Center faculty are leaders in developing and applying methods for meta-analysis, the quantitative combination of results from different studies. Prof. Gatsonis has pioneered the use of hierarchical summary ROC curves for assessing sensitivity and specificity and is developing methods for summarizing the predictive accuracy of diagnostic tests. Prof. Trikalinos heads the Center for Evidence Synthesis in Health which he co-founded with Prof. Schmid. They have developed a variety of different methods and software tools for synthesizing different types of data and studies including meta-analysis of diagnostic tests, multivariate outcomes and networks of treatments. Prof. Schmid also heads the Evidence Synthesis Academy, which aims to promote the wider use and understanding of meta-analysis among decision-makers.