Eunsuk Kim

Professor of Chemistry

Research Area

Chemical Biology
Inorganic Chemistry

Contact Info

GeoChem 327401-863-3591EmailResearchers@Brown ProfileKim Lab Webpage

Research Statement

The research projects in the Kim lab are in the area of bioinorganic chemistry with a goal of developing fundamental inorganic chemistry to address challenging biological and environmental problems and questions. Toward this goal, our research program will use a multidisciplinary approach, drawing from synthetic inorganic chemistry, spectroscopy, biochemistry, and toxicology.

Areas of Interest

  • Bioinorganic chemistry
  • Coordination chemistry
  • Redox signaling
  • Nitric oxide signaling
  • Energy
  • Carbon dioxide conversion

Education

  • 2004 - Ph.D, Inorganic Chemistry: Johns Hopkins University
  • 1996 - M.S., Chemistry: Korean University, Seoul, Korea
  • 1994 - B.S., Chemistry: Sangmyung University, Seoul, Korea

Selected Publications

  • Speelman, A. L.; Zhang, B.; Silakovi, A.; Skodje, K. M.; Alp, E. E.; Zhao, J.; Hu, M. Y.; Kim, E.; Krebs, C.; Lehnert, N., Unusual Synthetic Pathway for an {Fe(NO)(2)}(9) Dinitrosyl Iron Complex (DNIC) and Insight into DNIC Electronic Structure via Nuclear Resonance Vibrational Spectroscopy. Inorg Chem 2016, 55 (11), 5485-5501.
  • Cao, R.; Elrod, L. T.; Lehane, R. L.; Kim, E.; Karlin, K. D., A Peroxynitrite Dicopper Complex: Formation via Cu-NO and Cu-O-2 Intermediates and Reactivity via O-O Cleavage Chemistry. J Am Chem Soc 2016, 138 (49), 16148-16158.
  • Fitzpatrick, J.; Kim, E., New Synthetic Routes to Iron-Sulfur Clusters: Deciphering the Repair Chemistry of 2Fe-2S Clusters from Mononitrosyl Iron Complexes. Inorg Chem 2015, 54 (22), 10559-10567.
  • Tran, C. T.; Williard, P. G.; Kim, E., Nitric Oxide Reactivity of 2Fe-2S Clusters Leading to H2S Generation. J Am Chem Soc 2014, 136 (34), 11874-11877.
  • Skodje, K. M.; Kwon, M. Y.; Chung, S. W.; Kim, E., Coordination-triggered NO release from a dinitrosyl iron complex leads to anti-inflammatory activity. Chem Sci 2014, 5 (6), 2374-2378.
  • Fitzpatrick, J.; Kalyvas, H.; Filipovic, M. R.; Ivanovic-Burmazovic, I.; MacDonald, J. C.; Shearer, J.; Kim, E., Transformation of a Mononitrosyl Iron Complex to a 2Fe-2S Cluster by a Cysteine Analogue. J Am Chem Soc 2014, 136 (20), 7229-7232.
  • Seo, J.; Williard, P. G.; Kim, E., Deoxygenation of Mono-oxo Bis(dithiolene) Mo and W Complexes by Protonation. Inorg Chem 2013, 52 (15), 8706-8712.
  • Fitzpatrick, J.; Kalyvas, H.; Shearer, J.; Kim, E., Dioxygen mediated conversion of {Fe(NO)(2)}(9) dinitrosyl iron complexes to Roussin's red esters. Chem Commun 2013, 49 (49), 5550-5552.
  • Tran, C. T.; Kim, E., Acid-Dependent Degradation of a 2Fe-2S Cluster by Nitric Oxide. Inorg Chem 2012, 51 (19), 10086-10088.
  • Skodje, K. M.; Williard, P. G.; Kim, E., Conversion of {Fe(NO)(2)}(10) dinitrosyl iron to nitrato iron(III) species by molecular oxygen. Dalton T 2012, 41 (26), 7849-7851.
  • Seo, J.; Kim, E., O-Atom Exchange between H2O and CO2 Mediated by a Bis(dithiolene)tungsten Complex. Inorg Chem 2012, 51 (15), 7951-7953.
  • Nhut, G. T.; Kalyvas, H.; Skodje, K. M.; Hayashi, T.; Moenne-Loccoz, P.; Callan, P. E.; Shearer, J.; Kirschenbaum, L. J.; Kim, E., Phenol Nitration Induced by an {Fe(NO)(2)}(10) Dinitrosyl Iron Complex. J Am Chem Soc 2011, 133 (5), 1184-1187.