Eleftherios Mylonakis

Charles C.J. Carpenter, MD Professor of Infectious Diseases, Professor of Medicine, Assistant Dean of Medicine, Professor of Molecular Microbiology and Immunology


The Mylonakis lab developed new models to identify novel antimicrobials and study basic, evolutionarily conserved aspects of microbial virulence and host response. Also, established the cost-effectiveness of antimicrobial stewardship and new diagnositics. His work identified new classes of antimicrobial compounds, new targets for antimicrobial therapy and a deeper understanding of host–pathogen interaction.   This diverse background includes areas such as molecular biology, immunology, biostatistics, decision-making analysis, risk assessment, outcomes research and cost-effectiveness studies. These investigations have identified novel virulence factors, cross kingdom pathogen-pathogen interactions, novel antimicrobial agents and evolutionarily conserved traits that are involved in host virulence and immune responses during infection.