Determining the causes and consequences of human genetic variation,
using population genetics, statistics, and evolutionary theory

The height distribution of the Ramachandran Lab, September 2018 (celebrating Priya; missing postdoc Kate Brunson).

Sohini gives a State of the Lab chalk talk at our lab retreat in St. George Maine, September 2018.

A meta-selfie outside our current home, Watson CIT at Brown

Dinner during the 2018 lab retreat in St. George Maine.

The Ramachandran Lab graduate students celebrating Priya's wonderful public defense seminar!

Research in the Ramachandran lab addresses problems in population genetics and evolutionary theory, generally using humans as a study system. Our work uses mathematical modeling, applied statistical methods, and computer simulations to make inferences from genetic data. We answer questions like: what loci are under strong adaptive selection in the human genome? are there genetic pathways we can identify that underlie common diseases such as diabetes? does genetic variation account for some ethnic disparities in disease incidence and outcome? what features of human demographic history can we infer from genetic data alone?

Our research and a subset of lab members are currently funded by multiple grants from the National Institutes of Health.