Alex J. Loosley
Phone (Lab): 401-863-1405
Alex Loosley hails from Simon Fraser University (SFU) where he earned a B.Sc. in Physics and a minor in Business. During his senior year, he studied the role of positive feedback in biological oscillators with Prof. Eldon Emberly. Alex recently completed his Ph.D at Brown University under supervision and tutelage from Prof. Jay Tang's and Prof. Jonathan Reichner studying cellular traction forces and effects of substrate rigidity on cell motility and function.
Simon Fraser University (2003-2008) - B.Sc. - Physics
Brown University (2009-2014) - Sc.M / Ph.D. - Physics
Mechanobiology and Mechanical Models of Cell Locomotion
Nonlinear Dynamics in Biological Systems
- BPS Annual Meeting @ San Francisco, 2014.
Quantification of Directional Motility by a Characteristic Directionality Time.
- BPS Mechanobiology @ MDIBL, 2013.
Human Neutrophil Chemotaxis is a Function of Matrix Composition and Stiffness.
- Xian M. O'Brien, Alex J. Loosley, Katie E. Oakley, Jay X. Tang, and Jonathan S. Reichner.
Technical Advance: Introducing a novel metric, directionality time, to quantify human neutrophil chemotaxis as a function of matrix composition and stiffness.
J Leukocyte Biol, 95: 993-1004 (2014)
- Alex J. Loosley and Jay X. Tang.
Stick-slip motion and elastic coupling in crawling cells.
Phys Rev E, 86: 031908 (2012)
- Directed Migration Class - used for random walk simulations and kinematic analysis of cell motion
Videos and Raw Data