Research

Questions for Lance Dworkin: Stents aren’t more help for renal artery stenosis

Lance Dworkin

“Besides just answering this question about whether the stenting is useful, we’ve sort of established what could become the standard medical approach to treating these patients.”

Renal artery stenosis, a narrowing of arteries that lead to the kidneys because of athlerosclerosis, affects millions of Americans. Doctors have disagreed about how to treat it. Results from the CORAL clinical trial, simultaneously published in the New England Journal of Medicine and presented at the annual meeting of the American Heart Association Nov. 18, 2013, show there is no additional long-term benefit to inserting a stent in patients who are provided a good regimen of drug and medical therapies. The randomized, controlled study involving nearly 1,000 patients at more than 100 sites may settle disagreements about treatment.