REFERENCES for May
18, 2000
Christopher
C. Randolph, M.D.
Associate Clinical Professor
of Pediatrics
Yale University School
of Medicine
1.Landwehr LP,Boguniewicz M.Medical progress:Current perspectives in
latex allergy.JPed1996;128(3):305-12.
2.Ownby D.Clinical manifestations of latex allergy .Current Views
in Allergy Immunology November 1999Med College Georgia.
3.De Livoniere H.Industrial material rubber collection
and control procedures.Clin Rev Allergy 1993;11:309-23.
4.Nutter AF.Contact urticaria to rubber .Br J Dermatol 1979;101:597-8
5.Kwittken PL,Sweinberg SK.Childhood latex allergy: an overview.Am
J Asthma, Allergy Pediatric 1992;6:27-33.
6 Slater JE.Rubber anaphylaxis.N Eng J Med1989;320:1126-30
7.Taylor JS,Cassettari J,Wagner W,HelmsT.Contact urticaria and anaphylaxis
to latex.J Am Acad Dermatol 1989;21:874-7
8.Turjanmaa K,Reunala T.Condoms as a source of latex allergen and
cause of contact urticaria.Contact Dermatitis.1989;20:360-4.
9.Laurent J,Malet R ,SmiijanJM,at alLatex hypersensitivity after
natural delivery.J Allergy Clin Immunol 1992;89:772-90.
10.Matthew SW,Melton AL,Wagner WO.Latex hypersensitivity:a case
study.Ann Allergy 1990;70:483-6.
11.Ownby DR,Tomolanovich M,Sammons N.Anaphylaxis associated with
latex allergy during barium enema examination.AJR.Am J Roentgenol.1991;156:903-8.
12.SondheimerJM,Pearlman DS,Bailey C.Systemic anaphylaxis during
rectal manometrywith latex balloon Am J Gastroenterol 1989;84:975-7.
13.Kelly KJ,Pearson MI,Kurup VP et al.A cluster of anaphylactic
reactions in children with spina bifida during general anesthesia: epidemiological
features,risk factors ,and latex hypersensitivity.J Allergy Clin Immunol
1994;94:53-61.
14.Kelly KJ Latex Allergy .Medical College of Wisconsin CME1999
Cr.Educ.Options
15.Schwartz HA,Zurowski D.Anaphylaxis to latex in intravenous fluids.J
Allergy Clin Immunol1993;92:358-9
16.Levy A.Latex allergy.Clin Rev All1993;11:293-8
17.Von Hintzenstern J,Heese A,Koch H et al .Frequency ,spectrum
and occupational relevance of type IV allergies to rubber chemicals.Contact
Dermatitis 1991;24:244-50.
18.Yunginger JW,JonesRT,Fransway AF et al.Latex allergen:contents
of medical and consumer products.Abstract.J AllClin Immnol1993;91:241.
19.Tarlo S.Control of airborn latex by use of powder-free latex
gloves.J All Clin Imm 1994:93:985-9
20. Tarlo SM,Sussman GL,HolnessDL.Latex sensitivity in dental students
and staff :A cross- sectional study .J Allergy Clin Immunol 1997 ;99:396-401.
21.Slater JE.Latex allergy J Allergy Clin Immunol1994;94:139-49.
22.Alenius H,Palosuo T.,Kelly K et al.IgE reactivity to14kDand 27kD
natural rubber protein in latex allergic children with Spina bifida
and other congenital anomalies .Int Arch Allergy Immunol 1993 ;102:61-6.
23.Downing,JG.Dermatitis from rubber gloves .N Engl J Med
1933 ;208:196-8.
24.Schwartz HJ.Latex :a potential hidden “food”allergen in fast
food restaurants .J
Allergy Clin Immunol 1995;95:139-40.
25.Shah S,Cawley M,Gleeson R,O’Connor,J et al.Latex allergy and
latex sensitization in children and adolescents with myelomeningocele.J
Allergy Clin Imm 1998;101:741-6.
26.Sussman GI ,Tarlo S Dolovitch J.The spectrum of IgE mediated
responses to latex. JAMA1991;265:2844-7.
27.Sussman GL,Liss GM,Deal K,Brown S,Cividino M et al.Incidence
of latex sensitization among latex glove users.J Allergy Clin Immunol 1998;101:171-8.
28.Tarlo SM,Wong L,Roos J,Booth N.Occupational asthma caused by
latex in a surgical glove manufacturing plant.J allergy Clin Immunol 1990;85:626-31.
29.Beuers U,Bauer X,SchraudolphM,Richter WO.Anaphylactic shock after
a game of squash in atopic women with latex allergy.Lancet 1990;335:1095
30.RodriguesM,Vega F,Garcia M et al.Hypersensitivity to latex,chestnut
,and banana.Ann Allergy 1993;70:31-4.
31.Makinen-Kiljunen,S Banana allergy in patients with immediate
–type hypersensitivity to natural rubber latex :characterization of cross
reacting antibodies and allergens.J Allergy Clin Immunol 1994;93:990-6.
32.Heilman DK,Jones RT,Swanson MC,Yunginger JW.A prospective ,controlled
study showing that rubber gloves are the major contributor to latex aeroallergen
levels in the operating room.J Allergy Clin Immunol 1992;98:325-30.
33.Orfan NA,Reed R,Dykewicz MS,Ganz M,KolskiGB.Occupational asthma
in a latex doll manufacturing plant .J All Clin Immunol 1994;94:826-30
34.Goh CL.Hand dermatitis from a rubber motorcycle handle .Contact
Dermatitis 1987;16:40-41.
35.Ownby DR.Is rubber elongaiton factor the major allergen of latex?J
Allergy Clin Immunol 1993;92:633-5.
36.Czuppon AB,Rennert S ,EngelkeT et al .The rubber elongation factor
of rubber trees(Hevea Brasiliensis)is the major allergen in latex.J Allergy
Clin Immunol 1993;92:690-7
37.Kurup VP,Kumar A,Kelly KJ,et al.Characterizationof monoclonal
antibody against latex protein associated with latex allergy.J Allergy
Clin Immunol 1993;92:638-43.
38.Slater JE,Trybul DE.Affinity purification of latex antigens.J
Allergy Clin Immunol 1994;93:644-9
39.Chen Z,Posch A,Lohaus C et al Isolation and identification of
hevein as a major IgE binding polypeptide in Hevea latex.J All Clin Imm
1997;99:402-9.
40.Conde-SalazarL,del –Rio E,Guimaraens D,Domingo AG.Type I allergy
to rubber additives.A 10 year study of 686 cases.J Am Acad Derm`1993;29:176-80.
41.Vandenplas O,Charous BL,Tarlo S.Chapter 23 Latex allergy in Asthma
in the Workplace.ed I L Bernstein,M Chan –Yeung,JL Malo,DI Bernstein second
edition1999 Marcel Dekker Inc NY,NY:425-44
42.Shield SW,Blaiss MS.Prevalence of latex allergy in children evaluated
for inhalant allergy.Allergy Proc 1992;13:129-31.
43.Charous BL,Hamilton RG,Yunginger JW.Occupational latex exposure
:Characteristics of contact and systemic reactions in 47 workers.J Allergy
Clin Immunol1994;943:12-8
44.Bubak ME,Reed CE ,Fransway AF,Yunginger JW,et al Allergic reactions
to latex among health- care workers.Mayo Clinic Proc.1992;67:1075-9.
45.Arellano R,Bradley J Sussman G.Prevalence of latex sensitization
among hospital physicians occupationally exposed to latex gloves.Anesthesiology.1992;77:905-8.
46.Grzybowski M,Ownby DR,Peyser PA,Johnson CC,Schork MA.The prevalence
of anti-latex IgE antibodies among registered nurses.J Allergy Clin Immunol
1996;98:535-44.
47.Hamann B,Hamann C,Taylor JS.Managing latex allergies in the dental
office.CDA J 1995;23:45-50.
48.Berkey ZT,Luciano WJ,James WD.Latex glove allergy .A survey of
the US Army Dental Corps.JAMA 1992;268 :2695-7
49.Sussman GL ,Beezhold DH.Allergy to latex rubber .Ann Intern
Med 1995;122:43-6.
50.Hamilton RG,Adkinson NF Jr.Natural rubber latex skin testing
reagents :Safety and diagnostic accuracy of nonammoniated latex,ammoniated
latex and latex rubber glove extract.J Allergy Clin Immunol 1996;98:872-8
51.Hamilton RG,Adkinson NF,Jr .Multi-center Latex Skin Testing Study
Task Force .Diagnosis of natural rubber latex allergy :Multicenter latex
skin testing efficacy study.J Allergy Clin Immunol 1998;102:482-90.
52.Yunginger JW.Diagnostic skin testing for natural rubber latex
allergy.J Allergy Clin Immunol 1998;102:351-2.
53.Kelly KJ,Kurup V,Zacharisen M, et al.Skin testing and serologic
testing in the treatment of latex allergy .J Allergy Clin Immunol 1993;91:1140-5.
54.Shah SR,Beezhold D,McGeady SJ.Oral latex desensitization J Allergy
Clin Immunol 1994;93:181.
55.Sockin SM,Young MC.Preoperative prophylaxis of latex anaphylaxis
.J Allergy Clin Immunol 1991;87:269.
56.Slater JE,PauporeE,Zhang Y,Tet al The latex allergen Hev b5 transcript
is widely distributed after subcutaneous injection in BALB/cmice of its
DNA vaccine.J AllClin Imm 1998;102:469-75.
57.Hunt LW ,Boone-Orke JL,Fransway AF ,et al.A medical-center-wide
,multidisciplinary approach to the problem of natural rubber latex
allergy J.Occ Env Med 1996;38:765-70.
58.Hamilton R,Brown,RH. Natural history of latex allergy in
sensitized health-care workers .J All Clin Imunol 1999;103(1)Pt 2:S52 Abstr#197
59.Harrigan EA,Kelly KJ,Elms N,Kurup VP .Latex allergy in children
with Spina bifida :A five year follow up study.J Allergy Clin Immunol 1999;103(1)Pt
2 :S 51Abst #194
*********************************************************************
Dean Handley, PhD, MBA
Active Metabolites for Allergy and Single
Isomers for Asthma
Thursday, March 16, 2000 8:00-9:00 AM
POST-LECTURE QUESTIONS
1. Third Generation Antihistamines are:
a. reformulation of second generation antihistamines
b. prodrugs designed for sustained release
c. active metabolites of second generation compounds
2. The potential or observed advantages of Third Generation Antihistamines
are:
a. reduced cardiotoxicity related to arrhythmias
b. enhanced receptor potency
c. enhanced onset of action
d. all of the above
3. All marketed beta agonists are:
a. racemates
b. single isomers
c. unknown
d. of various forms
4. The use of racemates as therapeutics is:
a. supported by the FDA
b. no longer a favored approach by the FDA
c. unknown by the FDA
d. all of the above
5. The development of single isomer B agonists is:
a. the most recent development in the bronchodilator field
b. consistent with 1992 FDA guidelines
c. able to offer potential improvements in efficacy
d. all of the above
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