Chromatin Architecture and Remodeling at Start Sites of DNA Replication

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Wednesday, December 14, 2016 4:00pm - 5:00pm
Watson CIT - SWIG Boardroom (CIT241)

"Chromatin architecture and remodeling at start sites of DNA replication"

David MacAlpine
Duke University, Department of Pharmacology and Cancer Biology

David MacAlpine uses genomic approaches to study how the start sites of DNA replication are selected and regulated in the context of the local chromatin environment to maintain genomic stability and to ensure the accurate inheritance of genetic and epigenetic information. In the past two years he has published papers in Cell, Nature, PNAS, Genome Res (2X), EMBO J, Genes Dev (2X), MCB (2X) and NAR.