Research

Sickle cell step

A computer simulation shows the relative stickiness of SS2 and sickle cells. Credit: Karniadakis lab/Brown University

Using powerful computer models, researchers from Brown University have shown for the first time how different types of red blood cells interact to cause sickle cell crisis, a dangerous blockage of blood flow in capillaries that causes searing pain and tissue damage in people with sickle cell disease.