Alzheimer’s Research Group

We apply novel experimental and quasi-experimental methods to design and evaluate interventions and policies that aim to improve the quality of care for individuals with Alzheimer’s disease and related dementias and their caregivers.  Our research spans the continuum of care from the community to long-term care facilities.

Rosa R. Baier, MPH

Associate Director, Center for Long-Term Care Quality and & Innovation, Associate Professor of the Practice of Health Services, Policy and Practice

Baier leads a research center focused on improving care for older adults, including those living with Alzheimer’s and related dementias, by testing and disseminating proven interventions. Her pragmatic approach combines the practical considerations of quality improvement with the research methods necessary to ensure that findings are valid and can be replicated. She is PI or Co-I on several dementia intervention studies.

Research Profile

Judith D. Bentkover, PhD

Professor of the Practice of Health Services, Policy and Practice

Dr. Bentkover's research interests include the impact of healthcare policy on cost, access, and quality of the delivery and financing of medical services and the health of specific populations.  Her recent research relates to mental health including Alzheimer's Disease, Post Traumatic Stress, and Traumatic Brain Injury. 

Research Profile

Lori Daiello, PharmD, MS

Assistant Professor of Neurology (Research), Assistant Professor of Health Services, Policy and Practice (Research)

Dr. Daiello’s research explores how medications affect the trajectory of decline in cognitive and functional abilities and the development of neuropsychiatric symptoms in progressive degenerative dementias.

Research Profile

Ani Eloyan, PhD

Assistant Professor of Biostatistics

Dr. Eloyan’s research interests include semi-parametric likelihood-based methods for matrix decompositions, statistical analyses of brain images, and integration of various types of complex data structures for analyzing health care data.

Research Profile

Constantine A. Gatsonis, PhD

Henry Ledyard Goddard University Professor of Statistical Sciences, Director of Statistical Sciences, Professor of Biostatistics

Dr. Gatsonis’ research interests include statistical methods in diagnosis and prediction, Comparative Effectiveness Research methodology, Radiomics, Meta-analysis, and Bayesian biostatistics. He also engages in interdisciplinary research on clinical evaluation of diagnostic imaging for early detection, diagnosis, staging, and treatment of cancer, cancer care delivery research, and Comparative Effectiveness Research for cancer and cardiovascular disease.

Research Profile

Eric Jutkowitz, PhD

Assistant Professor of Health Services, Policy and Practice

Dr. Jutowitz’s research is focused on understanding the value and quality of care delivered to vulnerable populations with an emphasis on the role of the informal and formal long-term care system.

Research Profile

Gary P. Epstein-Lubow, MD

Associate Professor of Psychiatry and Human Behavior, Associate Professor of Medical Science, Associate Professor of Health Services, Policy and Practice

Dr. Epstein’s research, teaching and patient care seek to ease suffering of individuals with neuropsychiatric illness and their family caregivers. His specific research focus lies in  improving family-oriented dementia treatment. 

Research Profile

Ellen M. McCreedy

Assistant Professor of Health Services, Policy and Practice

Dr. McCreedy is interested in improving the quality of remaining life for people with dementia. Her research goals are to reduce the amount of futile and burdensome care received at the end of life; and to provide comfort, meaning, and moments of joy to people living with dementia and their families. 

Research Profile

Vince Mor, PhD

Florence Pirce Grant University Professor, Professor of Health Services, Policy and Practice

Dr. Mor’s research focuses on the organizational and health care delivery system factors associated with variation in use of health services, and outcomes experienced by frail and chronically ill persons. His areas of study include: the quality of nursing home care, Medicare funding for post-acute care, the determinants of hospitalization, disease management for cancer patients, and age and racial discrimination in health care treatments.

Research Profile

Whitney Mills, PhD

Assistant Professor of Health Services, Policy and Practice (Research)

Dr. Mills has a long-standing interest in improving the quality of life for older adults using long-term services and supports and expertise in qualitative and implementation science methods. Her work focuses on developing and testing interventions to improve nursing home quality, transitions of care, and assessment of decision-making capacity.

Research Profile

Edward A. Miller, PhD

Adjunct Professor of Health Services, Policy and Practice

Dr. Miller's research focuses on understanding the determinants and effects of federal and state policies affecting vulnerable populations, including the frail and disabled elderly, mentally ill, Veterans, and urban underserved. Whereas the conceptual focus of his studies is in state politics and policy, intergovernmental relations, program evaluation and implementation, the substantive focus is primarily in aging and long-term care, and telemedicine and e-health.

Research Profile

Susan C. Miller, PhD, MBA

Professor of Health Services, Policy and Practice

Dr. Miller studies nursing home end-of-life care and long-term care utilization and quality. Her ongoing research aims to understand the use of hospice care in nursing homes, how use is associated with state policies, and how hospice care influences quality. Another study is examining nursing home "culture change" practices, state policies associated with their adoption, and quality outcomes.

Research Profile

Maricruz Rivera-Hernandez, PhD

Assistant Professor of Health Services, Policy and Practice

Dr. Rivera-Hernandez’s research interests include racial and ethnic disparities in access to and quality of care, and health outcomes of older adults. Her specific research focus is on health disparities and healthcare issues of elderly Hispanics.

Research Profile

Momotazur Rahman, PhD

Assistant Professor of Health Services, Policy and Practice

Dr. Rahman is an economist interested in the organization and economic performance of the U.S. healthcare system. His research focuses on 1) disparities in health care access, utilization, and outcomes across different demographic and socio-economic groups, 2) the effects of managed care on the healthcare system and 3) the effects of regulation on healthcare markets. 

Research Profile

James L. Rudolph, MD

Professor of Medicine, Professor of Health Services, Policy and Practice

Dr. Rudolph is an active clinician and founding President of the American Delirium Society. His area of expertise is the relationship of functional (cognitive and physical) deficits as a predisposition to negative health events in older persons, particularly those who are hospitalized. Driven by his clinical work, his research assesses thinking and recovery after hospitalization using methodology that can be implemented into clinical practice.

Research Profile

Kali S. Thomas

Associate Professor of Health Services, Policy and Practice

Dr. Thomas conducts applied health services research to inform policies and practices that secure better health and quality of life outcomes for individuals who are aging and disabled, particularly those who require long-term services and supports (LTSS). Broadly, her research focuses on the organization and delivery of LTSS, with an emphasis on measurement and quality.

Research Profile

Early Onset Alzheimer’s Disease Consortium

Principal Investigator: Dr. Liana Apostolova
Biostatistics Core Lead: Dr. Ani Eloyan
Funding: National Institute of Health, National Institute on Aging
Years: 2017-2022

Comparative Effectiveness and Cost-Effectiveness, of Nondrug Interventions that Manage Function and Behavioral Symptoms in African American and White Persons with Alzheimer’s Disease

Principal Investigator: Dr. Eric Jutkowitz
Funding: National Institute on Aging, NIH
Years: 2018-2022

Informal Resources of Persons Living with Alzheimer’s Disease and Related Dementias: Impact on Hospitalizations, Potentially Avoidable Hospitalizations and Nursing Home Admissions

Principal Investigator: Dr. Eric Jutkowitz
Funding: National Institute on Aging, NIH
Years: 2019-2021

Disparity in Incidence and Health Outcomes between Rural and Urban Patients with Alzheimer’s disease and related disorders

Principal Investigator: Dr. Momotazur Rahman; Co-Investigator: Dr. Kali S. Thomas
Funding: National Institute on Aging, NIH
Years: 2017-2019

Nursing Home Care Disparities for Hispanic Medicare Advantage and Fee-for-Service Beneficiaries with Alzheimer’s and Related Dementias

Principal Investigator: Maricruz Rivera-Hernandez
Funding: National Institute on Aging, NIH
Years: 2018-2019

The NHCGNE Geriatric Nursing Leadership Training Program for Optimizing Quality in Long-Term Care

Principal Investigators: Dr. James Rudolph, Dr. Shaugnessy, Dr. Kolanowski
Co-Investigator: Dr. Whitney Mills
Funding: Research, Education, Caregiving, Alzheimer’s & Living (RECALL) Foundation
Years: 2018-2019

Me & My Wishes: An efficacy trial of long-term care residents with Alzheimer's using videos to communicate care preferences with caregivers

Principal Investigator: Rosa Baier
Funding: University of Utah College of Nursing
Years: 2018-2019

Implementing individualized dementia care and eliminating off-label antipsychotic medications in South Carolina nursing homes

Principal Investigator: Rosa Baier
Funding: Centers for Medicaid & Medicaid Services
Years: 2017-2019

LEDs for Sleep AND Mood Adjustment in Nursing homes (LED SANDMAN) Project 

Principal Investigator: Rosa Baier
Funding: McClung Foundation

Music & MEmory: A Pragmatic TRIal for Nursing Home Residents with ALzheimer's Disease (METRIcAL) TriaL

Principal Investigator: Dr. Vincent Mor
Funding: National Institutes on Aging, NIH
Years: 2017-2022

Alzheimer’s disease/Alzheimer’s disease and related dementias (AD/ADRD) Health Care Systems Research Collaboratory

Principal Investigator: Dr. Vincent Mor
Funding: National Institute on Aging, NIH
Years: 2019-2024

Baier, R. R., & Mor, V. (2017). Pragmatic trials may help to identify effective strategies to reduce nursing home antipsychotic medication use. Israel Journal of Health Policy Research, 6, 5. https://doi.org/10.1186/s13584-016-0130-3

Baier, R. R., Mitchell, S. L., Jutkowitz, E., & Mor, V. (2018). Identifying and Supporting Nonpharmacological Dementia Interventions Ready for Pragmatic Trials: Results From an Expert Workshop. Journal of the American Medical Directors Association, 19(7), 560–562. https://doi.org/10.1016/j.jamda.2018.02.011

Bentkover, J., Cai, S., Makineni, R., Mucha, L., Treglia, M., & Mor, V. (2012). Road to the nursing home: costs and disease progression among medicare beneficiaries with ADRD. American Journal of Alzheimer’s Disease and Other Dementias, 27(2), 90–99. https://doi.org/10.1177/1533317512440494

Brown, L. M., Dosa, D. M., Thomas, K., Hyer, K., Feng, Z., & Mor, V. (2012). The effects of evacuation on nursing home residents with dementia. American Journal of Alzheimer’s Disease and Other Dementias, 27(6), 406–412. https://doi.org/10.1177/1533317512454709

Daiello, L. A., Gongvatana, A., Dunsiger, S., Cohen, R. A., & Ott, B. R. (2015). Association of fish oil supplement use with preservation of brain volume and cognitive function. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association, 11(2), 226–235. https://doi.org/10.1016/j.jalz.2014.02.005

Fink, H. A., Jutkowitz, E., McCarten, J. R., Hemmy, L. S., Butler, M., Davila, H., … Kane, R. L. (2018). Pharmacologic Interventions to Prevent Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer-Type Dementia: A Systematic Review. Annals of Internal Medicine, 168(1), 39–51. https://doi.org/10.7326/M17-1529

Fong, T. G., Jones, R. N., Shi, P., Marcantonio, E. R., Yap, L., Rudolph, J. L., … Inouye, S. K. (2009). Delirium accelerates cognitive decline in Alzheimer disease. Neurology, 72(18), 1570–1575. https://doi.org/10.1212/WNL.0b013e3181a4129a

Fong, T. G., Fearing, M. A., Jones, R. N., Shi, P., Marcantonio, E. R., Rudolph, J. L., … Inouye, S. K. (2009). Telephone interview for cognitive status: Creating a crosswalk with the Mini-Mental State Examination. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 5(6), 492–497. https://doi.org/10.1016/j.jalz.2009.02.007

Godwin, K. M., Mills, W. L., Anderson, J. A., & Kunik, M. E. (2013). Technology-driven interventions for caregivers of persons with dementia: a systematic review. American Journal of Alzheimer’s Disease and Other Dementias, 28(3), 216–222. https://doi.org/10.1177/1533317513481091

Horvath, K. J., Trudeau, S. A., Rudolph, J. L., Trudeau, P. A., Duffy, M. E., & Berlowitz, D. (2013). Clinical trial of a home safety toolkit for Alzheimer’s disease. International Journal of Alzheimer’s Disease, 2013, 913606. https://doi.org/10.1155/2013/913606

Jalbert, J. J., Daiello, L. A., & Lapane, K. L. (2008). Dementia of the Alzheimer type. Epidemiologic Reviews, 30, 15–34. https://doi.org/10.1093/epirev/mxn008

Jutkowitz, E., Kuntz, K. M., Dowd, B., Gaugler, J. E., MacLehose, R. F., & Kane, R. L. (2017). Effects of cognition, function, and behavioral and psychological symptoms on out-of-pocket medical and nursing home expenditures and time spent caregiving for persons with dementia. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 13(7), 801–809. https://doi.org/10.1016/j.jalz.2016.12.011

Li, S., Eloyan, A., Joel, S., Mostofsky S.H., Pekar, J.J., Basset, S.S., and Caffo, B.S. (2012) Analysis of group ICA-based connectivity measures from fMRI: application to Alzheimer’s Disease. PLoS One. 7, 11. http://doi.org/10.1371/journal.pone.0049340.

McCreedy, E., Baier, R., Thomas, K., & Mor, V. (2018). Effects of music and memory on agitated and aggressive behaviors in dementia: Results from nursing home pilot study. Innovation in Aging, 2 (Suppl 1), 953–954. https://doi.org/10.1093/geroni/igy031.3536

McCreedy, E. M., Yang, X., Baier, R. R., Rudolph, J. L., Thomas, K. S., & Mor, V. (2019). Measuring Effects of Nondrug Interventions on Behaviors: Music & Memory Pilot Study. Journal of the American Geriatrics Society, 0(0). https://doi.org/10.1111/jgs.16069

Miller, E. A., Rosenheck, R. A., & Schneider, L. S. (2012). Caregiver burden, health utilities, and institutional service use in Alzheimer’s Disease. International Journal of Geriatric Psychiatry, 27(4), 382–393. https://doi.org/10.1002/gps.2730

Miller, E. A., Schneider, L. S., & Rosenheck, R. A. (2011). Predictors of Nursing Home Admission among Alzheimer’s Disease Patients with Psychosis and/or Agitation. International Psychogeriatrics / IPA, 23(1), 44–53. https://doi.org/10.1017/S1041610210000244

Miller, E. A., Rosenheck, R. A., & Schneider, L. S. (2010). Caregiver burden, health utilities and institutional service costs among community-dwelling patients with Alzheimer’s disease. Alzheimer Disease and Associated Disorders, 24(4), 380–389. https://doi.org/10.1097/WAD.0b013e3181eb2f2e

Miller, S. C., Lima, J. C., & Mitchell, S. L. (2010). Hospice care for persons with dementia: The growth of access in US nursing homes. American Journal of Alzheimer’s Disease and Other Dementias, 25(8), 666–673. https://doi.org/10.1177/1533317510385809

Miller, S. C., Lima, J. C., & Mitchell, S. L. (2010). Hospice care in U.S. nursing homes for persons with end-stage dementia: How U.S. medicare payment policy influences hospice election and end-of-life hospitalizations. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, 6(4), S337. https://doi.org/10.1016/j.jalz.2010.05.1129

Miller, E. A., Rosenheck, R. A., & Schneider, L. S. (2010). Assessing the relationship between health utilities, quality of life, and health care costs in Alzheimer’s disease: The CATIE-AD study. Current Alzheimer Research, 7(4), 348–357.

Miller, E. A., Schneider, L. S., Zbrozek, A., & Rosenheck, R. A. (2008). Sociodemographic and clinical correlates of utility scores in Alzheimer’s disease. Value in Health: The Journal of the International Society for Pharmacoeconomics and Outcomes Research, 11(7), 1120–1130. https://doi.org/10.1111/j.1524-4733.2008.00351.x

Rosenheck, R. A., Leslie, D. L., Sindelar, J. L., Miller, E. A., Tariot, P. N., Dagerman, K. S., … Clinical Antipsychotic Trial of Intervention Effectiveness-Alzheimer’s Disease (CATIE-AD) investigators. (2007). Cost-benefit analysis of second-generation antipsychotics and placebo in a randomized trial of the treatment of psychosis and aggression in Alzheimer disease. Archives of General Psychiatry, 64(11), 1259–1268. https://doi.org/10.1001/archpsyc.64.11.1259

Ott, B. R., Jones, R. N., Daiello, L. A., de la Monte, S. M., Stopa, E. G., Johanson, C. E., … Grammas, P. (2018). Blood-Cerebrospinal Fluid Barrier Gradients in Mild Cognitive Impairment and Alzheimer’s Disease: Relationship to Inflammatory Cytokines and Chemokines. Frontiers in Aging Neuroscience, 10, 245. https://doi.org/10.3389/fnagi.2018.00245

Rivera-Hernandez, M., Kumar, A., Epstein-Lubow, G., & Thomas, K. S. (2018). Disparities in Nursing Home Use and Quality Among African American, Hispanic, and White Medicare Residents With Alzheimer’s Disease and Related Dementias. Journal of Aging and Health, 898264318767778. https://doi.org/10.1177/0898264318767778

Rudolph, J. L., Zanin, N. M., Jones, R. N., Marcantonio, E. R., Fong, T. G., Yang, F. M., … Inouye, S. K. (2010). Hospitalization in community-dwelling persons with Alzheimer’s disease: frequency and causes. Journal of the American Geriatrics Society, 58(8), 1542–1548. https://doi.org/10.1111/j.1532-5415.2010.02924.x

Thomas, K. & Baier, R., Kosar, C., Ogarek, J., Trepman, A., & Mor, V. (2017). Individualized Music Program is Associated with Improved Outcomes for U.S. Nursing Home Residents with Dementia. The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry, 25(9), 931–938. https://doi.org/10.1016/j.jagp.2017.04.008