Message from the Chair - Professor Kimberly Mowry

Welcome to the Department of Molecular Biology, Cell Biology & Biochemistry (MCB), which is the largest on-campus department in the Division of Biology and Medicine. We offer a wide range of undergraduate and graduate courses that form the core of modern experimental biology. Our faculty offer training in genetics, biochemistry, developmental biology, cellular biology, molecular biology, genomics, and proteomics. The Department is devoted to cutting-edge research that addresses basic questions in biology, including the control of gene expression, cell fate determination, protein synthesis, the genetics of behavior, control of the cell cycle, and signaling pathways within the cell.

Research in our department employs a range of cross-disciplinary approaches, including state of the art optical tools for confocal and electron microscopy, physical technologies such as X-ray diffraction, and innovative techniques in molecular biology. Core facilities are centralized shared resources that support our research and teaching missions. The Leduc Imaging Facility is dedicated to high-resolution imaging in the life sciences. The facility includes a Transmission Electron Microscope, a Scanning Electron Microscope, two Fluorescence Microscopes, a Fluorescence Stereomicroscope, three Confocal Laser Scanning Microscopes, a Multiphoton Microscope, and software for image analysis. The Genomics Core Facility, located at 70 Ship Street provides state-of-the-art genomics and proteomics equipment and services to researchers at both Brown University and the entire Rhode Island research community and external customers. The facility offers DNA/RNA shearing, sample QC, Affymetrix microarray, qPCR services and provides assistance with experimental design, trouble shooting, and data analysis. The Center for Computational Molecular Biology (CCMB) promotes the development, implementation and application of analytical and computational methods to foundational questions in the biological and medical sciences. The research programs of the Core Faculty in CCMB lie fundamentally at the intersection of computer science, evolutionary biology, mathematics, and molecular and cellular biology. For a full list of the facilities please see (link to website).

The faculty research laboratories in our department are housed in two locations. Sidney Frank Hall of Life Sciences is a five-story, 169,000-square-foot glass and brick structure devoted to the study of human biology and the Laboratory of Molecular Medicine that houses laboratories of faculty drawn from five basic science departments of the Brown Medical School, and two cutting edge research centers. The Center of Computational Molecular Biology and the Center for Genomics and Proteomics.

The Departmental website provides information about our faculty and their research, our graduate program, our course offerings, and the MCB administrative staff.