Brown University School of Engineering

Engineering Seminar: Biomedical Engineering

Thursday, December 6, 2018

9:00am - 10:00am

School of Engineering

Barus and Holley, 190

Tammy Haut Donahue, Dept. Head and Professor of Biomedical Engineering, University of Massachusetts, Amherst, will present a talk: “Post-Traumatic Osteoarthritis: The Role of Menisci and their Ligamentous Attachments”.

Abstract: Most people in the US know someone who has traumatically injured their knee, or they themselves have sustained an injury. Despite surgical intervention following traumatic knee joint injury, these knees still typically develop osteoarthritis. The menisci of the knee are fibrocartilagenous structures that are mechanically sensitive and will respond to changes in mechanical loading with altered biochemical activity. The role of menisci and their ligamentous attachments in the health of the knee joint will be discussed. The development of a novel, closed joint impact injury animal model will be introduced with data to suggest that simple reconstruction of torn tissue is not adequate to prevent knee joint degeneration. Ongoing projects for anterior cruciate ligament and meniscal replacement will be presented.