Publications

Recent Peer-reviewed publications:

Gil, J. A., Chambers, A., Shah, K. N., Crisco, J. J., Got, C., & Akelman, E. (2017). A Biomechanical Evaluation of a 2-Suture Anchor Repair Technique for Thumb Metacarpophalangeal Joint Ulnar Collateral Ligament Injuries. Hand (New York, N.Y.), 1558944717725380. https://doi.org/10.1177/1558944717725380

Perrone, G. S., Proffen, B. L., Kiapour, A. M., Sieker, J. T., Fleming, B. C., & Murray, M. M. (2017). Bench-to-bedside: Bridge-enhanced anterior cruciate ligament repair. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society. https://doi.org/10.1002/jor.23632

Fleming, B. C. (2017). Conflicted. The American Journal of Sports Medicine, 45(8), 1727–1729. https://doi.org/10.1177/0363546517716156

Gil, J. A., Ebert, K., Blanchard, K., Goodman, A. D., Crisco, J. J., & Katarincic, J. A. (2017). Efficacy of a radial-based thumb metacarpophalangeal-stabilizing orthosis for protecting the thumb metacarpophalangeal joint ulnar collateral ligament. Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists. https://doi.org/10.1016/j.jht.2017.06.002

Mansuripur, P. K., Gil, J. A., Cassidy, D., Kane, P., Kluk, A., Crisco, J. J., & Akelman, E. (2017). Fixation Strength in Full and Limited Fixation of Osteoporotic Distal Radius Fractures. Hand (New York, N.Y.), 1558944717708032. https://doi.org/10.1177/1558944717708032

Waller, K. A., Chin, K. E., Jay, G. D., Zhang, L. X., Teeple, E., McAllister, S., Badger, G. J., Schmidt, T. A., & Fleming, B. C. (2017). Intra-articular Recombinant Human Proteoglycan 4 Mitigates Cartilage Damage After Destabilization of the Medial Meniscus in the Yucatan Minipig. The American Journal of Sports Medicine, 45(7), 1512–1521. https://doi.org/10.1177/0363546516686965

Coughlan, M. J., Bourdillon, A., Crisco, J. J., Kenney, D., Weiss, A.-P., & Ladd, A. L. (2017a). Reduction in Cylindrical Grasp Strength Is Associated With Early Thumb Carpometacarpal Osteoarthritis. Clinical Orthopaedics and Related Research, 475(2), 522–528. https://doi.org/10.1007/s11999-016-5151-2

Coughlan, M. J., Bourdillon, A., Crisco, J. J., Kenney, D., Weiss, A.-P., & Ladd, A. L. (2017b). Reduction in Cylindrical Grasp Strength Is Associated With Early Thumb Carpometacarpal Osteoarthritis. Clinical Orthopaedics and Related Research, 475(2), 522–528. https://doi.org/10.1007/s11999-016-5151-2

Larson, K. M., Zhang, L., Elsaid, K. A., Schmidt, T. A., Fleming, B. C., Badger, G. J., & Jay, G. D. (2017). Reduction of friction by recombinant human proteoglycan 4 in IL-1α stimulated bovine cartilage explants. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 35(3), 580–589. https://doi.org/10.1002/jor.23367

Beveridge, J. E., Walsh, E. G., Murray, M. M., & Fleming, B. C. (2017). Sensitivity of ACL volume and T2(∗) relaxation time to magnetic resonance imaging scan conditions. Journal of Biomechanics, 56, 117–121. https://doi.org/10.1016/j.jbiomech.2017.03.010

Sieker, J. T., Proffen, B. L., Waller, K. A., Chin, K. E., Karamchedu, N. P., Akelman, M. R., Perrone, G. S., Kiapour, A. M., Konrad, J., Murray, M. M., & Fleming, B. C. (2017). Transcriptional profiling of articular cartilage in a porcine model of early post-traumatic osteoarthritis. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society. https://doi.org/10.1002/jor.23644

Pidgeon, T. S., Crisco, J. J., Waryasz, G. R., Moore, D. C., & DaSilva, M. F. (2017). Ulnar Styloid Base Fractures Cause Distal Radioulnar Joint Instability in a Cadaveric Model. Hand (New York, N.Y.), 1558944716685830. https://doi.org/10.1177/1558944716685830

Du, G., Zhan, H., Ding, D., Wang, S., Wei, X., Wei, F., Zhang, J., Bilgen, B., Reginato, A. M., Fleming, B. C., Deng, J., & Wei, L. (2016). Abnormal Mechanical Loading Induces Cartilage Degeneration by Accelerating Meniscus Hypertrophy and Mineralization After ACL Injuries In Vivo. The American Journal of Sports Medicine, 44(3), 652–663. https://doi.org/10.1177/0363546515621285

Teeple, E., Karamchedu, N. P., Larson, K. M., Zhang, L., Badger, G. J., Fleming, B. C., & Jay, G. D. (2016). Arthroscopic irrigation of the bovine stifle joint increases cartilage surface friction and decreases superficial zone lubricin. Journal of Biomechanics, 49(13), 3106–3110. https://doi.org/10.1016/j.jbiomech.2016.07.024

Chin, K. E., Karamchedu, N. P., Patel, T. K., Badger, G. J., Akelman, M. R., Moore, D. C., Proffen, B. L., Murray, M. M., & Fleming, B. C. (2016). Comparison of micro-CT post-processing methods for evaluating the trabecular bone volume fraction in a rat ACL-transection model. Journal of Biomechanics, 49(14), 3559–3563. https://doi.org/10.1016/j.jbiomech.2016.08.024

Akelman, M. R., Fadale, P. D., Hulstyn, M. J., Shalvoy, R. M., Garcia, A., Chin, K. E., Duryea, J., Badger, G. J., Tung, G. A., & Fleming, B. C. (2016). Effect of Matching or Overconstraining Knee Laxity During Anterior Cruciate Ligament Reconstruction on Knee Osteoarthritis and Clinical Outcomes: A Randomized Controlled Trial With 84-Month Follow-up. The American Journal of Sports Medicine, 44(7), 1660–1670. https://doi.org/10.1177/0363546516638387

Proffen, B. L., Sieker, J. T., Murray, M. M., Akelman, M. R., Chin, K. E., Perrone, G. S., Patel, T. K., & Fleming, B. C. (2016). Extracellular matrix-blood composite injection reduces post-traumatic osteoarthritis after anterior cruciate ligament injury in the rat. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 34(6), 995–1003. https://doi.org/10.1002/jor.23117

Rainbow, M. J., Wolff, A. L., Crisco, J. J., & Wolfe, S. W. (2016). Functional kinematics of the wrist. The Journal of Hand Surgery, European Volume, 41(1), 7–21. https://doi.org/10.1177/1753193415616939

Wilcox, B. J., Wilkins, M. M., Basseches, B., Schwartz, J. B., Kerman, K., Trask, C., Brideau, H., & Crisco, J. J. (2016). Joint-Specific Play Controller for Upper Extremity Therapy: Feasibility Study in Children With Wrist Impairment. Physical Therapy, 96(11), 1773–1781. https://doi.org/10.2522/ptj.20150493

Christino, M. A., Fleming, B. C., Machan, J. T., & Shalvoy, R. M. (2016). Psychological Factors Associated With Anterior Cruciate Ligament Reconstruction Recovery. Orthopaedic Journal of Sports Medicine, 4(3), 2325967116638341. https://doi.org/10.1177/2325967116638341

Morris, R. C., Hulstyn, M. J., Fleming, B. C., Owens, B. D., & Fadale, P. D. (2016). Return to Play Following Anterior Cruciate Ligament Reconstruction. Clinics in Sports Medicine, 35(4), 655–668. https://doi.org/10.1016/j.csm.2016.05.009

Murray, M. M., Flutie, B. M., Kalish, L. A., Ecklund, K., Fleming, B. C., Proffen, B. L., & Micheli, L. J. (2016). The Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR) Procedure: An Early Feasibility Cohort Study. Orthopaedic Journal of Sports Medicine, 4(11), 2325967116672176. https://doi.org/10.1177/2325967116672176

Got, C., Vopat, B. G., Mansuripur, P. K., Kane, P. M., Weiss, A. P. C., & Crisco, J. J. (2016). The effects of partial carpal fusions on wrist range of motion. The Journal of Hand Surgery, European Volume, 41(5), 479–483. https://doi.org/10.1177/1753193415607827

McQuillan, T. J., Kenney, D., Crisco, J. J., Weiss, A.-P., & Ladd, A. L. (2016). Weaker Functional Pinch Strength Is Associated With Early Thumb Carpometacarpal Osteoarthritis. Clinical Orthopaedics and Related Research, 474(2), 557–561. https://doi.org/10.1007/s11999-015-4599-9

Proffen, B. L., Vavken, P., Haslauer, C. M., Fleming, B. C., Harris, C. E., Machan, J. T., & Murray, M. M. (2015). Addition of autologous mesenchymal stem cells to whole blood for bioenhanced ACL repair has no benefit in the porcine model. The American Journal of Sports Medicine, 43(2), 320–330. https://doi.org/10.1177/0363546514559826

Thomas, N. P., Li, P., Fleming, B. C., Chen, Q., Wei, X., Xiao-Hua, P., Li, G., & Wei, L. (2015). Attenuation of cartilage pathogenesis in post-traumatic osteoarthritis (PTOA) in mice by blocking the stromal derived factor 1 receptor (CXCR4) with the specific inhibitor, AMD3100. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 33(7), 1071–1078. https://doi.org/10.1002/jor.22862

Kiapour, A. M., Fleming, B. C., & Murray, M. M. (2015). Biomechanical outcomes of bridge-enhanced anterior cruciate ligament repair are influenced by sex in a preclinical model. Clinical Orthopaedics and Related Research, 473(8), 2599–2608. https://doi.org/10.1007/s11999-015-4226-9

Wilcox, B. J., Beckwith, J. G., Greenwald, R. M., Raukar, N. P., Chu, J. J., McAllister, T. W., Flashman, L. A., Maerlender, A. C., Duhaime, A.-C., & Crisco, J. J. (2015). Biomechanics of head impacts associated with diagnosed concussion in female collegiate ice hockey players. Journal of Biomechanics, 48(10), 2201–2204. https://doi.org/10.1016/j.jbiomech.2015.04.005

Ladd, A. L., Messana, J. M., Berger, A. J., & Weiss, A.-P. C. (2015). Correlation of Clinical Disease Severity to Radiographic Thumb Osteoarthritis Index. The Journal of Hand Surgery. https://doi.org/10.1016/j.jhsa.2014.11.021

Crisco, J. J., Schwartz, J. B., Wilcox, B., Costa, L., & Kerman, K. (2015). Design and Kinematic Evaluation of a Novel Joint-Specific Play Controller: Application for Wrist and Forearm Therapy. Physical Therapy, 95(7), 1061–1066. https://doi.org/10.2522/ptj.20140344

Halilaj, E., Moore, D. C., Patel, T. K., Ladd, A. L., Weiss, A.-P. C., & Crisco, J. J. (2015). Early osteoarthritis of the trapeziometacarpal joint is not associated with joint instability during typical isometric loading. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 33(11), 1639–1645. https://doi.org/10.1002/jor.22936

Proffen, B. L., Perrone, G. S., Fleming, B. C., Sieker, J. T., Kramer, J., Hawes, M. L., & Murray, M. M. (2015). Effect of low-temperature ethylene oxide and electron beam sterilization on the in vitro and in vivo function of reconstituted extracellular matrix-derived scaffolds. Journal of Biomaterials Applications, 30(4), 435–449. https://doi.org/10.1177/0885328215590967

Proffen, B. L., Perrone, G. S., Fleming, B. C., Sieker, J. T., Kramer, J., Hawes, M. L., Badger, G. J., & Murray, M. M. (2015). Electron beam sterilization does not have a detrimental effect on the ability of extracellular matrix scaffolds to support in vivo ligament healing. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 33(7), 1015–1023. https://doi.org/10.1002/jor.22855

Franck, J. A., Blume, J., Crisco, J. J., & Franck, C. (2015). Extracting Time-Accurate Acceleration Vectors From Nontrivial Accelerometer Arrangements. Journal of Biomechanical Engineering, 137(9). https://doi.org/10.1115/1.4030942

Fleming, B. C., Proffen, B. L., Vavken, P., Shalvoy, M. R., Machan, J. T., & Murray, M. M. (2015). Increased platelet concentration does not improve functional graft healing in bio-enhanced ACL reconstruction. Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA, 23(4), 1161–1170. https://doi.org/10.1007/s00167-014-2932-6

Crisco, J. J., Halilaj, E., Moore, D. C., Patel, T., Weiss, A.-P. C., & Ladd, A. L. (2015). In Vivo kinematics of the trapeziometacarpal joint during thumb extension-flexion and abduction-adduction. The Journal of Hand Surgery, 40(2), 289–296. https://doi.org/10.1016/j.jhsa.2014.10.062

Halilaj, E., Rainbow, M. J., Moore, D. C., Laidlaw, D. H., Weiss, A.-P. C., Ladd, A. L., & Crisco, J. J. (2015). In vivo recruitment patterns in the anterior oblique and dorsoradial ligaments of the first carpometacarpal joint. Journal of Biomechanics, 48(10), 1893–1898. https://doi.org/10.1016/j.jbiomech.2015.04.028

Teeple, E., Aslani, K., Shalvoy, M. R., Medrano, J. E., Zhang, L., Machan, J. T., Fleming, B. C., & Jay, G. D. (2015). Lubricin deficiency in the murine lumbar intervertebral disc results in elevated torsional apparent modulus. Journal of Biomechanics, 48(10), 2210–2213. https://doi.org/10.1016/j.jbiomech.2015.03.029

Hill, A., Waller, K. A., Cui, Y., Allen, J. M., Smits, P., Zhang, L. X., Ayturk, U. M., Hann, S., Lessard, S. G., Zurakowski, D., Warman, M. L., & Jay, G. D. (2015). Lubricin restoration in a mouse model of congenital deficiency. Arthritis & Rheumatology (Hoboken, N.J.). https://doi.org/10.1002/art.39276

Schneider, M. T. Y., Zhang, J., Crisco, J. J., Weiss, A. P. C., Ladd, A. L., Nielsen, P., & Besier, T. (2015). Men and women have similarly shaped carpometacarpal joint bones. Journal of Biomechanics, 48(12), 3420–3426. https://doi.org/10.1016/j.jbiomech.2015.05.031

Jones, M. H., Spindler, K. P., Fleming, B. C., Duryea, J., Obuchowski, N. A., Scaramuzza, E. A., Oksendahl, H. L., Winalski, C. S., Duong, C. L., Huston, L. J., Parker, R. D., Kaeding, C. C., Andrish, J. T., Flanigan, D. C., Dunn, W. R., & Reinke, E. K. (2015). Meniscus treatment and age associated with narrower radiographic joint space width 2-3 years after ACL reconstruction: data from the MOON onsite cohort. Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society, 23(4), 581–588. https://doi.org/10.1016/j.joca.2014.12.018

Biercevicz, A. M., Akelman, M. R., Fadale, P. D., Hulstyn, M. J., Shalvoy, R. M., Badger, G. J., Tung, G. A., Oksendahl, H. L., & Fleming, B. C. (2015). MRI volume and signal intensity of ACL graft predict clinical, functional, and patient-oriented outcome measures after ACL reconstruction. The American Journal of Sports Medicine, 43(3), 693–699. https://doi.org/10.1177/0363546514561435

Halilaj, E., Moore, D. C., Patel, T. K., Laidlaw, D. H., Ladd, A. L., Weiss, A.-P. C., & Crisco, J. J. (2015). Older asymptomatic women exhibit patterns of thumb carpometacarpal joint space narrowing that precede changes associated with early osteoarthritis. Journal of Biomechanics, 48(13), 3634–3640. https://doi.org/10.1016/j.jbiomech.2015.08.010

Kiapour, A. M., Fleming, B. C., Proffen, B. L., & Murray, M. M. (2015). Sex influences the biomechanical outcomes of anterior cruciate ligament reconstruction in a preclinical large animal model. The American Journal of Sports Medicine, 43(7), 1623–1631. https://doi.org/10.1177/0363546515582024

Zhou, Y., Mohan, A., Moore, D. C., Lin, L., Zhou, F. L., Cao, J., Wu, Q., Qin, Y.-X., Reginato, A. M., Ehrlich, M. G., & Yang, W. (2015). SHP2 regulates osteoclastogenesis by promoting preosteoclast fusion. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology, 29(5), 1635–1645. https://doi.org/10.1096/fj.14-260844

Rainbow, M. J., Kamal, R. N., Moore, D. C., Akelman, E., Wolfe, S. W., & Crisco, J. J. (2015). Subject-Specific Carpal Ligament Elongation in Extreme Positions, Grip, and the Dart Thrower’s Motion. Journal of Biomechanical Engineering, 137(11), 111006. https://doi.org/10.1115/1.4031580

Biercevicz, A. M., Proffen, B. L., Murray, M. M., Walsh, E. G., & Fleming, B. C. (2015). T2 * relaxometry and volume predict semi-quantitative histological scoring of an ACL bridge-enhanced primary repair in a porcine model. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 33(8), 1180–1187. https://doi.org/10.1002/jor.22874

Crisco, J. J., Patel, T., Halilaj, E., & Moore, D. C. (2015). The Envelope of Physiological Motion of the First Carpometacarpal Joint. Journal of Biomechanical Engineering, 137(10), 101002–1 to 101002–8. https://doi.org/10.1115/1.4031117

Biercevicz, A. M., Akelman, M. R., Rubin, L. E., Walsh, E. G., Merck, D., & Fleming, B. C. (2015). The uncertainty of predicting intact anterior cruciate ligament degeneration in terms of structural properties using T(2)(*) relaxometry in a human cadaveric model. Journal of Biomechanics, 48(6), 1188–1192. https://doi.org/10.1016/j.jbiomech.2015.02.021

Kiapour, A. M., Shalvoy, M. R., Murray, M. M., & Fleming, B. C. (2015). Validation of porcine knee as a sex-specific model to study human anterior cruciate ligament disorders. Clinical Orthopaedics and Related Research, 473(2), 639–650. https://doi.org/10.1007/s11999-014-3974-2

Crisco, J. J., Schwartz, J. B., Wilcox, B., Brideau, H., Basseches, B., & Kerman, K. (2015). Wrist range of motion and motion frequency during toy and game play with a joint-specific controller specially designed to provide neuromuscular therapy: A proof of concept study in typically developing children. Journal of Biomechanics, 48(11), 2844–2848. https://doi.org/10.1016/j.jbiomech.2015.04.018

Morse, J. D., Franck, J. A., Wilcox, B. J., Crisco, J. J., & Franck, C. (2014). An experimental and numerical investigation of head dynamics due to stick impacts in girls’ lacrosse. Annals of Biomedical Engineering. https://doi.org/10.1007/s10439-014-1091-8

Crisco, J. J., Rainbow, M. J., Schwartz, J. B., & Wilcox, B. J. (2014). Batting cage performance of wood and nonwood youth baseball bats. Journal of Applied Biomechanics, 30(2), 237–243. https://doi.org/10.1123/jab.2012-0178

Rowson, S., Duma, S. M., Greenwald, R. M., Beckwith, J. G., Chu, J. J., Guskiewicz, K. M., Mihalik, J. P., Crisco, J. J., Wilcox, B. J., McAllister, T. W., Maerlender, A. C., Broglio, S. P., Schnebel, B., Anderson, S., & Brolinson, P. G. (2014). Can helmet design reduce the risk of concussion in football? Journal of Neurosurgery, 120(4), 919–922. https://doi.org/10.3171/2014.1.JNS13916

Zhou, J., Chen, Q., Lanske, B., Fleming, B. C., Terek, R., Wei, X., Zhang, G., Wang, S., Li, K., & Wei, L. (2014). Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice. Arthritis Research & Therapy, 16(1), R11. https://doi.org/10.1186/ar4437

Wilcox, B. J., Machan, J. T., Beckwith, J. G., Greenwald, R. M., Burmeister, E., & Crisco, J. J. (2014). Head-Impact Mechanisms in Men’s and Women’s Collegiate Ice Hockey. Journal of Athletic Training. https://doi.org/10.4085/1062-6050-49.3.19

Halilaj, E., Laidlaw, D. H., Moore, D. C., & Crisco, J. J. (2014a). How Do Sex, Age, and Osteoarthritis Affect Cartilage Thickness at the Thumb Carpometacarpal Joint? Insights from Subject-Specific Cartilage Modeling. In J. M. R. S. Tavares, X. Luo, & S. Li (Eds.), Bio-Imaging and Visualization for Patient-Customized Simulations (pp. 103–111). Springer International Publishing.

Wang, S., Wei, X., Zhou, J., Zhang, J., Li, K., Chen, Q., Terek, R., Fleming, B. C., Goldring, M. B., Ehrlich, M. G., Zhang, G., & Wei, L. (2014). Identification of α2-macroglobulin as a master inhibitor of cartilage-degrading factors that attenuates the progression of posttraumatic osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.), 66(7), 1843–1853. https://doi.org/10.1002/art.38576

Biercevicz, A. M., Walsh, E. G., Murray, M. M., Akelman, M. R., & Fleming, B. C. (2014). Improving the clinical efficiency of T2(⁎) mapping of ligament integrity. Journal of Biomechanics, 47, 2522–2525. https://doi.org/10.1016/j.jbiomech.2014.03.037

Zhang, C., Wei, X., Chen, C., Cao, K., Li, Y., Jiao, Q., Ding, J., Zhou, J., Fleming, B. C., Chen, Q., Shang, X., & Wei, L. (2014). Indian hedgehog in synovial fluid is a novel marker for early cartilage lesions in human knee joint. International Journal of Molecular Sciences, 15(5), 7250–7265. https://doi.org/10.3390/ijms15057250

Halilaj, E., Rainbow, M. J., Got, C., Schwartz, J. B., Moore, D. C., Weiss, A.-P. C., Ladd, A. L., & Crisco, J. J. (2014). In vivo kinematics of the thumb carpometacarpal joint during three isometric functional tasks. Clinical Orthopaedics and Related Research, 472(4), 1114–1122. https://doi.org/10.1007/s11999-013-3063-y

Yang, X., Trehan, S. K., Guan, Y., Sun, C., Moore, D. C., Jayasuriya, C. T., & Chen, Q. (2014). Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. The Journal of Biological Chemistry, 289(50), 34768–34779. https://doi.org/10.1074/jbc.M114.583104

Halilaj, E., Laidlaw, D. H., Moore, D. C., & Crisco, J. J. (2014b). Polar histograms of curvature for quantifying skeletal joint shape and congruence. Journal of Biomechanical Engineering, 136(9), 094503. https://doi.org/10.1115/1.4027938

Crisco, J. J., Costa, L., Rich, R., Schwartz, J., & Wilcox, B. (2014). Surrogate Headform Accelerations Associated with Stick Checks in Girls’ Lacrosse. Journal of Applied Biomechanics. https://doi.org/10.1123/jab.2014-0102

Biercevicz, A. M., Murray, M. M., Walsh, E. G., Miranda, D. L., Machan, J. T., & Fleming, B. C. (2014). T2 * MR relaxometry and ligament volume are associated with the structural properties of the healing ACL. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 32(4), 485–618. https://doi.org/10.1002/jor.22563

Ladd, A. L., Crisco, J. J., Hagert, E., Rose, J., & Weiss, A.-P. C. (2014). The 2014 ABJS Nicolas Andry Award: The Puzzle of the Thumb: Mobility, Stability, and Demands in Opposition. Clinical Orthopaedics and Related Research, 472(12), 3605–3622. https://doi.org/10.1007/s11999-014-3901-6

Jay, G. D., & Waller, K. A. (2014). The biology of lubricin: near frictionless joint motion. Matrix Biology: Journal of the International Society for Matrix Biology, 39, 17–24. https://doi.org/10.1016/j.matbio.2014.08.008

Rogg, J., Spader, H., Wilcox, B. J., Ellermeier, A., Correira, S., Chodobski, A., Szmydynger-Chodobska, J., Raukar, N., Machan, J. T., Crisco, J. J., LaFrance, W. C., Crisco, J. J., & Brown University Traumatic Brain Injury Research Consortium. (2014). The Brown University traumatic Brain Injury Research Consortium and the Norman Prince Neurosciences Institute. Rhode Island Medical Journal (2013), 97(5), 22–26.

Halilaj, E., Moore, D. C., Laidlaw, D. H., Got, C. J., Weiss, A.-P. C., Ladd, A. L., & Crisco, J. J. (2014). The morphology of the thumb carpometacarpal joint does not differ between men and women, but changes with aging and early osteoarthritis. Journal of Biomechanics, 47(11), 2709–2714. https://doi.org/10.1016/j.jbiomech.2014.05.005

Halilaj, E., Moore, D. C., Patel, T. K., Laidlaw, D. H., Ladd, A. L., Weiss, A.-P. C., & Crisco, J. J. (2014). Thumb carpometacarpal joint congruence during functional tasks and thumb range-of-motion activities. Conference Proceedings: ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2014, 4354–4357. https://doi.org/10.1109/EMBC.2014.6944588

Fleming, B. C. (2014). Time Zero. The American Journal of Sports Medicine, 42(7), 1531–1533. https://doi.org/10.1177/0363546514539637

Buffi, J. H., Crisco, J. J., & Murray, W. M. (2013). A method for defining carpometacarpal joint kinematics from three-dimensional rotations of the metacarpal bones captured in vivo using computed tomography. Journal of Biomechanics, 46(12), 2104–2108. https://doi.org/10.1016/j.jbiomech.2013.05.019

Teeple, E., Jay, G. D., Elsaid, K. A., & Fleming, B. C. (2013). Animal models of osteoarthritis: challenges of model selection and analysis. The AAPS Journal, 15(2), 438–446. https://doi.org/10.1208/s12248-013-9454-x

Halilaj, E., Rainbow, M. J., Got, C. J., Moore, D. C., & Crisco, J. J. (2013). A thumb carpometacarpal joint coordinate system based on articular surface geometry. Journal of Biomechanics. https://doi.org/10.1016/j.jbiomech.2012.12.002

Rainbow, M. J., Miranda, D. L., Cheung, R. T. H., Schwartz, J. B., Crisco, J. J., Davis, I. S., & Fleming, B. C. (2013). Automatic determination of an anatomical coordinate system for a three-dimensional model of the human patella. Journal of Biomechanics, 46(12), 2093–2096. https://doi.org/10.1016/j.jbiomech.2013.05.024

Fleming, B.C. (2013). Bio-enhancement of ACL graft healing. In The ACL Handbook: Knee Biology, Mechanics, and Treatment (pp. 285–299). New York: Springer.

Murray, M. M., & Fleming, B. C. (2013). Biology of anterior cruciate ligament injury and repair: Kappa delta ann doner vaughn award paper 2013. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 31(10), 1501–1506. https://doi.org/10.1002/jor.22420

Daniels, A. H., Paller, D. J., Koruprolu, S., Palumbo, M. A., & Crisco, J. J. (2013). Dynamic biomechanical examination of the lumbar spine with implanted total spinal segment replacement (TSSR) utilizing a pendulum testing system. PloS One, 8(2), e57412. https://doi.org/10.1371/journal.pone.0057412

Coats-Thomas, M. S., Miranda, D. L., Badger, G. J., & Fleming, B. C. (2013). Effects of ACL reconstruction surgery on muscle activity of the lower limb during a jump-cut maneuver in males and females. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 31(12), 1890–1896. https://doi.org/10.1002/jor.22470

Vavken, P., Proffen, B., Peterson, C., Fleming, B. C., Machan, J. T., & Murray, M. M. (2013). Effects of suture choice on biomechanics and physeal status after bioenhanced anterior cruciate ligament repair in skeletally immature patients: a large-animal study. Arthroscopy: The Journal of Arthroscopic & Related Surgery: Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 29(1), 122–132. https://doi.org/10.1016/j.arthro.2012.07.006

Wilcox, B. J., Beckwith, J. G., Greenwald, R. M., Chu, J. J., McAllister, T. W., Flashman, L. A., Maerlender, A. C., Duhaime, A.-C., & Crisco, J. J. (2013). Head Impact Exposure in Male and Female Collegiate Ice Hockey Players. Journal of Biomechanics. https://doi.org/10.1016/j.jbiomech.2013.10.004

Beckwith, J. G., Greenwald, R. M., Chu, J. J., Crisco, J. J., Rowson, S., Duma, S. M., Broglio, S. P., McAllister, T. W., Guskiewicz, K. M., Mihalik, J. P., Anderson, S., Schnebel, B., Brolinson, P. G., & Collins, M. W. (2013a). Head Impact Exposure Sustained by Football Players on Days of Diagnosed Concussion. Medicine and Science in Sports and Exercise, 45(4), 737–746. https://doi.org/10.1249/MSS.0b013e3182792ed7

Proffen, B. L., Fleming, B. C., & Murray, M. M. (2013). Histologic predictors of maximum failure loads differ between the healing ACL and ACL grafts after 6 and 12 months in vivo. Orthopaedic Journal of Sports Medicine, 1(6). https://doi.org/10.1177/2325967113512457

Biercevicz, A. M., Miranda, D. L., Machan, J. T., Murray, M. M., & Fleming, B. C. (2013). In Situ, noninvasive, T2*-weighted MRI-derived parameters predict ex vivo structural properties of an anterior cruciate ligament reconstruction or bioenhanced primary repair in a porcine model. The American Journal of Sports Medicine, 41(3), 560–566. https://doi.org/10.1177/0363546512472978

Vavken, P., & Fleming, B.C. (2013). In vitro models of ACL injury. In The ACL Handbook: Knee Biology, Mechanics, and Treatment (pp. 123–137). New York: Springer.

Rainbow, M. J., Kamal, R. N., Leventhal, E., Akelman, E., Moore, D. C., Wolfe, S. W., & Crisco, J. J. (2013). In vivo kinematics of the scaphoid, lunate, capitate, and third metacarpal in extreme wrist flexion and extension. The Journal of Hand Surgery, 38(2), 278–288. https://doi.org/10.1016/j.jhsa.2012.10.035

Miranda, D. L., Rainbow, M. J., Crisco, J. J., & Fleming, B. C. (2013). Kinematic differences between optical motion capture and biplanar videoradiography during a jump-cut maneuver. Journal of Biomechanics, 46(3), 567–573. https://doi.org/10.1016/j.jbiomech.2012.09.023

Miranda, D. L., Fadale, P. D., Hulstyn, M. J., Shalvoy, R. M., Machan, J. T., & Fleming, B. C. (2013). Knee biomechanics during a jump-cut maneuver: effects of sex and ACL surgery. Medicine and Science in Sports and Exercise, 45(5), 942–951. https://doi.org/10.1249/MSS.0b013e31827bf0e4

Tompkins, M., Paller, D. J., Moore, D. C., Crisco, J. J., & Terek, R. M. (2013). Locking buttons increase fatigue life of locking plates in a segmental bone defect model. Clinical Orthopaedics and Related Research, 471(3), 1039–1044. https://doi.org/10.1007/s11999-012-2664-1

Haslauer, C. M., Elsaid, K. A., Fleming, B. C., Proffen, B. L., Johnson, V. M., & Murray, M. M. (2013). Loss of Extracellular Matrix from Articular Cartilage is Mediated by the Synovium and Ligament after Anterior Cruciate Ligament Injury. Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society. https://doi.org/10.1016/j.joca.2013.09.003

Vavken, P., Murray, M.M., & Fleming, B.C. (2013). Outcome assessment for ACL tissue Engineering. In The ACL Handbook: Knee Biology, Mechanics, and Treatment (pp. 179–200). New York: Springer.

Akelman, M. R., Teeple, E., Machan, J. T., Crisco, J. J., Jay, G. D., & Fleming, B. C. (2013). Pendulum mass affects the measurement of articular friction coefficient. Journal of Biomechanics, 46(3), 615–618. https://doi.org/10.1016/j.jbiomech.2012.09.034

Yang, W., Wang, J., Moore, D. C., Liang, H., Dooner, M., Wu, Q., Terek, R., Chen, Q., Ehrlich, M. G., Quesenberry, P. J., & Neel, B. G. (2013). Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling. Nature, 499(7459), 491–495. https://doi.org/10.1038/nature12396

Waller, K. A., Zhang, L. X., Elsaid, K. A., Fleming, B. C., Warman, M. L., & Jay, G. D. (2013). Role of lubricin and boundary lubrication in the prevention of chondrocyte apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 110(15), 5852–5857. https://doi.org/10.1073/pnas.1219289110

Murray, M.M., & Fleming, B.C. (2013). The biology of the normal ACL. In The ACL Handbook: Knee Biology, Mechanics, and Treatment (pp. 63–72). New York: Springer.

Fleming, B. C., Fadale, P. D., Hulstyn, M. J., Shalvoy, R. M., Oksendahl, H. L., Badger, G. J., & Tung, G. A. (2013). The effect of initial graft tension after anterior cruciate ligament reconstruction: a randomized clinical trial with 36-month follow-up. The American Journal of Sports Medicine, 41(1), 25–34. https://doi.org/10.1177/0363546512464200

Ladd, A. L., Weiss, A.-P. C., Crisco, J. J., Hagert, E., Wolf, J. M., Glickel, S. Z., & Yao, J. (2013). The thumb carpometacarpal joint: anatomy, hormones, and biomechanics. Instructional Course Lectures, 62, 165–179.

Beckwith, J. G., Greenwald, R. M., Chu, J. J., Crisco, J. J., Rowson, S., Duma, S. M., Broglio, S. P., McAllister, T. W., Guskiewicz, K. M., Mihalik, J. P., Anderson, S., Schnebel, B., Brolinson, P. G., & Collins, M. W. (2013b). Timing of Concussion Diagnosis Is Related to Head Impact Exposure Prior to Injury. Medicine and Science in Sports and Exercise, 45(4), 747–754. https://doi.org/10.1249/MSS.0b013e3182793067

Murray, M. M., & Fleming, B. C. (2013). Use of a bioactive scaffold to stimulate anterior cruciate ligament healing also minimizes posttraumatic osteoarthritis after surgery. The American Journal of Sports Medicine, 41(8), 1762–1770. https://doi.org/10.1177/0363546513483446

Proffen, B. L., McElfresh, M., Fleming, B. C., & Murray, M. M. (2012). A comparative anatomical study of the human knee and six animal species. The Knee, 19(4), 493–499. https://doi.org/10.1016/j.knee.2011.07.005

Wei, F., Zhou, J., Wei, X., Zhang, J., Fleming, B. C., Terek, R., Pei, M., Chen, Q., Liu, T., & Wei, L. (2012). Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage. Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society, 20(7), 755–763. https://doi.org/10.1016/j.joca.2012.03.010

Greenwald, R. M., Chu, J. J., Beckwith, J. G., & Crisco, J. J. (2012). A proposed method to reduce underreporting of brain injury in sports. Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine, 22(2), 83–85. https://doi.org/10.1097/JSM.0b013e31824cc5d3

Got, C., Shuck, J., Biercevicz, A., Paller, D., Mulcahey, M., Zimmermann, M., Blaine, T., & Green, A. (2012). Biomechanical comparison of parallel versus 90-90 plating of bicolumn distal humerus fractures with intra-articular comminution. The Journal of Hand Surgery, 37(12), 2512–2518. https://doi.org/10.1016/j.jhsa.2012.08.042

Vavken, P., Fleming, B. C., Mastrangelo, A. N., Machan, J. T., & Murray, M. M. (2012). Biomechanical outcomes after bioenhanced anterior cruciate ligament repair and anterior cruciate ligament reconstruction are equal in a porcine model. Arthroscopy: The Journal of Arthroscopic & Related Surgery: Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association, 28(5), 672–680. https://doi.org/10.1016/j.arthro.2011.10.008

Drewniak, E. I., Jay, G. D., Fleming, B. C., Zhang, L., Warman, M. L., & Crisco, J. J. (2012). Cyclic loading increases friction and changes cartilage surface integrity in lubricin-mutant mouse knees. Arthritis and Rheumatism, 64(2), 465–473. https://doi.org/10.1002/art.33337

Daniels, A. H., Paller, D. J., Koruprolu, S., McDonnell, M., Palumbo, M. A., & Crisco, J. J. (2012). Dynamic biomechanical examination of the lumbar spine with implanted total disc replacement using a pendulum testing system. Spine, 37(23), E1438–1443. https://doi.org/10.1097/BRS.0b013e31826b39d7

Mulcahey, M. K., Monchik, K. O., Yongpravat, C., Badger, G. J., Fadale, P. D., Hulstyn, M. J., & Fleming, B. C. (2012). Effects of single-bundle and double-bundle ACL reconstruction on tibiofemoral compressive stresses and joint kinematics during simulated squatting. The Knee, 19(4), 469–476. https://doi.org/10.1016/j.knee.2011.05.004

Rainbow, M. J., Crisco, J. J., Moore, D. C., Kamal, R. N., Laidlaw, D. H., Akelman, E., & Wolfe, S. W. (2012). Elongation of the Dorsal Carpal Ligaments: A Computational Study of In Vivo Carpal Kinematics. The Journal of Hand Surgery. https://doi.org/10.1016/j.jhsa.2012.04.025

Daniels, A. H., Paller, D. J., Feller, R. J., Thakur, N. A., Biercevicz, A. M., Palumbo, M. A., Crisco, J. J., & Madom, I. A. (2012). Examination of cervical spine kinematics in complex, multiplanar motions after anterior cervical discectomy and fusion and total disc replacement. The International Journal of Spine Surgery, 6(1), 190–194. https://doi.org/10.1016/j.ijsp.2012.07.002

Brunner, A. M., Henn, C. M., Drewniak, E. I., Lesieur-Brooks, A., Machan, J., Crisco, J. J., & Ehrlich, M. G. (2012). High dietary fat and the development of osteoarthritis in a rabbit model. Osteoarthritis and Cartilage, 20(6), 584–592. https://doi.org/10.1016/j.joca.2012.02.007

Kamal, R. N., Rainbow, M. J., Akelman, E., & Crisco, J. J. (2012). In vivo triquetrum-hamate kinematics through a simulated hammering task wrist motion. The Journal of Bone and Joint Surgery. American Volume, 94(12), e851–857. https://doi.org/10.2106/JBJS.J.01644

Crisco, J. J., Wilcox, B. J., Machan, J. T., McAllister, T. W., Duhaime, A.-C., Duma, S. M., Rowson, S., Beckwith, J. G., Chu, J. J., & Greenwald, R. M. (2012). Magnitude of head impact exposures in individual collegiate football players. Journal of Applied Biomechanics, 28(2), 174–183.

Vance, M. C., Packer, G., Tan, D., Crisco, J. J. T., & Wolfe, S. W. (2012). Midcarpal hemiarthroplasty for wrist arthritis: rationale and early results. Journal of Wrist Surgery, 1(1), 61–68. https://doi.org/10.1055/s-0032-1323644

Waller, K. A., Zhang, L. X., Fleming, B. C., & Jay, G. D. (2012). Preventing friction-induced chondrocyte apoptosis: comparison of human synovial fluid and hylan G-F 20. The Journal of Rheumatology, 39(7), 1473–1480. https://doi.org/10.3899/jrheum.111427

Jay, G. D., Elsaid, K. A., Kelly, K. A., Anderson, S. C., Zhang, L., Teeple, E., Waller, K., & Fleming, B. C. (2012). Prevention of cartilage degeneration and gait asymmetry by lubricin tribosupplementation in the rat following anterior cruciate ligament transection. Arthritis and Rheumatism, 64(4), 1162–1171. https://doi.org/10.1002/art.33461

Rowson, S., Duma, S. M., Beckwith, J. G., Chu, J. J., Greenwald, R. M., Crisco, J. J., Brolinson, P. G., Duhaime, A.-C., McAllister, T. W., & Maerlender, A. C. (2012). Rotational head kinematics in football impacts: an injury risk function for concussion. Annals of Biomedical Engineering, 40(1), 1–13. https://doi.org/10.1007/s10439-011-0392-4

Elsaid, K. A., Zhang, L., Waller, K., Tofte, J., Teeple, E., Fleming, B. C., & Jay, G. D. (2012). The impact of forced joint exercise on lubricin biosynthesis from articular cartilage following ACL transection and intra-articular lubricin’s effect in exercised joints following ACL transection. Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society, 20(8), 940–948. https://doi.org/10.1016/j.joca.2012.04.021

Beynnon, B. D., Johnson, R. J., Naud, S., Fleming, B. C., Abate, J. A., Brattbakk, B., & Nichols, C. E. (2011). Accelerated versus nonaccelerated rehabilitation after anterior cruciate ligament reconstruction: a prospective, randomized, double-blind investigation evaluating knee joint laxity using roentgen stereophotogrammetric analysis. The American Journal of Sports Medicine, 39(12), 2536–2548. https://doi.org/10.1177/0363546511422349

Hoffman, E., Paller, D., Koruprolu, S., Drakos, M., Behrens, S. B., Crisco, J. J., & DiGiovanni, C. W. (2011). Accuracy of plain radiographs versus 3D analysis of ankle stress test. Foot & Ankle International / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society, 32(10), 994–999.

Tompkins, M., Monchik, K. O., Plante, M. J., Fleming, B. C., & Fadale, P. D. (2011). Contact area and pressure in suture bridge rotator cuff repair using knotless lateral anchors. Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA, 19(10), 1788–1793. https://doi.org/10.1007/s00167-011-1478-0

Fujiya, H., Kousa, P., Fleming, B. C., Churchill, D. L., & Beynnon, B. D. (2011). Effect of muscle loads and torque applied to the tibia on the strain behavior of the anterior cruciate ligament: an in vitro investigation. Clinical Biomechanics (Bristol, Avon), 26(10), 1005–1011. https://doi.org/10.1016/j.clinbiomech.2011.06.006

Herfat, S. T., Shearn, J. T., Bailey, D. L., Greiwe, R. M., Galloway, M. T., Gooch, C., & Butler, D. L. (2011). Effect of surgery to implant motion and force sensors on vertical ground reaction forces in the ovine model. Journal of Biomechanical Engineering, 133(2), 021010. https://doi.org/10.1115/1.4003322

Teeple, E., Elsaid, K. A., Jay, G. D., Zhang, L., Badger, G. J., Akelman, M., Bliss, T. F., & Fleming, B. C. (2011). Effects of supplemental intra-articular lubricin and hyaluronic acid on the progression of posttraumatic arthritis in the anterior cruciate ligament-deficient rat knee. The American Journal of Sports Medicine, 39(1), 164–172. https://doi.org/10.1177/0363546510378088

Crisco, J. J., Wilcox, B. J., Beckwith, J. G., Chu, J. J., Duhaime, A.-C., Rowson, S., Duma, S. M., Maerlender, A. C., McAllister, T. W., & Greenwald, R. M. (2011). Head impact exposure in collegiate football players. Journal of Biomechanics, 44(15), 2673–2678. https://doi.org/10.1016/j.jbiomech.2011.08.003

Broglio, S. P., Swartz, E. E., Crisco, J. J., & Cantu, R. C. (2011). In vivo biomechanical measurements of a football player’s C6 spine fracture. The New England Journal of Medicine, 365(3), 279–281. https://doi.org/10.1056/NEJMc1102689

Crisco, J. J., & Greenwald, R. M. (2011). Let’s get the head further out of the game: a proposal for reducing brain injuries in helmeted contact sports. Current Sports Medicine Reports, 10(1), 7–9. https://doi.org/10.1249/JSR.0b013e318205e063

Mastrangelo, A. N., Vavken, P., Fleming, B. C., Harrison, S. L., & Murray, M. M. (2011). Reduced platelet concentration does not harm PRP effectiveness for ACL repair in a porcine in vivo model. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 29(7), 1002–1007. https://doi.org/10.1002/jor.21375

Miranda, D. L., Schwartz, J. B., Loomis, A. C., Brainerd, E. L., Fleming, B. C., & Crisco, J. J. (2011). Static and dynamic error of a biplanar videoradiography system using marker-based and markerless tracking techniques. Journal of Biomechanical Engineering, 133(12), 121002. https://doi.org/10.1115/1.4005471

Crisco, J. J., Heard, W. M. R., Rich, R. R., Paller, D. J., & Wolfe, S. W. (2011). The mechanical axes of the wrist are oriented obliquely to the anatomical axes. The Journal of Bone and Joint Surgery. American Volume, 93(2), 169–177. https://doi.org/10.2106/JBJS.I.01222

Tompkins, M., Plante, M., Monchik, K., Fleming, B., & Fadale, P. (2011). The use of a non-benzodiazepine hypnotic sleep-aid (Zolpidem) in patients undergoing ACL reconstruction: a randomized controlled clinical trial. Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA, 19(5), 787–791. https://doi.org/10.1007/s00167-010-1368-x

Fleming, B. C., Vajapeyam, S., Connolly, S. A., Magarian, E. M., & Murray, M. M. (2011). The use of magnetic resonance imaging to predict ACL graft structural properties. Journal of Biomechanics, 44(16), 2843–2846. https://doi.org/10.1016/j.jbiomech.2011.09.004

Vavken, P., Saad, F. A., Fleming, B. C., & Murray, M. M. (2011). VEGF receptor mRNA expression by ACL fibroblasts is associated with functional healing of the ACL. Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA, 19(10), 1675–1682. https://doi.org/10.1007/s00167-011-1443-y

Fleming, B. C., Magarian, E. M., Harrison, S. L., Paller, D. J., & Murray, M. M. (2010). Collagen scaffold supplementation does not improve the functional properties of the repaired anterior cruciate ligament. Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society, 28(6), 703–709. https://doi.org/10.1002/jor.21071