Advancing Quantitative Cancer Imaging in Clinical Trials (QIN)

The evolution in our understanding of cancer requires an evolution in the design and implementation of clinical trials, and the quantitative imaging used to assess therapeutic efficacy. This was noted in the Institute of Medicine's influential report A National Cancer Clinical Trials System for the 21st Century, which stated that 'the current structure and processes of the entire clinical trials system need to be redesigned to improve value by reducing redundancy and improving the effectiveness and efficiency of trials'. The goal of this study is to accelerate the development and deployment of quantitative imaging methods that improve the effectiveness and efficiency of clinical trials by using the combined resources of the American College of Radiology (ACR), the NCI-sponsored cooperative group ECOG-ACRIN (E-A), and the NCI Quantitative Imaging Network (QIN). To achieve this goal, and in accord with NOT-CA-13-011, this proposal is focused on supporting QIN network- wide research resources.

Jon Steingrimsson Ani Eloyan

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