With $12.5M grant, Brown to create research center on substance misuse and chronic disease

PROVIDENCE, R.I.[Brown University] — With a new National Institutes of Health grant expected to total $12.5 million over five years, Brown University will expand its research on substance misuse and launch a new Center of Biomedical Research Excellence (COBRE).

Based at the University’s School of Public Health, the Center for Addiction and Disease Risk Exacerbation (CADRE) will focus on the intersection of substance use and disease. The center will establish at Brown a laboratory for collecting blood and other samples from patients to measure chemical markers, such as those of inflammation or stress. And the grant will support four early-career faculty members as they study substance use and chronic diseases — research questions on the interplay between alcohol and HIV on inflammation, for example, or whether cannabis can substitute for opioids in treating rheumatoid arthritis.

“Everyone knows about the relationship between tobacco use and lung cancer, but there are many other links between substance use and chronic diseases,” said Peter Monti, director of the Center for Alcohol and Addiction Studies (CAAS) at Brown and a professor of behavioral and social sciences who will lead the new COBRE. READ MORE