by Sea Urchin Genome Sequencing Consortium, Erica Sodergren, George M. Weinstock, Eric H Davidson, R. Andrew Cameron, Richard A. Gibbs, Robert C. Angerer, Lynne M. Angerer, Maria Ina Arnone, David R. Burgess, Robert D. Burke, James A. Coffman, Michael Dean, Maurice R. Elphick, Charles A. Ettensohn, Kathy R. Foltz, Amro Hamdoun, Richard O. Hynes, William H. Klein, William Marzluff, David R. McClay, Robert L. Morris, Arcady Mushegian, Jonathan P. Rast, L. Courtney Smith, Michael C. Thorndyke, Victor D. Vacquier, Gary M. Wessel, Greg Wray, Lan Zhang, Christine G. Elsik, Olga Ermolaeva, Wratko Hlavina, Gretchen Hofmann, Paul Kitts, Melissa J. Landrum, Aaron J. Mackey, Donna Maglott, Georgia Panopoulou, Albert J. Poustka, Kim Pruitt, Victor Sapojnikov, Xingzhi Song, Alexandre Souvorov, Victor Solovyev, Zheng Wei, Charles A. Whittaker, Kim Worley, K. James Durbin, Yufeng Shen, Olivier Fedrigo, David Garfield, Ralph Haygood, Alexander Primus, Rahul Satija, Tonya Severson, Manuel L. Gonzalez-Garay, Andrew R. Jackson, Aleksandar Milosavljevic, Mark Tong, Christopher E. Killian, Brian T. Livingston, Fred H. Wilt, Nikki Adams, Robert Bell??, Seth Carbonneau, Rocky Cheung, Patrick Cormier, Bertrand Cosson, Jenifer Croce, Antonio Fernandez-Guerra, Anne-Marie Genevi??re, Manisha Goel, Hemant Kelkar, Julia Morales, Odile Mulner-Lorillon, Anthony J. Robertson, Jared V. Goldstone, Bryan Cole, David Epel, Bert Gold, Mark E. Hahn, Meredith Howard-Ashby, Mark Scally, John J. Stegeman, Erin L. Allgood, Jonah Cool, Kyle M. Judkins, Shawn S. McCafferty, Ashlan M. Musante, Robert A. Obar, Amanda P. Rawson, Blair J. Rossetti, Ian R. Gibbons, Matthew P. Hoffman, Andrew Leone, Sorin Istrail, Stefan C. Materna, Manoj P. Samanta, Viktor et al. Stolc
Abstract:
We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology. The sequencing strategy combined whole-genome shotgun and bacterial artificial chromosome (BAC) sequences. This use of BAC clones, aided by a pooling strategy, overcame difficulties associated with high heterozygosity of the genome. The genome encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside the deuterostomes. This echinoderm genome provides an evolutionary outgroup for the chordates and yields insights into the evolution of deuterostomes.
Reference:
Sea Urchin Genome Sequencing Consortium, Erica Sodergren, George M. Weinstock, Eric H Davidson, R. Andrew Cameron, Richard A. Gibbs, Robert C. Angerer, Lynne M. Angerer, Maria Ina Arnone, David R. Burgess, Robert D. Burke, James A. Coffman, Michael Dean, Maurice R. Elphick, Charles A. Ettensohn, Kathy R. Foltz, Amro Hamdoun, Richard O. Hynes, William H. Klein, William Marzluff, David R. McClay, Robert L. Morris, Arcady Mushegian, Jonathan P. Rast, L. Courtney Smith, Michael C. Thorndyke, Victor D. Vacquier, Gary M. Wessel, Greg Wray, Lan Zhang, Christine G. Elsik, Olga Ermolaeva, Wratko Hlavina, Gretchen Hofmann, Paul Kitts, Melissa J. Landrum, Aaron J. Mackey, Donna Maglott, Georgia Panopoulou, Albert J. Poustka, Kim Pruitt, Victor Sapojnikov, Xingzhi Song, Alexandre Souvorov, Victor Solovyev, Zheng Wei, Charles A. Whittaker, Kim Worley, K. James Durbin, Yufeng Shen, Olivier Fedrigo, David Garfield, Ralph Haygood, Alexander Primus, Rahul Satija, Tonya Severson, Manuel L. Gonzalez-Garay, Andrew R. Jackson, Aleksandar Milosavljevic, Mark Tong, Christopher E. Killian, Brian T. Livingston, Fred H. Wilt, Nikki Adams, Robert Bell??, Seth Carbonneau, Rocky Cheung, Patrick Cormier, Bertrand Cosson, Jenifer Croce, Antonio Fernandez-Guerra, Anne-Marie Genevi??re, Manisha Goel, Hemant Kelkar, Julia Morales, Odile Mulner-Lorillon, Anthony J. Robertson, Jared V. Goldstone, Bryan Cole, David Epel, Bert Gold, Mark E. Hahn, Meredith Howard-Ashby, Mark Scally, John J. Stegeman, Erin L. Allgood, Jonah Cool, Kyle M. Judkins, Shawn S. McCafferty, Ashlan M. Musante, Robert A. Obar, Amanda P. Rawson, Blair J. Rossetti, Ian R. Gibbons, Matthew P. Hoffman, Andrew Leone, Sorin Istrail, Stefan C. Materna, Manoj P. Samanta, Viktor et al. Stolc, "The Genome of the Sea Urchin Strongylocentrotus purpuratus", In Science, vol. 314, no. 5801, pp. 941-952, 2006.
Bibtex Entry:
@ARTICLE{Consortium2006,
author = {Consortium, Sea Urchin Genome Sequencing and Sodergren, Erica and
Weinstock, George M. and Davidson, Eric H and Cameron, R. Andrew
and Gibbs, Richard A. and Angerer, Robert C. and Angerer, Lynne M.
and Arnone, Maria Ina and Burgess, David R. and Burke, Robert D.
and Coffman, James A. and Dean, Michael and Elphick, Maurice R. and
Ettensohn, Charles A. and Foltz, Kathy R. and Hamdoun, Amro and Hynes,
Richard O. and Klein, William H. and Marzluff, William and McClay,
David R. and Morris, Robert L. and Mushegian, Arcady and Rast, Jonathan
P. and Smith, L. Courtney and Thorndyke, Michael C. and Vacquier,
Victor D. and Wessel, Gary M. and Wray, Greg and Zhang, Lan and Elsik,
Christine G. and Ermolaeva, Olga and Hlavina, Wratko and Hofmann,
Gretchen and Kitts, Paul and Landrum, Melissa J. and Mackey, Aaron
J. and Maglott, Donna and Panopoulou, Georgia and Poustka, Albert
J. and Pruitt, Kim and Sapojnikov, Victor and Song, Xingzhi and Souvorov,
Alexandre and Solovyev, Victor and Wei, Zheng and Whittaker, Charles
A. and Worley, Kim and Durbin, K. James and Shen, Yufeng and Fedrigo,
Olivier and Garfield, David and Haygood, Ralph and Primus, Alexander
and Satija, Rahul and Severson, Tonya and Gonzalez-Garay, Manuel
L. and Jackson, Andrew R. and Milosavljevic, Aleksandar and Tong,
Mark and Killian, Christopher E. and Livingston, Brian T. and Wilt,
Fred H. and Adams, Nikki and Bell??, Robert and Carbonneau, Seth
and Cheung, Rocky and Cormier, Patrick and Cosson, Bertrand and Croce,
Jenifer and Fernandez-Guerra, Antonio and Genevi??re, Anne-Marie
and Goel, Manisha and Kelkar, Hemant and Morales, Julia and Mulner-Lorillon,
Odile and Robertson, Anthony J. and Goldstone, Jared V. and Cole,
Bryan and Epel, David and Gold, Bert and Hahn, Mark E. and Howard-Ashby,
Meredith and Scally, Mark and Stegeman, John J. and Allgood, Erin
L. and Cool, Jonah and Judkins, Kyle M. and McCafferty, Shawn S.
and Musante, Ashlan M. and Obar, Robert A. and Rawson, Amanda P.
and Rossetti, Blair J. and Gibbons, Ian R. and Hoffman, Matthew P.
and Leone, Andrew and Istrail, Sorin and Materna, Stefan C. and Samanta,
Manoj P. and Stolc, Viktor, et al.},
title = {The Genome of the Sea Urchin Strongylocentrotus purpuratus},
journal = {Science},
year = {2006},
volume = {314},
pages = {941--952},
number = {5801},
abstract = {We report the sequence and analysis of the 814-megabase genome of
the sea urchin Strongylocentrotus purpuratus, a model for developmental
and systems biology. The sequencing strategy combined whole-genome
shotgun and bacterial artificial chromosome (BAC) sequences. This
use of BAC clones, aided by a pooling strategy, overcame difficulties
associated with high heterozygosity of the genome. The genome encodes
about 23,300 genes, including many previously thought to be vertebrate
innovations or known only outside the deuterostomes. This echinoderm
genome provides an evolutionary outgroup for the chordates and yields
insights into the evolution of deuterostomes.},
date = {November 10, 2006},
doi = {10.1126/science.1133609},
owner = {Derek},
timestamp = {2012.05.08},
url = {http://www.brown.edu/Research/Istrail_Lab/papers/sci.pdf},
category = {Regulatory Genomics}
}