Wessel, G., Clark, F., and Berg, L. (1995) A diversity of enzymes involved in the regulation of reversible tyrosine phosphorylation in sea urchin eggs and embryos. Comp Biochm Phys 110, 493-502.
Holy et al., 1995 Holy, J., Wessel, G., Berg, L., Gregg, R., and Schatten, G. (1995) Molecular characterization and expression patterns of a B-type nuclear lamin during sea urchin embryogenesis. Devel Biol 168, 464-478.
Wessel, 1995 Wessel, G.M. (1995) A protein of the sea urchin cortical granules is targeted to the fertilization envelope and contains an LDL-receptor-like motif. Devel Biol 167, 388-397.
Laidlaw and Wessel, 1994 Laidlaw, M. and Wessel, G.M. (1994) Cortical granule biogenesis is active throughout oogenesis in sea urchins. Development 120, 1325-1333.
Wessel, G. and Chen, S. (1993) Transient, localized accumulation of a-spectrin during sea urchin morphogenesis. Devel Biol 155, 161-171.
Wessel, G.M. (1993) Differentiation of the endodermal epithelium during gastrulation in the sea urchin embryo. In Molecular Basis of Morphogenesis (ed. M. Bernfield), Wiley-Liss, Inc., 255-266.
Wessel, G.M., Etkin, M., and Benson, S. (1991). Primary mesenchyme cells of the sea urchin embryo require an autonomously produced, nonfibrillar collagen for spiculogenesis. Dev Biol 148, 261-272.
Wessel, G.M., Zhang, W., and Klein, W.H. (1990). Myosin heavy chain accumulates in dissimilar cell types of the macromere lineage in the sea urchin embryo. Dev Biol 140, 447-454.