Faculty Profile: Ronald Cohen, PHD, ABPP, ABCN

Ronald Cohen, PHD, ABPP, ABCN
Adjunct Professor of Psychiatry & Human Behavior
Psychiatry & Human Behavior
Work: +1 401-793-8787
Ronald Cohen is an active researcher in clinical and cognitive neuroscience with over 100 publications. He has authored the book Neuropsychology of Attention, and co-authored a book on Vascular Dementia. His research interests include the study of brain-behavior relationships, particularly with respect to attention, timing, and executive functioning. His clinical research interests include the neural bases of violence, cardiovascular disease influences on neurocognitive functioning, and Alzheimer's and related dementia. Recent work has been initiated to examine neurobehavioral effects of brain nicotinic function.

Biography

Ronald Cohen, PhD, is an associate professor of psychiatry and human behavior at Brown Medical School and The Miriam Hospital and director of neuropsychology at The Miriam Hospital. Cohen is an active researcher in clinical and cognitive neuroscience with over 50 publications. He has authored the book Neuropsychology of Attention. His research interests include the study of brain-behavior relationships, particularly with respect to attention, timing, and executive functioning. His clinical research interests include the neural bases of violence, cardiovascular disease influences on neurocognitive functioning, and Alzheimer's and related dementia. Recent work has been initiated to examine neurobehavioral effects of brain nicotinic function. Cohen is actively involved in the training of interns and postdoctoral fellows within the Centers.

Institutions

Mh

Research Description

Ronald Cohen's research interests are brain-behavior relationships, particularly with respect to attention, timing, and executive functioning. Research has focused on interface between attentional systems of the brain and emotional/motivational systems. Specific focus on the role of the anterior cingulate cortex for intentional processes and in the modulation of stress.

Clinical research interests include the neural bases of violence, cardiovascular disease influences on neurocognitive functioning, and Alzheimer's and related dementia. He has conducted numerous studies of brain dysfunction associated with HIV. Recent work has been initiated to examine neurobehavioral effects of brain nicotinic function on reward and attention systems of the brain in the context of smoking behavior.

Over the past decade, Cohen's research has increasingly focused on the use of brain imaging methods to study the questions discussed above. This includes studies that employ functional MRI, diffusion tensor MRI, MR spectroscopy, and brain morphometry methods.

Grants and Awards

Diplomate, American Board of Professional Psychology
Diplomate, American Board of Clinical Neuropsychology

Affiliations

American Psychological Association
American Board of Clinical Neuropsychology
Americal Board of Professional Psychology
International Neuropsychological Society
American Neuropsychiatric Association
Society for Neuroscience
National Institute of Health, Behavioral Medicine Interventions and Outcomes (BMIO) Institutional Review Group

Funded Research

PENDING
1. "Age Effects on HIV-Associated Brain Dysfunction"
PI
National Institutes of Health (NIH)
7/1/06-6/30/11
First Year Directs: $268,952

2. "Cognitive Effects of Bariatric Surgery"
PI: John Gunstad, Ph.D.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)/ Subcontract from Kent State
12/1/06-11/30/10
First Year Directs: $18,123

ACTIVE
1. National Institute of Neurological Disorders and Stroke (NINDS) $23,269
(Brad Navia, PI)
5/31/05-6/1/10
"Proton MRS studies of cerebral injury in HIV infection"

2. National Cancer Institute (NCI) P50 CA84719-05 $1,406,084
9/30/04-9/29/09
"Nicotine Dependence: Phenotype, Endophenotype & Contexts"
Project 2 goal is to understand the genetic and brain bases of nicotine craving

3. National Heart Lung and Blood Institute (NHLBI) 4 RO1 $124,314
(Mark Aloia, PhD, PI)
7/01/04-06/30/08
"Subcortical hyperintensities in sleep apnea syndrome"
The study goal is to better understand the relationship of subcortical brain changes to sleep apnea and specific vascular risk factors. Dr. Cohen oversees brain morphometry analyses of SH.

4. National Institute of Aging (NIA) U01 AG10483 $55,700
(Brian Ott, PI)
3/21/03 – 8/31/06
"A Multi-center, Randomized, Double-blind, Placebo Controlled Trial of Simavastin to Slow the Progression of Alzheimer's Disease »
This multi-center trial is designed to test the effects of statin, a cholesterol lowering drug in the treatment of AD. The rationale is that such intervention may slow the rate of disease progression.

5. NIA Protocol 40-VN $94,250
(Brian Ott, PI)
7/1/03-6/30/06
"A Randomized, Double-blind, Placebo-controlled Trial of Valproate to Attentuate the Progression of Alzheimer's Disease"

6. NIA 6 R01 AG017975-05 (Ronald Cohen, PI) $250,000
6/15/00-5/31/06
"Heart Disease, CNS Dysfunction & Outcome in the Elderly"
The project goal is to better understand the effects of specific vascular factors on the development of cardiovascular, cerebrovascular, & neurocognitive dysfunction, and to determine how such changes effect clinical outcome, health status, and quality of life over time

PREVIOUS
1. NIA RO1 $1,250,000
2000-2004
Neurocognitive effects of cardiovascular disease in the elderly.

2. National Institute of Drug Abuse (NIDA) (ISTART grant) $100,000.
Co-Investigator, (Tara White, PI)
An fMRI study of cocaine effects on impulsivity.

3. National Institute of Allergy and Infectious Diseases (NIAID) Supplemental developmental grant to the Brown University Center for AIDS Research (CFAR) Supplement $60,000
(CFAR: PI-Charles Carpenter, MD)
2001-2002
HAART adherence and neurocognitive functioning among HIV-infected elderly.

4. NIH $60,000
Co-Investigator
2000-2001
Alzheimer's Disease Cooperative Study: A multicenter trial of rofecoxib and naproxen in Alzheimer's Disease

5. Interneuron Pharmaceutical Corp. IP302-012 $198,000
1997-2000
The effects of citicolinee in the treatment of vascular dementia

Selected Publications

  • Zawacki, T., Cohen, R., Paul, R., Moser, D., & Grace J. (in press). Relationship between apathy and activities of daily living in vascular- dementia. Journal of Neuropsychiatry and Clinical Neurosciences. (IN PRESS)
  • Paul, R., Cohen, R., Navia, B., & Tashima, K. (in press). Relationships between neuropsychological function and neuroimaging in adults with human immunodeficiency virus type 1. Neuroscience and Biobehavioral Reviews. (IN PRESS)
  • Paul, R., Cohen, R., Moser, D., Ott, B. R., & Zawacki, T. (in press). Sensitivity and specificity of the Dementia Rating Scale in vascular dementia. Cerebrovascular Diseases. (IN PRESS)
  • Paul, R., Cohen, R., & Gilchrist, J. (in press). Relationship between fatigue and cognitive function in myasthenia gravis. Journal of Clinical Neuroscience. (IN PRESS)
  • Cohen, R., Paul, R., Moser, D., & Zawacki, T. (in press). The impact of subcortical hyperintensities on cognitive function in vascular dementia. Journal of the International Neuropsychological Society. (IN PRESS)
  • Cohen, R., Paul, R., Blum, V., Zawacki, T., & Sweet, L. (in press). The effects of cingulotomy on attentional and emotional function in chronic pain patients. Emotion. (IN PRESS)
  • Boyle, P., Paul, R., Ott, B., Cohen, R., & Moser, D. (in press). Subcortical hyperintensities and cognitive function predict activities of daily living in vascular dementia. Journal of Geriatric Psychiatry. (IN PRESS)
  • Paul, R., Nash, J. M., Cohen, R., & Gilchrist, J. M. (2002). Quality of life in two samples of myastehnia gravis patients. Muscle and Nerve, 25, 467-468. (2002)
  • Paul, R., Cohen, R., Moser, D., & Zawacki, T. (2002). Validity of the Global Deterioration Scale in vascular dementia. Journal of Geriatric Psychiatry and Neurology, 15, 50-54. (2002)
  • Paul, R., Cohen, R., Moser, D., & Ott, B. (2002). The serial position effect in vascular dementia. Journal of the International Neuropsychological Society, 8, 584-587. (2002)
  • Boyle, P. A., Cohen, R., Paul, R., Moser, D., & Gordon, N. (2002). Cognitive and motor impairments predict functional declines in patients with vascular dementia. International Journal of Geriatric Psychiatry, 17, 164-169. (2002)
  • Paul, R., Nash, J. M., Cohen, R., Gilchrist, J., & Goldstein, J. (2001). Quality of life in patients with myasthenia gravis. Muscle and Nerve, 24, 512-516. (2001)
  • Paul, R., Cohen, R., Ott, B. R., Zawacki, T., Moser, D., & Gordon, N. (2001). Cognitive and functional capacity in two subtypes of vascular dementia. Neurorehabilitation, 15, 199-205. (2001)
  • Paul, R., Cohen, R., Ott, B. R., Zawacki, T., & Gordon, N. (2001). Performance on the Hooper Visual Organization Test in vascular dementia: Relationship to naming. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 14, 93-97. (2001)
  • Paul, R., Cohen, R., Ott, B. R., Moser, D., & Zawacki, T. (2001). Performance on the Dementia Rating Scale in vascular dementia: Relationship to neuroimaging findings. Journal of Geriatric Psychiatry and Neurology, 14, 33-36. (2001)
  • Paul, R., Cohen, R., Moser, D., Ott., B., & Gordon, N. (2001). Pattern of neuropsychological function in vascular dementia. Effect of dementia severity. Applied Neuropsychology, 8, 211-217. (2001)
  • Paul, R., Cohen, R., Goldstein, J., & Gilchrist, J. (2001). Severity of mood, self-evaluative, and vegetative symptoms of depression in myasthenia gravis. Journal of Neuropsychiatry and Clinical Neurosciences, 12, 499-501. (2001)
  • Paul, R., Cohen, R., Gilchrist, J., Zawacki, T., & Aloia, M. (2001). What have we learned about cognitive function in myasthenia gravis: A review of methods and results. Neuroscience and Biobehavioral Reviews, 25, 75-81. (2001)
  • Moser, D., Cohen, R., Paul, R., Gordon, N., & Ott, B. R. (2001). Relationship of executive deficits to subcortical hyperintensities in vascular dementia. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 14, 89-92. (2001)
  • Cohen, R., Paul, R. H., Zawacki, T. M., Sethi, M., Ott, B. R., Moser, D. J., Stone, W., Noto, R., & Gordon, N. (2001). Single photon emission computed tomography, magnetic resonance imaging hyperintensity, and cognitive impairments in patients with vascular dementia. Journal of Neuroimaging, 11, 253-260. (2001)
  • Cohen, R., Paul, R., & Lohr, I. (2001). Impairments of attention in patients with major affective disorder. Journal of Neuropsychiatry and Clinical Neurosciences, 13, 385-395. (2001)
  • Cohen, R., Boland, R., Paul, R., Tashima, K., Schoenbaum, E. E., Celentano, D. D., Schuman, P., Smith, D. K., & Carpenter, C. (2001). Neurocognitive performance enhanced by highly active antiretroviral therapy in HIV-infected women. AIDS, 15, 341-345. (2001)