Carotid body paraganglioma

Medium and high magnification microphotos of this carotid body tumor show large polygonal cells with abundant clear  or eosinophilic granular cytoplasm. The cells tend to cluster in nests (zellballen).  See also Female reproductive; cervix.

Clusters of neuroendocrine cells are distributed throughout the neck, thorax, abdomen, and pelvis; they can give rise to tumors called paragangliomas or chemodectomas. These tumors are alse called glomus tumors. Additional sites in the head and neck region for these tumors are the jugular bulb, the middle ear cavity, and the vagus nerve.

From the slide collection of the late Dr. Charles Kuhn