Welcome to the Department of MMI

The Department of Molecular Microbiology and Immunology's (MMI) mission is to maintain active and integrated research programs that study the interactions between microbes and their hosts. The goal is to understand how these influence the outcome of infection and disease progression. Current research interests in the department include understanding host signaling in response to viral infection, molecular mechanisms of NK and NK T cell activation, and molecular principles underlying fungal pathogenesis. This work provides an interdisciplinary structure for our training programs.

MMI supports undergraduate, graduate, and postdoctoral education in the areas of microbiology and immunology. Departmental instruction includes lecture courses, seminar courses, and laboratory research (both undergraduate independent study and graduate thesis). We foster collaborative studies within the department as well as with faculty in other departments, both on campus and hospital-based.

MMI News
Recent graduate's research honored as best in category for U.S. and Canada 
With the top research paper among North American undergraduates in his discipline, Brown University Class of 2016 graduate Alexander Blum earned honors as the 2016 United States/Canada regional winner of the prestigious Undergraduate Awards in the category of earth and environmental sciences.



New Graduate School dean to address incoming students at Convocation 

On Tuesday, Sept. 6, more than 2,500 new undergraduate, graduate and medical students will process through the famed Van Wickle Gates en route to the College Green for Brown’s 253rd Opening Convocation ceremony. Along with President Christina Paxson and faculty and staff from across the University, there to greet the newest students on College Hill will be keynote speaker Andrew G. Campbell, a longtime professor of medical science who began a new role as dean of the Graduate School on July 1.

A unified approach towards Trypanosoma brucei functional genomics using Gibson assembly
Trypanosoma brucei is the causative agent of human African trypanosomiasis and nagana in cattle. Recent advances in high throughput phenotypic and interaction screens have identified a wealth of novel candidate proteins for diverse functions such as drug resistance, life cycle progression, and cytoskeletal biogenesis. The de Graffenried lab has adapted Gibson assembly, a one-step isothermal process that rapidly assembles multiple DNA segments in a single reaction, to create the plasmids that are essential for establishing the localization and function of proteins in T. brucei. The generality of the Gibson approach allows for rapid assessment of protein function, which is essential for identifying potential drug targets.


Health Check: Computational Biology
New research at Brown University could unlock the secret to a long, healthier life -- or a way to prevent a serious pregnancy complication.The research is bringing together what's going on in the lab with computer technology. It's called computational biology.


NIH awards Brown $11.5M for computational biology research
Brown University will launch a Center for Biomedical Research Excellence in Computational Biology of Human Disease to expand its research using sophisticated computer analyses to understand and fight human diseases.


Be Our Guest
How can we provide a good home for our microbiomes, so they’ll keep us healthy?

 



 

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