- Royce Fellowship
Nicholas
Mroz
Award Year
2017
Phosphoproteomic Analysis of Tyrosine Phosphatases Within T Cell Negative Feedback Networks
Faculty Sponsor: Arthur Salomon
T cells are crucial members of the immune system and typically initiate and orchestrate the clearance of infectious agents; however, inappropriate activation of regulation of T cells can result in various autoimmune diseases. Nick will work to identify the tyrosine phosphatase that mediates a recently discovered negative feedback pathway within the T cell signaling network, which may be important in determining the intensity and efficacy of a T cell’s response to stimuli.