Enzyme shown to regulate inflammation and metabolism in fat tissue

January 10, 2018

PROVIDENCE, R.I. [Brown University] —The human body has two primary kinds of fat—white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means of combating obesity.

Now, a study led by Brown University researchers has identified an enzyme that appears the regulate the physiology of both fat types in mice—decreasing inflammation in white fat tissue, while promoting the ability of brown fat to burn calories. Preliminary genetic evidence included in the study suggests that the enzyme, called SNRK, performs similar functions in humans, making it an intriguing new drug target in the battle against obesity and its complications. READ MORE