The National Science Foundation has awarded Dr. Nicolas Fawzi with an Early Career Development (CAREER) award, the NSF's most prestigious award in support of early-career faculty nationwide. Dr. Fawzi will receive five year of support for his research efforts as well as teaching and outreach activities. The award is aimed at creating a foundation for career-long contributions to reserch and teaching.
Nicolas Fawzi, Molecular Pharmacology, Physiology and Biotechnology
Fawzi’s award will support his work studying the interactions of disordered proteins within cellular assemblies. While most well-studied proteins have a defined structure, many biologically important proteins have unstructured or disordered regions. These proteins are challenging to investigate using traditional methods but are critical for forming membrane-less organelles such as those involved in RNA transcription and processing. Fawzi will use nuclear magnetic resonance spectroscopy, microscopy and molecular simulation to probe the structures and interactions of several intrinsically disordered proteins. His project will serve as the foundation for understanding the structure, interactions, regulation and function of an entire class of RNA processing assemblies whose dysfunction has implications for several neurodegenerative diseases.