Epidemiology of HIV Antiretroviral Exposure from Whoonga Use in South Africa

Multiple Principal Investigators
Matthew Mimiaga, ScD, MPH
David John Grelotti, MD (University of California, San Diego)

Sponsor: National Institutes of Health (NIH)/National Institute on Drug Abuse (NIDA)

Grant Number:
1R21DA039857-01

Some people are exposed to HIV antiretroviral medication through recreational use. This emerging phenomenon poses a significant obstacle to efforts to address the global HIV pandemic. Any antiretroviral exposure from recreational use may increase rates of antiretroviral-resistant HIV strains. This and any diversion of antiretroviral medication for recreational use will increase the cost of delivering this life-saving care. The proposed research will document antiretroviral exposure from the use of whoonga, a drug cocktail in South Africa that may contain antiretroviral medication and illicit drugs. It will also inform future research to link recreational antiretroviral use to antiretroviral resistance among HIV-infected individuals who have yet to initiate HIV treatment, as well as promote the design of culturally appropriate interventions.