Faculty Profile: Ronald Delellis

Ronald Delellis
Ronald Delellis
Professor of Pathology & Laboratory Medicine
Pathology & Laboratory Medicine
Work: +1 401-444-5154
The research interests of Dr. Ronald DeLellis are in:
• The biology of thyroid cancer;
• Multiple endocrine neoplasia syndromes/clinical and molecular features;
• Immunohistochemical and in situ hybridization methodologies/applications in surgical pathology and cytopathology.

Biography

Dr. Ronald DeLellis is Pathologist-in-Chief of the Lifespan Academic Medical Center, which encompasses Rhode Island Hospital and The Miriam Hospital, Director of the Molecular Pathology Core for the COBRE Center for Cancer Research Development, and Professor of Pathology and Associate Chairman of the Department of Pathology and Laboratory Medicine at Brown University School of Medicine. He has held these positions since 2001 when he relocated to Rhode Island from New York where he was Vice Chairman and Director of Anatomic Pathology at The New York Hospital-Cornell Medical Center and Professor of Pathology at Cornell University Medical College since 1998. Dr. DeLellis received his M.D. degree from Tufts University School of Medicine in Boston and completed his residency training in pathology at the Massachusetts General Hospital and National Cancer Institute. His subspecialty is in the area of endocrine pathology.

Research Description

Research Interests:
• The biology of thyroid cancer;
• Multiple endocrine neoplasia syndromes/clinical and molecular features;
• Immunohistochemical and in situ hybridization methodologies/applications in surgical pathology and cytopathology.

Research/Molecular Pathology Core Facility:
Under my direction and that of the Co-director, Dr. Murray Resnick, the Molecular Pathology Core facility provides state-of-the-art instrumentation and support personnel for the research efforts of the Department of Pathology staff, members of the COBRE Center for Cancer Research Development, and academic community. To date, a total of 32 research groups have made use of our services and facilities, which includes laser capture microdissection, real time PCR, immunohistochemistry, biostatistics, data and image analysis, and a tissue bank that contains both normal and tumor tissue from more than 600 patients.

Grants and Awards

1965 Election to Alpha Omega Alpha
1966 Graduation cum laude, Tufts University School of Medicine
1972 Diplomate American Board of Pathology (Anatomic Pathology)
1980-1994 Tufts University Teaching Awards
1984 Boroughs Wellcome Visiting Professorship in Pathology at Howard University, Washington, D.C.
1988-1992 Council Member, Histochemical Society
1989 Appointment to Editorial Advisory Board, Armed Forces Institute of Pathology, Tumor Fascicle Series
1990-1996 American Board of Pathology, Anatomic Pathology Test Committee
1991 Short Course Faculty Recognition Award, U.S. and Canadian Academy of Pathology
1991-1992 President, New England Society of Pathologists
1992 Education Committee Recognition Award, U.S. and Canadian Academy of Pathology
1992 Recognition Award, U.S. and Canadian Academy of Pathology Long Course on Pathobiology of the
Thyroid and Parathyroid Glands (Co-Director with V.A. LiVolsi)
1992 Recognition Award, U.S. and Canadian Academy of Pathology Education Committee
1994-1997 Council Member, US and Canadian Academy of Pathology
1997 Distinguished Professor, Tufts University School of Medicine
1999-present Vice President Society for Applied Immunohistochemistry
1999 Fred Stewart Award, Memorial Sloan Kettering Cancer Center
1999-2000 Nominating Committee, New York Pathological Society
1999-2000 President, Endocrine Pathology Society (USCAP)
2001-2002 President, U.S. and Canadian Academy of Pathology
2005 Mostofi Distinguished Service Award, US and Canadian Academy of Pathology

Affiliations

Professional Memberships:
Alpha Omega Alpha
Histochemical Society
Massachusetts Society of Pathologists
New England Society of Pathologists
American Association for Investigative Pathology
United States and Canadian Academy of Pathology
Arthur Purdy Stout Society of Surgical Pathologists
New York Pathological Society

Editorial Boards:
American Journal of Surgical Pathology
Ultrastructural Pathology
Advances in Anatomic Pathology
Human Pathology
Journal of Histochemistry and Cytochemistry
Modern Pathology
Applied Immunohistochemistry and Molecular Morphology
International Journal of Surgical Pathology
Histochemical Journal
Co-Editor, Diagnostic Molecular Pathology

Committees:
1985–present Short Course Director, US and Canadian Academy of Pathology
1985-1992 Executive Committee, New England Society of Pathologists
1988-1992 Histochemical Society (Council Member)
1989-present Editorial Advisory Board, Armed Forces Institute of Pathology, Fascicle Series
1990-1996 American Board of Anatomic Pathology Test Committees
1994-1997 Council Member, US and Canadian Academy of Pathology
1998-present Appointment to Board, Society for Applied Immunohistochemistry
1998-1999 Publications Committee, US and Canadian Academy of Pathology
2000-2004 Executive Committee, US and Canadian Academy of Pathology
2001-present Intersociety Pathology Council
2003–present WHO Project on Classification of Endocrine Tumors
2002–present American Registry of Pathology (Board Member)
2002–2004 College of American Pathologists (Surgical Pathology Committee)
2002–2004 College of American Pathologists (Cell Marker Committee)

Funded Research

1974-1980 Public Health Service Grant, National Cancer Institute, CA 17389
"C-Cell Hyperplasia and Medullary Carcinoma of the Thyroid"
Ronald A. DeLellis, M.D. and Hubert J. Wolfe, M.D. (Co-Principal Investigators)
$750,000 (15% effort)

1980-1986 Public Health Service Grant, National Cancer Institute, CA 12924
"Biology of the Normal and Neoplastic C-Cell"
Ronald A. DeLellis, M.D. and Hubert J. Wolfe, M.D. (Co-Principal Investigators)
$950,000 (15% effort)

1985-1988 Public Health Service Grant, National Cancer Institute, CA 17983
"Clinical Cancer Education Program"
Larry Nathanson, M.D. (Principal Investigator), Ronald A. DeLellis, M.D (Co-Investigator)
$1,500,000 (5% effort)

1981-1983 Public Health Service Contract, NCI-CM-67072
"Classification of Non-Hodgkin's Lymphomas"
Richard Rudders, M.D. (Principal Investigator), Ronald A. DeLellis, M.D. (Co-Investigator)
$350,000, (5% effort)

1983-1986 Public Health Service Contract, CA 30335
"Immunohistochemical Profile and Survival in Breast Carcinoma"
Arthur K. Lee, M.D. (Principal Investigator), Ronald A. DeLellis, M.D., (Co-Investigator)
$400,000 (10% effort)

2002-2007 COBRE Center for Cancer Research Development, Molecular Pathology Core, 5-year grant
Ronald A. DeLellis, M.D., (Principal Investigator of Core)
$675,163 (5% effort)

Teaching Experience

Invited Lectures and Presentations: 1. Nassau County Society of Pathology (N.Y.) 10/98 "Pathology of Hyperparathyroidism" "Medullary Thyroid Carcinoma" 2. California Society of Pathology. San Diego, CA. 11/98 "Multiple Endocrine Neoplasia Syndromes" 3. Memorial Sloan Kettering Cancer Center, Thyroid 1/99 Conference "Familial Medullary Thyroid Carcinoma" 4. USCAP San Francisco, CA 3/99 "Short Course on Tumors of the Neuroendocrine System" 5. Memorial Sloan Kettering Cancer Center,Head and Neck 4/99 Grand Rounds, NY, NY "Medullary Thyroid Carcinoma" 6. New York Presbyterian Hospital, Department of Surgery 5/99, Grand Rounds "Medullary Thyroid Carcinoma" 7. New York Presbyterian, Department of Pathology 5/99 Grand Rounds "Neuroendocrine Tumors" 8. NYU – Mt Sinai Medical Center 5/99 "Visiting Professor in Department of Pathology" 9. Mt. Sinai Medical Center 5/99 "Neuroendocrine Tumors" (Residents' Day Presentation) 10.United Hospital Center Sixth Annual Seminar 5/99 in Pathology. Pittsburgh, PA "Seminar on Tumors of the Thyroid and Adrenal" 11.New York University Surgical Pathology Course 10/99 Moderator of Head and Neck Pathology Section of Course and Lecturer (Papillary lesions of the thyroid) 12.University of Sassari-Sardinia 10/99 Symposium on Tumors of the Endocrine System 13.USCAP. Pathology of the Endocrine System 3/00 (Moderator). Endocrine Pathology Society 14.Arthur Purdy Stout Society (USCAP). 3/00 Pathology of the Parathyroid 15.Academic Medical (Rhode Island Hospital, Providence, RI 8/00 16. International Academy of Pathology, Symposium on Endocrine Tumors, Nagoya, Japan 10/00 17. Korea University Medical Center Symposium on Endocrine Tumors, Seoul, Korea 10/00 18. New Jersey Society of Pathology 11/00 Thyroid Tumors 19. New England Pathology Residents Society 4/01

Selected Publications

  • Chen X, Hoda SA, DeLellis RA, Seshan SV. Lupus Mastitis. Breast J 2005 Jul-Aug; 11:283-4. (2005)
  • DeLellis, RA. Parathyroid carcinoma. An overview. Adv. Anat Pathol 2005; 12:53-61. (2005)
  • Lloyd, RV, Erickson, LA, Casey, MB, Lem, KY, Lohse, CM, Asa, Sl, Chan, JKC, DeLellis, RA, Harach, HR, Kekudo, K, LiVolsi, VA, Rosai, J, Sebo, TJ, Sobrinho-Simoes, M, Wenig, BM, Lae, ME. Observer variations in the diagnosis of follicular variant of papillary thyroid carcinoma. Am J Surg Pathol 2004; 48: 1336-1340. (2004)
  • Fischer, AH, Young, KA, DeLellis, RA. Incorporating pathologists' criteria of malignancy into the evolutionary model for cancer development. J Cel Biochem 2004; 93 28-36. (2004)
  • Ghannoum, JF, DeLellis, RA, Shin, SJ. Primary carcinoid tumor of the prostate with concurrent adenocarcinoma. Int J Surg Pathol 2004; 12: 167-170. (2004)
  • DeLellis, RA, Xia, L. Paraneoplastic endocrine syndromes: A review. Endocrine Pathol 2003;14:303-317. (2003)
  • DeLellis, RA, Shin, SJ. Immunohistochemical characteristics of adrenocortical carcinoma: An overview. Acta Histochem Cytochem 2003; 36: 293-298. (2003)
  • Khan, A., Tischler, AS, Patwardhan, NA, DeLellis, RA. Calcitonin immunoreactivity in neoplastic and hyperplastic parathyroid glands: an immunohistochemical study . Endocrine Pathol 2003;14:249-256. (2003)
  • Chen. X., DeLellis, RA, Hoda, SA. Adrenoleukodystrophy. Arch Pathol Lab Med 2003; 127:119-20. (2003)
  • Yao, D, Hoda, S, Yin, DY, Kuhel, WI, Harigopal, M, Resetkova, E, Delellis, RA. Interpretative problems and preparative technique influence reliability of intraoperative parathyroid imprint. Arch Pathol Lab Med. 2003; 127: 64-67. (2003)