Faculty and fellows of the Center for Evidence Synthesis in Health regularly present at professional conferences and publish in top tier medical and methodological journals.

For updates regarding the Center's most current publications search the US National Library of Medicine,  A sample of recent publications follows by category.

Methods Guidance on Evidence Synthesis, Modelling or Decision Analysis 

Sanders GD, Neumann PJ, Basu A, Brock DW, Feeny D, Krahn M, Kuntz KM, Meltzer DO, Owens DK, Prosser LA, Salomon JA, Sculpher MJ, Trikalinos TA, Russell LB, Siegel JE, Ganiats TG. Recommendations for Conduct, Methodological Practices, and Reporting of Cost-Effectiveness Analyses in Health and Medicine: the Second Panel on Cost-Effectiveness in Health and Medicine. JAMA.  2016;316(10):1093-1103. doi:10.1001/jama.2016.12195.

Empirical Research in Evidence Synthesis 

Trikalinos TA, Hoaglin DC, Schmid CH. An empirical comparison of univariate and multivariate meta-analyses for categorical outcomes. Stat Med. 2014 Apr 30;33(9):1441-59. doi: 10.1002/sim.6044. Epub 2013 Nov 28. PubMed PMID: 24285290.

Yu WW, Schmid CH, Lichtenstein AH, Lau J, Trikalinos TA. Empirical evaluation of meta-analytic approaches for nutrient and health outcome dose-response data. Res Synth Methods. 2013 Sep;4(3):256-268. PubMed PMID: 25379059; PubMed Central PMCID: PMC4219760.

Trikalinos TA, Hoaglin DC, Schmid CH. Empirical and Simulation-Based Comparison of Univariate and Multivariate Meta-Analysis for Binary Outcomes. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Mar. Available from PubMed PMID: 23617018.

Dahabreh IJ, Trikalinos TA, Lau J, Schmid C. An Empirical Assessment of Bivariate Methods for Meta-Analysis of Test Accuracy. Rockville (MD): Agency for Healthcare Research and Quality (US); 2012 Nov. Available from PubMed PMID: 23326899.

Dahabreh IJ, Chung M, Kitsios GD, Terasawa T, Raman G, Tatsioni A, Tobar A, Lau J, Trikalinos TA, Schmid CH. Comprehensive Overview of Methods and Reporting of Meta-Analyses of Test Accuracy. Rockville (MD): Agency for Healthcare Research and Quality (US); 2012 Mar. Available from PubMed PMID: 22553887.

Kitsios GD, Dahabreh IJ, Trikalinos TA, Schmid CH, Huggins GS, Kent DM. Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies. Circ Cardiovasc Genet. 2011 Feb;4(1):58-67. doi: 10.1161/CIRCGENETICS.110.957738. Epub 2010 Dec 13. PubMed PMID: 21149552; PubMed Central PMCID: PMC3048058.

Applied Evidence Synthesis

Di M, Liu H, Yang Z, Bonis PA, Tang J, Lau J. Prediction Models of Mortality in Acute Pancreatitis in Adults: A Systematic Review. J Gen Ann Intern Med. [Epub ahead of print 26 July 2016] doi:10.7326/M16-0650

Ott BR, Daiello LA, Dahabreh IJ, Springate BA, Bixby K, Murali M, Trikalinos TA. Do Statins Impair Cognition? A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Gen Intern Med. 2015 Jan 10. [Epub ahead of print] PubMed PMID: 25575908

 Bannuru RR, Schmid CH, Kent DM, Vaysbrot EE, Wong JB, McAlindon TE. Comparative Effectiveness of Pharmacologic Interventions for Knee Osteoarthritis: A Systematic Review and Network Meta-analysis. Ann Intern Med. 2015 Jan 6;162(1):46-54. doi: 10.7326/M14-1231. PubMed PMID: 25560713.

Kelly MJ, Trikalinos TA, Dahabreh IJ, Gianferante M, Parsons SK. Cranial radiation for pediatric T-lineage acute lymphoblastic leukemia: a systematic review and meta-analysis. Am J Hematol. 2014 Oct;89(10):992-7. doi: 10.1002/ajh.23784. Epub 2014 Jul 22. Review. PubMed PMID: 24912665; PubMed Central PMCID: PMC4167220.

Decision and Simulation Modeling & Decision Making
Trikalinos TA, Siebert U, Lau JDecision-analytic modeling to evaluate benefits and harms of medical tests: uses and limitations. Med Decis Making2009 Sep-Oct;29(5):E22-9. doi: 10.1177/0272989X09345022. PMID:19734441

Trikalinos TA, Kulasingam S, Lawrence WF. Chapter 10: deciding whether to complement a systematic review of medical tests with decision modeling.  J Gen Intern Med. 2012 Jun;27 Suppl 1:S76-82. doi: 10.1007/s11606-012-2019-3. PMID: 22648678

Quantitative methods

Trikalinos TA, Olkin I. Meta-analysis of effect sizes reported at multiple time points: a multivariate approach. Clin Trials. 2012 Oct;9(5):610-20. doi: 10.1177/1740774512453218. Epub 2012 Aug 7. PubMed PMID: 22872546.

Trikalinos TA, Olkin I. A method for the meta-analysis of mutually exclusive binary outcomes. Stat Med. 2008 Sep 20;27(21):4279-300. doi: 10.1002/sim.3299. PubMed PMID: 18416445.

Trikalinos TA, Trow P, Schmid CH. Simulation-Based Comparison of Methods for Meta-Analysis of Proportions and Rates. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Nov. Available from PubMed PMID: 24404633.

 Trikalinos TA, Hoaglin DC, Small KM, Schmid CH. Evaluating Practices and Developing Tools for Comparative Effectiveness Reviews of Diagnostic Test Accuracy: Methods for the Joint Meta-Analysis of Multiple Tests. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Jan. Available from PubMed PMID: 23865097.

Non-Quantitative Methods 

Concannon TW, Fuster M, Saunders T, Patel K, Wong JB, Leslie LK, Lau J. A systematic review of stakeholder engagement in comparative effectiveness and patient-centered outcomes research. J Gen Intern Med. 2014 Dec;29(12):1692-701. doi: 10.1007/s11606-014-2878-x. Epub 2014 Jun 4. PubMed PMID: 24893581; PubMed Central PMCID: PMC4242886. 

 Li T, Vedula SS, Hadar N, Parkin C, Lau J, Dickersin K. Innovations in Data Collection, Management, and Archiving for Systematic Reviews. Ann Intern Med. 2015 Feb 17;162(4):287-294. doi: 10.7326/M14-1603. PubMed PMID: 25686168.

Schully SD, Lam TK, Dotson WD, Chang CQ, Aronson N, Birkeland ML, Brewster SJ, Boccia S, Buchanan AH, Calonge N, Calzone K, Djulbegovic B, Goddard KA, Klein RD, Klein TE, Lau J, Long R, Lyman GH, Morgan RL, Palmer CG, Relling MV, Rubinstein WS, Swen JJ, Terry SF, Williams MS, Khoury MJ. Evidence synthesis and guideline development in genomic medicine: current status and future prospects. Genet Med. 2015 Jan;17(1):63-7. doi: 10.1038/gim.2014.69. Epub 2014 Jun 19. PubMed PMID: 24946156; PubMed Central PMCID: PMC4272332.

Text Mining in Healthcare

Wallace BC, Paul MJ, Sarkar U, Trikalinos TA, Dredze M. A large-scale quantitative analysis of latent factors and sentiment in online doctor reviews. J Am Med Inform Assoc. 2014 Nov-Dec;21(6):1098-103. doi: 10.1136/amiajnl-2014-002711. Epub 2014 Jun 10. PubMed PMID: 24918109; PubMed Central PMCID: PMC4215053. 

Wallace BC, Laws MB, Small K, Wilson IB, Trikalinos TA.  Automatically annotating topics in transcripts of patient-provider interactions via machine learning.  Med Decis Making. 2014 May;34(4):503-12. doi: 10.1177/0272989X13514777. Epub 2013 Nov 27. PMID: 24285151

Optimizing the Processes of Evidence Synthesis

Wallace BC, Dahabreh IJ, Schmid CH, Lau J, Trikalinos TA. Modernizing the systematic review process to inform comparative effectiveness: tools and methods. J Comp Eff Res. 2013 May;2(3):273-82. doi: 10.2217/cer.13.17. PubMed PMID: 24236626.
Wallace BC, Small K, Brodley CE, Lau J, Schmid CH, Bertram L, Lill CM, Cohen JT, Trikalinos TA. Toward modernizing the systematic review pipeline in genetics: efficient updating via data mining. Genet Med. 2012 Jul;14(7):663-9. PubMed PMID: 22481134; PubMed Central PMCID: PMC3908550. 
Castaldi PJ, Cho MH, Cohn M, Langerman F, Moran S, Tarragona N, Moukhachen H, Venugopal R, Hasimja D, Kao E, Wallace B, Hersh CP, Bagade S, Bertram L, Silverman EK, Trikalinos TA. The COPD genetic association compendium: a comprehensive online database of COPD genetic associations. Hum Mol Genet. 2010 Feb 1;19(3):526-34. doi: 10.1093/hmg/ddp519. Epub 2009 Nov 20. PubMed PMID: 19933216; PubMed Central PMCID: PMC2798725.

Tools and Software

Wallace BC, Trikalinos TA, Lau J, Brodley C, Schmid CH. Semi-automated screening of biomedical citations for systematic reviews. BMC Bioinformatics. 2010 Jan 26;11:55. doi: 10.1186/1471-2105-11-55. PubMed PMID: 20102628; PubMed Central PMCID: PMC2824679.
Wallace BC, Schmid CH, Lau J, Trikalinos TA. Meta-Analyst: software for meta-analysis of binary, continuous and diagnostic data. BMC Med Res Methodol. 2009 Dec 4;9:80. doi: 10.1186/1471-2288-9-80. PubMed PMID: 19961608; PubMed Central PMCID: PMC2795760.

Predictive and Risk Modeling

Inker LA, Lambers Heerspink HJ, Mondal H, Schmid CH, Tighiouart H, Noubary F, Coresh J, Greene T, Levey AS. GFR decline as an alternative end point to kidney failure in clinical trials: a meta-analysis of treatment effects from 37 randomized trials. Am J Kidney Dis. 2014 Dec;64(6):848-59. doi: 10.1053/j.ajkd.2014.08.017. Epub 2014 Oct 16. PubMed PMID: 25441438.

Varvarigou V, Farioli A, Korre M, Sato S, Dahabreh IJ, Kales SN. Law enforcement duties and sudden cardiac death among police officers in United States: case distribution study. BMJ. 2014 Nov 18;349:g6534. doi: 10.1136/bmj.g6534. PubMed PMID: 25406189; PubMed Central PMCID: PMC4240529.

Theoretical foundations of Evidence Synthesis

Trikalinos  TA, Dahabreh IJ, Wallace BC, Schmid CH, Lau J.  Towards a Framework For Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses [Internet].  Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Sep. PMID: 24156117